Emergence of OXA-48-type carbapenemase-producing Enterobacteriaceae in German hospitals
dc.contributor.author | Pfeifer, Yvonne | |
dc.contributor.author | Schlatterer, Kathrin | |
dc.contributor.author | Engelmann, Elisabeth | |
dc.contributor.author | Schiller, Reinhold A. | |
dc.contributor.author | Frangenberg, Hans Reiner | |
dc.contributor.author | Stiewe, Doris | |
dc.contributor.author | Holfelder, Martin | |
dc.contributor.author | Witte, Wolfgang | |
dc.contributor.author | Nordmann, Patrice | |
dc.contributor.author | Poirel, Laurent | |
dc.date.accessioned | 2018-05-07T15:54:28Z | |
dc.date.available | 2018-05-07T15:54:28Z | |
dc.date.created | 2012-09-14 | |
dc.date.issued | 2012-01-30 | none |
dc.identifier.other | http://edoc.rki.de/oa/articles/reJYU7KETGFdY/PDF/27pM8OzzmjPQ.pdf | |
dc.identifier.uri | http://edoc.rki.de/176904/1301 | |
dc.description.abstract | Nine carbapenem-resistant Enterobacteriaceae isolates collected from eight patients in five German hospitals were investigated. Six isolates produced the OXA-48 carbapenemase, and three isolates produced OXA-162, which is a point mutant form of OXA-48. Both carbapenemase genes were located on IncL/M-type conjugative plasmids. Insertion sequence IS1999 (truncated or not by IS1R) was located upstream of the bla(OXA-48) and bla(OXA-162) genes in all of the isolates. Pulsed-field gel electrophoresis typing indicated the clonal transmission of an OXA-48-producing Klebsiella pneumoniae strain in two hospitals. | eng |
dc.language.iso | eng | |
dc.publisher | Robert Koch-Institut, Infektionskrankheiten / Erreger | |
dc.subject | Anti-Bacterial Agents/pharmacology | eng |
dc.subject | Humans | eng |
dc.subject | Escherichia coli/genetics | eng |
dc.subject | Germany | eng |
dc.subject | Polymerase Chain Reaction | eng |
dc.subject | Hospitals | eng |
dc.subject | Cross Infection/microbiology | eng |
dc.subject | Bacterial Proteins/genetics | eng |
dc.subject | Microbial Sensitivity Tests | eng |
dc.subject | Pulsed-Field | eng |
dc.subject | Cross Infection/transmission | eng |
dc.subject | beta-Lactamases/biosynthesis | eng |
dc.subject | Bacterial Proteins/biosynthesis | eng |
dc.subject | beta-Lactamases/genetics | eng |
dc.subject | Plasmids/genetics | eng |
dc.subject | Enterobacteriaceae/drug effects | eng |
dc.subject | DNA Transposable Elements | eng |
dc.subject | Conjugation Genetic | eng |
dc.subject | Electrophoresis Gel | eng |
dc.subject | Drug Resistance Multiple Bacterial/genetics | eng |
dc.subject | Enterobacteriaceae/enzymology | eng |
dc.subject | Enterobacteriaceae Infections/microbiology | eng |
dc.subject | Enterobacteriaceae Infections/transmission | eng |
dc.subject | Escherichia coli/drug effects | eng |
dc.subject.ddc | 610 Medizin | |
dc.title | Emergence of OXA-48-type carbapenemase-producing Enterobacteriaceae in German hospitals | |
dc.type | periodicalPart | |
dc.identifier.urn | urn:nbn:de:0257-10027141 | |
dc.identifier.doi | 10.1128/AAC.05315-11 | |
dc.identifier.doi | http://dx.doi.org/10.25646/1226 | |
local.edoc.container-title | Antimicrobial Agents and Chemotherapy | |
local.edoc.container-text | Pfeifer, Y., Schlatterer, K., Engelmann, E., Schiller, R.A., Frangenberg, H.R., Stiewe, D., Holfelder, M., Witte, W., Nordmann, P., Poirel, L. Emergence of OXA-48-type carbapenemase-producing Enterobacteriaceae in German hospitals (2012) Antimicrobial Agents and Chemotherapy, 56 (4), pp. 2125-2128. | |
local.edoc.fp-subtype | Artikel | |
local.edoc.type-name | Zeitschriftenartikel | |
local.edoc.container-type | periodical | |
local.edoc.container-type-name | Zeitschrift | |
local.edoc.container-url | http://aac.asm.org/content/early/2012/01/25/AAC.05315-11 | |
local.edoc.container-publisher-name | American Society for Microbiology | |
local.edoc.container-volume | 56 | |
local.edoc.container-issue | 4 | |
local.edoc.container-year | 2012 |