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2017-09-18Zeitschriftenartikel DOI: 10.1186/s12985-017-0843-0
A novel Coltivirus-related virus isolated from free-tailed bats from Côte d’Ivoire is able to infect human cells in vitro
dc.contributor.authorWeiss, Sabrina
dc.contributor.authorDabrowski, Piotr Wojtek
dc.contributor.authorKurth, Andreas
dc.contributor.authorLeendertz, Siv Aina J.
dc.contributor.authorLeendertz, Fabian H.
dc.date.accessioned2018-05-07T20:38:53Z
dc.date.available2018-05-07T20:38:53Z
dc.date.created2017-10-05
dc.date.issued2017-09-18none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/reUJO3gxmQbBI/PDF/21gkf1v6SNuDE.pdf
dc.identifier.urihttp://edoc.rki.de/176904/2842
dc.description.abstractBackground: Zoonotic transmission events play a major role in the emergence of novel diseases. While such events are virtually impossible to predict, wildlife screening for potential emerging pathogens can be a first step. Driven by recent disease epidemics like severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and Ebola, bats have gained special interest as reservoirs of emerging viruses. Methods: As part of a bigger study investigating pathogens in African bats we screened animals for the presence of known and unknown viruses. Results: We isolated and characterised a novel reovirus from blood of free-tailed bats (Chaereophon aloysiisabaudiae) captured in 2006 in Côte d’Ivoire. The virus showed closest relationship with two human pathogenic viruses, Colorado tick fever virus and Eyach virus, and was able to infect various human cell lines in vitro. Conclusion: The study shows the presence of a coltivirus-related virus in bats from Sub-Sahara Africa. Serological studies could help to assess its impact on humans or wildlife health.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut
dc.subject.ddc610 Medizin
dc.titleA novel Coltivirus-related virus isolated from free-tailed bats from Côte d’Ivoire is able to infect human cells in vitro
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10055279
dc.identifier.doi10.1186/s12985-017-0843-0
dc.identifier.doihttp://dx.doi.org/10.25646/2767
local.edoc.container-titleVirology Journal
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://virologyj.biomedcentral.com/articles/10.1186/s12985-017-0843-0
local.edoc.container-publisher-nameBioMedCentral
local.edoc.container-volume14
local.edoc.container-issue181
local.edoc.container-year2017

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