Browsing Artikel in Fachzeitschriften by Author "Bachem, Annabell"

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2012-07-18Zeitschriftenartikel

Expression of XCR1 characterizes the Batf3-dependent lineage of dendritic cells capable of antigen cross-presentation

Bachem, Annabell; Hartung, Evelyn; Güttler, Steffen; Mora, Ahmed; Zhou, Xuefei; Hegemann, Anika; Plantinga, Maud; Mazzini, Elisa; Stoitzner, Patrizia; Gurka, Stephanie; Henn, Volker; Mages, Hans Werner; Kroczek, Richard

Cross-presentation of antigen by dendritic cells (DCs) to CD8+ T cells is a fundamentally important mechanism in the defense against pathogens and tumors. Due to the lack of an appropriate lineage marker, cross-presenting ...
2014-07-28Zeitschriftenartikel

Ontogenic, phenotypic, and functional characterization of XCR1+ dendritic cells leads to a consistent classification of intestinal dendritic cells based on the expression of XCR1 and SIRPα

Becker, Martina; Güttler, Steffen; Bachem, Annabell; Hartung, Evelyn; Mora, Ahmed; Jäkel, Anika; Hutloff, Andreas; Henn, Volker; Mages, Hans Werner; Gurka, Stephanie; Kroczek, Richard

In the past, lack of lineage markers confounded the classification of dendritic cells (DC) in the intestine and impeded a full understanding of their location and function. We have recently shown that the chemokine receptor ...
2010-05-17Zeitschriftenartikel

Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells

Bachem, Annabell; Güttler, Steffen; Hartung, Evelyn; Ebstein, Frédéric; Schaefer, Michael; Tannert, Astrid; Salama, Abdulgabar; Movassaghi, Kamran; Opitz, Corinna; Mages, Hans Werner; Henn, Volker; Kloetzel, Peter-Michael; Gurka, Stephanie; Kroczek, Richard

In recent years, human dendritic cells (DCs) could be subdivided into CD304+ plasmacytoid DCs (pDCs) and conventional DCs (cDCs), the latter encompassing the CD1c+, CD16+, and CD141+ DC subsets. To date, the low frequency ...