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2015-12-10Zeitschriftenartikel DOI: 10.2807/1560-7917.ES.2015.20.49.30087
Tuberculosis treatment outcome in the European Union and European Economic Area: an analysis of surveillance data from 2002‒2011
dc.contributor.authorKaro, Basel
dc.contributor.authorHauer, Barbara
dc.contributor.authorHollo, V.
dc.contributor.authorWerf, Marieke van der
dc.contributor.authorFiebig, Lena
dc.contributor.authorHaas, Walter
dc.date.accessioned2018-05-07T18:42:04Z
dc.date.available2018-05-07T18:42:04Z
dc.date.created2015-12-18
dc.date.issued2015-12-10none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/reSnsYfDTaYS/PDF/25klKONol5PCk.pdf
dc.identifier.urihttp://edoc.rki.de/176904/2209
dc.description.abstractMonitoring the treatment outcome (TO) of tuberculosis (TB) is essential to evaluate the effectiveness of the intervention and to identify potential barriers for TB control. The global target is to reach a treatment success rate (TSR) of at least 85%. We aimed to assess the TB TO in the European Union and European Economic Area (EU/EEA) between 2002 and 2011, and to identify factors associated with unsuccessful treatment. Only 18 countries reported information on TO for the whole observation period accounting for 250,854 new culture-confirmed pulmonary TB cases. The 85% target of TSR was not reached in any year between 2002 and 2011 and was on average 78%. The TSR for multidrug-resistant (MDR)-TB cases at 24-month follow-up was 49%. In the multivariable regression model, unsuccessful treatment was significantly associated with increasing age (odds ratio (OR) = 1.02 per a one-year increase, 95% confidence interval (CI): 1.02–1.02), MDR-TB (OR = 8.7, 95% CI: 5.09–14.97), male sex (OR = 1.40, 95% CI: 1.28–1.52), and foreign origin (OR = 1.32, 95% CI: 1.03–1.70). The data highlight that special efforts are required for patients with MDR-TB and the elderly aged ≥65 years, who have particularly low TSR. To allow for valid monitoring at EU level all countries should aim to report TO for all TB cases.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Infektionsepidemiologie
dc.subject.ddc610 Medizin
dc.titleTuberculosis treatment outcome in the European Union and European Economic Area: an analysis of surveillance data from 2002‒2011
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10042315
dc.identifier.doi10.2807/1560-7917.ES.2015.20.49.30087
dc.identifier.doihttp://dx.doi.org/10.25646/2134
local.edoc.container-titleEuroSurveillance
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=21328
local.edoc.container-publisher-nameECDC
local.edoc.container-volume20
local.edoc.container-issue49
local.edoc.container-year2015

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