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2015-11-19Zeitschriftenartikel DOI: 10.2807/1560-7917.ES.2015.20.46.30067
Incidence of invasive meticillin-resistant Staphylococcus aureus infections in Germany, 2010 to 2014
dc.contributor.authorWalter, Jan
dc.contributor.authorHaller, Sebastian
dc.contributor.authorBlank, Hans-Peter
dc.contributor.authorEckmanns, Tim
dc.contributor.authorSin, Muna Abu
dc.contributor.authorHermes, Julia
dc.date.accessioned2018-05-07T18:36:23Z
dc.date.available2018-05-07T18:36:23Z
dc.date.created2015-11-25
dc.date.issued2015-11-19none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/reNiZnE7bJh6M/PDF/22P1XTSbnjm0M.pdf
dc.identifier.urihttp://edoc.rki.de/176904/2178
dc.description.abstractVoluntary surveillance systems in Germany suggest a recent decline in the incidence of infections (subsequent to at least 2010) with meticillin-resistant Staphylococcus aureus (MRSA) from various types of specimens and settings. We asked whether this decline is reflected by data from the mandatory national surveillance system for invasive MRSA infections. Our analysis is based on the population in Germany in 2010 to 2014. Cases were identified from passive reporting by microbiological laboratories of the diagnosis of MRSA from blood culture or cerebrospinal fluid. Respective clinical data were subsequently added to the notification. We calculated risk ratios (RR) between consecutive years, stratifying cases by sex, age and federal state of residence. The national incidence increased from 4.6 episodes per 100,000 persons in 2010 to 5.6 in 2012 (2011 vs 2010: RR: 1.13, 95% confidence interval (CI): 1.08–1.18; 2012 vs 2011: RR: 1.08, 95% CI: 1.04–1.13). It stagnated at 5.4 per 100,000 in 2013 (RR: 0.97, 95% CI: 0.93–1.01) before declining to 4.8 in 2014 (RR: 0.88, 95% CI: 0.84–0.91). This trend was observed in most, but not all federal states and strata of sex and age groups. Only 204 of 20,679 (1%) episodes of infection were notified as belonging to an outbreak. Our analysis corroborates previous findings that the incidence of invasive MRSA infections in Germany may be declining.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Infektionsepidemiologie
dc.subjectHumanseng
dc.subjectFemaleeng
dc.subjectMaleeng
dc.subjectAdolescenteng
dc.subjectGermany/epidemiologyeng
dc.subjectMiddle Agedeng
dc.subjectRisk Factorseng
dc.subjectAge Distributioneng
dc.subjectSex Distributioneng
dc.subjectPopulation Surveillance/methodseng
dc.subjectIncidenceeng
dc.subjectStaphylococcal Infections/microbiologyeng
dc.subjectStaphylococcal Infections/epidemiologyeng
dc.subjectPolymerase Chain Reactioneng
dc.subjectRetrospective Studieseng
dc.subjectCross Infection/microbiologyeng
dc.subjectCommunity-Acquired Infections/microbiologyeng
dc.subjectMethicillin-Resistant Staphylococcus aureus/isolation & purificationeng
dc.subjectCross Infection/epidemiologyeng
dc.subjectMethicillin Resistanceeng
dc.subjectMethicillin-Resistant Staphylococcus aureus/drug effectseng
dc.subjectBacteremia/epidemiologyeng
dc.subjectBacteremia/microbiologyeng
dc.subjectCommunity-Acquired Infections/epidemiologyeng
dc.subjectMandatory Programs/statistics & numerical dataeng
dc.subjectMandatory Programs/trendseng
dc.subjectMethicillin/pharmacologyeng
dc.subject.ddc610 Medizin
dc.titleIncidence of invasive meticillin-resistant Staphylococcus aureus infections in Germany, 2010 to 2014
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10041656
dc.identifier.doi10.2807/1560-7917.ES.2015.20.46.30067
dc.identifier.doihttp://dx.doi.org/10.25646/2103
local.edoc.container-titleEuroSurveillance
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=21306
local.edoc.container-publisher-nameECDC
local.edoc.container-volume20
local.edoc.container-issue46
local.edoc.container-year2015

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