Browsing Artikel in Fachzeitschriften by Author "Palacios, Gustavo F."

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2024-01-08Zeitschriftenartikel

Peripheral immune responses to filoviruses in a reservoir versus spillover hosts reveal transcriptional correlates of disease

Guito, Jonathan C.; Arnold, Catherine E.; Schuh, Amy J.; Amman, Brian R.; Sealy, Tara K.; Spengler, Jessica R.; Harmon, Jessica R.; Coleman-McCray, Joann D.; Sanchez-Lockhart, Mariano; Palacios, Gustavo F.; Towner, Jonathan S.; Prescott, Joseph B.

Several filoviruses, including Marburg virus (MARV), cause severe disease in humans and nonhuman primates (NHPs). However, the Egyptian rousette bat (ERB, Rousettus aegyptiacus), the only known MARV reservoir, shows no ...
2019-12-04Zeitschriftenartikel

Rousette Bat Dendritic Cells Overcome Marburg Virus-Mediated Antiviral Responses by Upregulation of Interferon-Related Genes While Downregulating Proinflammatory Disease Mediators

Prescott, Joseph; Guito, Jonathan C.; Spengler, Jessica R.; Arnold, Catherine E.; Schuh, Amy J.; Amman, Brian R.; Sealy, Tara K.; Guerrero, Lisa W.; Palacios, Gustavo F.; Sanchez-Lockhart, Mariano; Albariño, Cesar G.; Towner, Jonathan S.

Dysregulated and maladaptive immune responses are at the forefront of human diseases caused by infection with zoonotic viral hemorrhagic fever viruses. Elucidating mechanisms of how the natural animal reservoirs of these ...