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Browsing Artikel in Fachzeitschriften by Author "Dauber, Bianca"
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2009-10-27ZeitschriftenartikelActivation of the Antiviral Kinase PKR and Viral Countermeasures Dauber, Bianca; Wolff, ThorstenThe interferon-induced double-stranded (ds)RNA-dependent protein kinase (PKR) limits viral replication by an eIF2-mediated block of translation. Although many negative-strand RNA viruses activate PKR, the responsible ...
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2008-11-05ZeitschriftenartikelAnalysis of influenza B virus NS1 protein trafficking reveals a novel interaction with nuclear speckle domains Schneider, Jana; Dauber, Bianca; Melén, Krister; Julkunen, Ilkka; Wolff, ThorstenMany proteins that function in the transcription, maturation, and export of metazoan mRNAs are concentrated in nuclear speckle domains, indicating that the compartment is important for gene expression. Here, we show that ...
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2009-06-12ZeitschriftenartikelInfluenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR Dauber, Bianca; Martinez-Sobrido, Luis; Schneider, Jana; Hai, Rong; Waibler, Zoe; Kalinke, Ulrich; Garcis-Sastre, Adolfo; Wolff, ThorstenActivation of the latent kinase PKR is a potent innate defense reaction of vertebrate cells towards viral infections, which is triggered by recognition of viral double-stranded (ds) RNA and results in a translational ...
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2011-09-14ZeitschriftenartikelInfluenza B Virus With Modified Hemagglutinin Cleavage Site as a Novel Attenuated Live Vaccine Stech, Jürgen; Garn, Holger; Herwig, Astrid; Stech, Olga; Dauber, Bianca; Wolff, Thorsten; Mettenleiter, Thomas C.; Klenk, Hans-DieterBackground: Both pandemic and interpandemic influenza is associated with high morbidity and mortality worldwide. Seasonal epidemics are caused by both influenza A and B virus strains that cocirculate with varying predominance ...