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2017-05-01Zeitschriftenartikel DOI: 10.1371/journal.pntd.0005570
External quality assessment study for ebolavirus PCR-diagnostic promotes international preparedness during the 2014 – 2016 Ebola outbreak in West Africa
dc.contributor.authorEllerbrok, Heinz
dc.contributor.authorJacobsen, Sonja
dc.contributor.authorPatel, Pranav
dc.contributor.authorRieger, Toni
dc.contributor.authorEickmann, Markus
dc.contributor.authorBecker, Stephan
dc.contributor.authorGünther, Stephan
dc.contributor.authorNaidoo, Dhamari
dc.contributor.authorSchrick, Livia
dc.contributor.authorKeeren, Kathrin
dc.contributor.authorTargosz, Angelina
dc.contributor.authorTeichmann, Anette
dc.contributor.authorFormenty, Pierre
dc.contributor.authorNiedrig, Matthias
dc.date.accessioned2018-05-07T20:11:51Z
dc.date.available2018-05-07T20:11:51Z
dc.date.created2017-07-07
dc.date.issued2017-05-01none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/reo3FJQL04FA/PDF/21G8oAFs8PyYo.pdf
dc.identifier.urihttp://edoc.rki.de/176904/2697
dc.description.abstractDuring the recent Ebola outbreak in West Africa several international mobile laboratories were deployed to the mainly affected countries Guinea, Sierra Leone and Liberia to provide ebolavirus diagnostic capacity. Additionally, imported cases and small outbreaks in other countries required global preparedness for Ebola diagnostics. Detection of viral RNA by reverse transcription polymerase chain reaction has proven effective for diagnosis of ebolavirus disease and several assays are available. However, reliability of these assays is largely unknown and requires serious evaluation. Therefore, a proficiency test panel of 11 samples was generated and distributed on a global scale. Panels were analyzed by 83 expert laboratories and 106 data sets were returned. From these 78 results were rated optimal and 3 acceptable, 25 indicated need for improvement. While performance of the laboratories deployed to West Africa was superior to the overall performance there was no significant difference between the different assays applied.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Biologische Sicherheit
dc.subject.ddc610 Medizin
dc.titleExternal quality assessment study for ebolavirus PCR-diagnostic promotes international preparedness during the 2014 – 2016 Ebola outbreak in West Africa
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10053298
dc.identifier.doi10.1371/journal.pntd.0005570
dc.identifier.doihttp://dx.doi.org/10.25646/2622
local.edoc.container-titlePLoS Neglected Tropical Diseases
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005570
local.edoc.container-volume11
local.edoc.container-issue5
local.edoc.container-year2017

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