2022-01-05Zeitschriftenartikel
Emergence of methicillin resistance predates the clinical use of antibiotics
Larsen, Jesper; Raisen, Claire L.; Ba, Xiaoliang; Sadgrove, Nicholas J.; Padilla-González, Guillermo F.; Simmonds, Monique S.J.; Loncaric, Igor; Kerschner, Heidrun; Apfalter, Petra; Hartl, Rainer; Deplano, Ariane; Vendendriessche, Stien; Černá Bolfíková, Barbora; Hulva, Pavel; Arendrup, Maiken C.; Hare, Rasmus K.; Barnadas, Céline; Stegger, Marc; Sieber, Raphael N.; Skov, Robert L.; Petersen, Andreas; Angen, Øystein; Rasmussen, Sophie L.; Espinosa-Gongora, Carmen; Aarestrup, Frank M.; Lindholm, Laura J.; Nykäsenoja, Suvi M.; Laurent, Frederic; Becker, Karsten; Walther, Birgit; Kehrenberg, Corinna; Cuny, Christiane; Layer, Franziska; Werner, Guido; Witte, Wolfgang; Stamm, Ivonne; Moroni, Paolo; Jørgensen, Hannah J.; de Lencastre, Hermínia; Cercenado, Emilia; García-Garrote, Fernando; Börjesson, Stefan; Hæggman, Sara; Perreten, Vincent; Teale, Christopher J.; Waller, Andrew S.; Pichon, Bruno; Curran, Martin D.; Ellington, Matthew J.; Welch, John J.; Peacock, Sharon J.; Seilly, David J.; Morgan, Fiona J.E.; Parkhill, Julian; Hadjirin, Nazreen F.; Lindsay, Jodi A.; Holden, Matthew T.G.; Edwards, Giles F.; Foster, Geoffrey; Paterson, Gavin K.; Didelot, Xavier; Holmes, Mark A.; Harrison, Ewan M.; Larsen, Anders R.
The discovery of antibiotics more than 80 years ago has led to considerable improvements in human and animal health. Although antibiotic resistance in environmental bacteria is ancient, resistance in human pathogens is ...