2023-05-04Zeitschriftenartikel
Direct and indirect vaccination effects on SARS-CoV-2 infection in day-care centres: Evaluating the policy for early vaccination of day-care staff in Germany, 2021
dc.contributor.author | Schoeps, Anja | |
dc.contributor.author | Walter, Jan | |
dc.contributor.author | Vogt, Manfred | |
dc.contributor.author | Bent, Stefan | |
dc.contributor.author | Philipp, Zanger | |
dc.contributor.author | the Palatina Public Health Study Group | |
dc.date.accessioned | 2025-08-01T08:32:23Z | |
dc.date.available | 2025-08-01T08:32:23Z | |
dc.date.issued | 2023-05-04 | none |
dc.identifier.other | 10.1017/S0950268823000638 | |
dc.identifier.uri | http://edoc.rki.de/176904/12872 | |
dc.description.abstract | To mitigate the known high transmission risk in day-care facilities for children aged 0–6 years, day-care staff were given priority for SARS-CoV-2 vaccination in Rhineland-Palatinate, Germany, in March 2021. This study assessed direct and indirect effects of early vaccination of day-care staff on SARS-CoV-2 transmission in daycares with the aim to provide a basis for the prioritisation of scarce vaccines in the future. Data came from statutory infectious disease notifications in educational institutions and from in-depth investigations by the district public health authorities. Using interrupted time series analyses, we measured the effect of mRNA-based vaccination of day-care staff on SARS-CoV-2 infections and transmission. Among 566 index cases from day-care centres, the mean number of secondary SARS-CoV-2 infections per index case dropped by −0.60 case per month after March 2021. The proportion of staff among all cases reported from daycares was around 60% in the pre-interruption phase and significantly decreased by 27 percentage points immediately in March 2021 and by further 6 percentage points each month in the post-interruption phase. Early vaccination of day-care staff reduced SARS-CoV-2 cases in the overall day-care setting and thus also protected unvaccinated children. This should inform future decisions on vaccination prioritisation. | eng |
dc.language.iso | eng | none |
dc.publisher | Robert Koch-Institut | |
dc.rights | (CC BY 3.0 DE) Namensnennung 3.0 Deutschland | ger |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/de/ | |
dc.subject | SARS-CoV-2 | eng |
dc.subject | Vaccination | eng |
dc.subject | Child Daycare Centers | eng |
dc.subject | Staff | eng |
dc.subject | Interrupted Time Series Analysis | eng |
dc.subject | Transmission | eng |
dc.subject.ddc | 610 Medizin und Gesundheit | none |
dc.title | Direct and indirect vaccination effects on SARS-CoV-2 infection in day-care centres: Evaluating the policy for early vaccination of day-care staff in Germany, 2021 | none |
dc.type | article | |
dc.identifier.urn | urn:nbn:de:0257-176904/12872-1 | |
dc.type.version | publishedVersion | none |
local.edoc.container-title | Epidemiology & Infection | none |
local.edoc.type-name | Zeitschriftenartikel | |
local.edoc.container-type | periodical | |
local.edoc.container-type-name | Zeitschrift | |
local.edoc.container-publisher-name | Cambridge University Press | none |
local.edoc.container-reportyear | 2023 | none |
local.edoc.container-firstpage | 1 | none |
local.edoc.container-lastpage | 4 | none |
dc.description.version | Peer Reviewed | none |