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2013-03-21Zeitschriftenartikel DOI: 10.25646/1376
Challenges in diagnosing extrapulmonary tuberculosis in the European Union, 2011
dc.contributor.authorSolovic, I.
dc.contributor.authorJonsson, J.
dc.contributor.authorKorzeniewska-Kosela, M.
dc.contributor.authorChiotan, D. I.
dc.contributor.authorPace-Asciak, A.
dc.contributor.authorSlump, E.
dc.contributor.authorRumetshofer, R.
dc.contributor.authorAbubakar, I.
dc.contributor.authorKos, S.
dc.contributor.authorSvetina-Sorli, P.
dc.contributor.authorHaas, Walter
dc.contributor.authorBauer, T.
dc.contributor.authorSandgren, A.
dc.contributor.authorWerf, Marieke van der
dc.date.accessioned2018-05-07T16:22:18Z
dc.date.available2018-05-07T16:22:18Z
dc.date.created2013-04-09
dc.date.issued2013-03-21none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/re3zvxTN2DEWw/PDF/21dXPIoMzhDeM.pdf
dc.identifier.urihttp://edoc.rki.de/176904/1451
dc.description.abstractIn the European Union (EU) 72,334 tuberculosis (TB) cases were notified in 2011, of which 16,116 (22%) had extrapulmonary tuberculosis (EPTB). The percentage of TB cases with EPTB ranged from 4% to 48% in the reporting countries. This difference might be explained by differences in risk factors for EPTB or challenges in diagnosis. To assess the practices in diagnosis of EPTB we asked European Union/European Economic Area (EU/EEA) countries to participate in a report describing the diagnostic procedures and challenges in diagnosing EPTB. Eleven EU Member States participated and reports showed that in the majority EPTB is diagnosed by a pulmonologist, sometimes in collaboration with the doctor who is specialised in the organ where the symptoms presented. In most countries a medical history and examination is followed by invasive procedures, puncture or biopsy, to collect material for confirmation of the disease (by culture/histology/cytology). Some countries also use the tuberculin skin test or an interferon-gamma-release-assay. A wide variety of radiological tests may be used. Countries that reported challenges in the diagnosis of EPTB reported that EPTB is often not considered because it is a rare disease and most medical professionals will not have experience in diagnosing EPTB. The fact that EPTB can present with a variety of symptoms that may mimic symptoms of other pathologies does pose a further challenge in diagnosis. In addition, obtaining an appropriate sample for confirmation of EPTB was frequently mentioned as a challenge. In summary, diagnosis of EPTB poses challenges due to the diversity of symptoms with which EPTB may present, the low level of suspicion of clinicians, and due to the difficulty in obtaining an adequate sample for confirmation.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Infektionsepidemiologie
dc.subjectHumanseng
dc.subjectAnnual Reports as Topiceng
dc.subjectBacterial Infectionseng
dc.subjectEuropeeng
dc.subjectPublicationseng
dc.subject.ddc610 Medizin
dc.titleChallenges in diagnosing extrapulmonary tuberculosis in the European Union, 2011
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10030006
dc.identifier.doihttp://dx.doi.org/10.25646/1376
local.edoc.container-titleEuroSurveillance
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20432
local.edoc.container-publisher-nameECDC
local.edoc.container-volume18
local.edoc.container-issue12
local.edoc.container-year2013

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