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2020-09-01Zeitschriftenartikel
Hepatitis E virus genome detection in commercial pork livers and pork meat products in Germany
dc.contributor.authorPallerla, Srinivas Reddy
dc.contributor.authorSchembecker, Sonja
dc.contributor.authorMeyer, Christian G.
dc.contributor.authorLinh, Le Thi Kieu
dc.contributor.authorJohne, Reimar
dc.contributor.authorWedemeyer, Heiner
dc.contributor.authorBock, Claus-Thomas
dc.contributor.authorKremsner, Peter G.
dc.contributor.authorVelavan, Thirumalaisamy P.
dc.date.accessioned2024-08-22T15:59:40Z
dc.date.available2024-08-22T15:59:40Z
dc.date.issued2020-09-01none
dc.identifier.other10.1111/jvh.13396
dc.identifier.urihttp://edoc.rki.de/176904/11949
dc.description.abstractThe hepatitis E virus (HEV) is one of the most common causes of hepatitis worldwide. HEV is also widespread in many developed countries, where the number of infections is steadily increasing. In those countries, the virus is transmitted mainly through consumption of undercooked or raw food or through contact with animals. Especially, pigs serve as a main reservoir of HEV. Here, we investigated the prevalence of HEV RNA in pork livers and pork meat products to assess the actual risk of HEV infection through food consumption in Germany. A total of 131 pork products were collected from grocery stores and butcher shops between October 2019 and February 2020 and screened for HEV RNA using nested PCR and subsequent sequencing. Overall, 10% of the samples were positive for HEV, including pork livers (5%), spreadable liver sausages (13%) and liver pâté samples (15%). Sequence analyses indicated that the large majority of HEV strains belonged to subtype HEV-3c, representing the most frequent subtype in Germany. One sample belonged to subtype HEV-3f. Further sequence analysis revealed large sequence variation between the samples; however, most of the mutations identified were synonymous. Although infectivity of the virus was not tested, the results suggest a considerable risk of HEV infection through food consumption. Therefore, preventive measures should be taken according to a One Health approach.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectEuropeeng
dc.subjectGermanyeng
dc.subjecthepatitis Eeng
dc.subjectmeateng
dc.subjectpork productseng
dc.subjectzoonosiseng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleHepatitis E virus genome detection in commercial pork livers and pork meat products in Germanynone
dc.typearticle
dc.identifier.urnurn:nbn:de:0257-176904/11949-9
dc.type.versionpublishedVersionnone
local.edoc.container-titleJournal of Viral Hepatitisnone
local.edoc.container-issn1365-2893none
local.edoc.pages9none
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://onlinelibrary.wiley.com/journal/13652893none
local.edoc.container-publisher-nameJohn Wiley & Sons, Incnone
local.edoc.container-volume28none
local.edoc.container-issue01none
local.edoc.container-reportyear2020none
local.edoc.container-firstpage196none
local.edoc.container-lastpage204none
dc.description.versionPeer Reviewednone

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