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2012-04-18Zeitschriftenartikel DOI: 10.1371/journal.pone.0035197
Sharing more than friendship--nasal colonization with coagulase-positive staphylococci (CPS) and co-habitation aspects of dogs and their owners.
dc.contributor.authorWalther, Birgit
dc.contributor.authorHermes, Julia
dc.contributor.authorCuny, Christiane
dc.contributor.authorWieler, Lothar H.
dc.contributor.authorVincze, Szilvia
dc.contributor.authorElnaga, Yassmin Abou
dc.contributor.authorStamm, Ivonne
dc.contributor.authorKopp, Peter A.
dc.contributor.authorKohn, Barbara
dc.contributor.authorWitte, Wolfgang
dc.contributor.authorJansen, Andreas
dc.contributor.authorConraths, Franz J.
dc.contributor.authorSemmler, Torsten
dc.contributor.authorEckmanns, Tim
dc.contributor.authorLübke-Becker, Antina
dc.date.accessioned2018-05-07T15:41:49Z
dc.date.available2018-05-07T15:41:49Z
dc.date.created2012-06-06
dc.date.issued2012-04-18none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/re6eyZlHRWPn2/PDF/24uTbtCsW56U.pdf
dc.identifier.urihttp://edoc.rki.de/176904/1232
dc.description.abstractBackground: Since the relationship between dogs and their owners has changed, and dogs moved from being working dogs to family members in post-industrial countries, we hypothesized that zoonotic transmission of opportunistic pathogens like coagulase positive staphylococci (CPS) is likely between dogs and their owners. Methodology/Principal Findings: CPS- nasal carriage, different aspects of human-to-dog relationship as well as potential interspecies transmission risk factors were investigated by offering nasal swabs and a questionnaire to dog owners (108) and their dogs (108) at a dog show in 2009. S. aureus was found in swabs of 20 (18.5%) humans and two dogs (1.8%), and spa types which correspond to well known human S. aureus lineages dominated (e.g. CC45, CC30 and CC22). Multilocus sequence typing (MLST) of the two canine strains revealed ST72 and ST2065 (single locus variant of ST34). Fifteen dogs (13.9%) and six owners (5.6%) harboured S. pseudintermedius, including one mecA-positive human isolate (MRSP). Pulsed field gel electrophoresis (PFGE) revealed that one dog/owner pair harboured indistinguishable S. pseudintermedius- isolates of ST33. Ten (48%) of the 21 S. pseudintermedius-isolates showed resistance towards more than one antimicrobial class. 88.9% of the dog owners reported to allow at least one dog into the house, 68.5% allow the dog(s) to rest on the sofa, 39.8% allow their dogs to come onto the bed, 93.5% let them lick their hands and 52.8% let them lick their face. Bivariate analysis of putative risk factors revealed that dog owners who keep more than two dogs have a significantly higher chance of being colonized with S. pseudintermedius than those who keep 1–2 dogs (p,0.05). Conclusions/Recommendations: In conclusion, CPS transmission between dog owners and their dogs is possible. Further investigation regarding interspecies transmission and the diverse adaptive pathways influencing the epidemiology of CPS (including MRSA and MRSP) in different hosts is needed.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Infektionskrankheiten / Erreger
dc.subjectAdulteng
dc.subjectHumanseng
dc.subjectFemaleeng
dc.subjectMaleeng
dc.subjectMiddle Agedeng
dc.subjectRisk Factorseng
dc.subjectAnimalseng
dc.subjectAgedeng
dc.subjectYoung Adulteng
dc.subjectStaphylococcal Infections/microbiologyeng
dc.subjectAged 80 and overeng
dc.subjectBacterial Typing Techniques/methodseng
dc.subjectDogseng
dc.subjectNose/microbiologyeng
dc.subjectCoagulase/analysiseng
dc.subjectStaphylococcal Infections/transmissioneng
dc.subjectStaphylococcus/classificationeng
dc.subjectStaphylococcus/geneticseng
dc.subject.ddc610 Medizin
dc.titleSharing more than friendship--nasal colonization with coagulase-positive staphylococci (CPS) and co-habitation aspects of dogs and their owners.
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10024537
dc.identifier.doi10.1371/journal.pone.0035197
dc.identifier.doihttp://dx.doi.org/10.25646/1157
local.edoc.container-titlePLoS ONE
local.edoc.container-textWalther B, Hermes J, Cuny C, Wieler LH, Vincze S, et al. (2012)Sharing More than Friendship — Nasal Colonization with Coagulase-Positive Staphylococci (CPS) and Co-Habitation Aspects of Dogs and Their Owners.PLoS ONE 7(4): e35197.
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0035197
local.edoc.container-publisher-namePublic Library of Science
local.edoc.container-volume7
local.edoc.container-issue4
local.edoc.container-year2012

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