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2014-12-04Zeitschriftenartikel DOI: 10.1371/journal.pone.0113548
Low Rates of Antimicrobial-Resistant Enterobacteriaceae in Wildlife in Taï National Park, Côte d’Ivoire, Surrounded by Villages with High Prevalence of Multiresistant ESBL-Producing Escherichia coli in People and Domestic Animals
dc.contributor.authorAlbrechtova, Katerina
dc.contributor.authorPapousek, Ivo
dc.contributor.authorNys, Helene de
dc.contributor.authorPauly, Maude
dc.contributor.authorAnoh, Etile
dc.contributor.authorMossoun, Arsene
dc.contributor.authorDolejska, Monika
dc.contributor.authorMasarikova, Martina
dc.contributor.authorMetzger, Sonya
dc.contributor.authorCouacy-Hymann, Emmanuel
dc.contributor.authorAkoua-Koffi, Chantal
dc.contributor.authorWittig, Roman M.
dc.contributor.authorKlimes, Jiri
dc.contributor.authorCizek, Alois
dc.contributor.authorLeendertz, Fabian
dc.contributor.authorLiterak, Ivan
dc.date.accessioned2018-05-07T18:02:57Z
dc.date.available2018-05-07T18:02:57Z
dc.date.created2015-01-09
dc.date.issued2014-12-04none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/re2a0T3tqc9XM/PDF/28oM8qdIGjsSM.pdf
dc.identifier.urihttp://edoc.rki.de/176904/1999
dc.description.abstractAntimicrobial resistance genes can be found in all ecosystems, including those where antibiotic selective pressure has never been exerted. We investigated resistance genes in a collection of faecal samples of wildlife (non-human primates, mice), people and domestic animals (dogs, cats) in Côte d’Ivoire; in the chimpanzee research area of Taï National Park (TNP) and adjacent villages. Single bacteria isolates were collected from antibiotic-containing agar plates and subjected to molecular analysis to detect Enterobacteriaceae isolates with plasmid-mediated genes of extended-spectrum beta-lactamases (ESBLs) and plasmid-mediated quinolone resistance (PMQR). While the prevalence of ESBL-producing E. coli in the villages was 27% in people (n = 77) and 32% in dogs (n = 38), no ESBL-producer was found in wildlife of TNP (n = 75). PMQR genes, mainly represented by qnrS1, were also present in human- and dog-originating isolates from the villages (36% and 42% in people and dogs, respectively), but no qnrS has been found in the park. In TNP, different variants of qnrB were detected in Citrobacter freundii isolates originating non-human primates and mice. In conclusion, ESBL and PMQR genes frequently found in humans and domestic animals in the villages were rather exceptional in wildlife living in the protected area. Although people enter the park, the strict biosecurity levels they are obliged to follow probably impede transmission of bacteria between them and wildlife.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut
dc.subjectBacterialeng
dc.subjectAnimalseng
dc.subjectHumanseng
dc.subjectEscherichia coli/geneticseng
dc.subjectPrevalenceeng
dc.subjectDrug Resistance Multipleeng
dc.subjectEscherichia coli/drug effectseng
dc.subjectEscherichia coli Infections/microbiologyeng
dc.subjectbeta-Lactamases/geneticseng
dc.subjectBacterial Proteins/metabolismeng
dc.subjectBacterial Proteins/geneticseng
dc.subjectEscherichia coli Infections/epidemiologyeng
dc.subjectAnti-Bacterial Agents/pharmacologyeng
dc.subjectDogseng
dc.subjectMicrobial Sensitivity Testseng
dc.subjectbeta-Lactamases/metabolismeng
dc.subjectPlasmids/metabolismeng
dc.subjectCatseng
dc.subjectAnimals Domesticeng
dc.subjectAnimals Wild/microbiologyeng
dc.subjectCitrobacter freundii/geneticseng
dc.subjectCitrobacter freundii/isolation & purificationeng
dc.subjectCote d'Ivoireeng
dc.subjectEnterobacteriaceae/drug effectseng
dc.subjectEnterobacteriaceae/geneticseng
dc.subjectEnterobacteriaceae/isolation & purificationeng
dc.subjectEnterobacteriaceae Infections/epidemiologyeng
dc.subjectEnterobacteriaceae Infections/microbiologyeng
dc.subjectPlasmids/geneticseng
dc.subjectQuinolones/pharmacologyeng
dc.subject.ddc610 Medizin
dc.titleLow Rates of Antimicrobial-Resistant Enterobacteriaceae in Wildlife in Taï National Park, Côte d’Ivoire, Surrounded by Villages with High Prevalence of Multiresistant ESBL-Producing Escherichia coli in People and Domestic Animals
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10038378
dc.identifier.doi10.1371/journal.pone.0113548
dc.identifier.doihttp://dx.doi.org/10.25646/1924
local.edoc.container-titlePLoS ONE
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0113548
local.edoc.container-publisher-namePublic Library of Science
local.edoc.container-volume9
local.edoc.container-issue12
local.edoc.container-year2014

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