Browsing Artikel in Fachzeitschriften by Author "van Dooren, Giel G."

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2021-08-25Zeitschriftenartikel

Coordinated action of multiple transporters in the acquisition of essential cationic amino acids by the intracellular parasite Toxoplasma gondii

Fairweather, Stephen J.; Rajendran, Esther; Blume, Martin; Javed, Kiran; Steinhöfel, Birte; McConville, Malcolm J.; Kirk, Kiaran; Bröer, Stefan; van Dooren, Giel G.

Intracellular parasites of the phylum Apicomplexa are dependent on the scavenging of essential amino acids from their hosts. We previously identified a large family of apicomplexan-specific plasma membrane-localized amino ...
2019-02-11Zeitschriftenartikel

The tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family

Parker, Kathryn E. R.; Fairweather, Stephen J.; Rajendran, Esther; Blume, Martin; McConville, Malcolm J.; Bröer, Stefan; Kirk, Kiaran; van Dooren, Giel G.

Apicomplexan parasites are auxotrophic for a range of amino acids which must be salvaged from their host cells, either through direct uptake or degradation of host proteins. Here, we describe a family of plasma membrane-localized ...