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Browsing Artikel in Fachzeitschriften by Author "Brown, Richard J. P."
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2016-05-24ZeitschriftenartikelIn vivo evidence for ribavirin-induced mutagenesis of the hepatitis E virus genome Todt, Daniel; Gisa, Anett; Radonic, Aleksandar; Nitsche, Andreas; Behrendt, Patrick; Suneetha, Pothakamuri Venkata; Pischke, Sven; Bremer, Birgit; Brown, Richard J. P.; Manns, Michael P.; Cornberg, Markus; Bock, Thomas; Steinmann, Eike; Wedemeyer, HeinerObjective: Hepatitis E virus (HEV) infection can take chronic courses in immunocompromised patients potentially leading to liver cirrhosis and liver failure. Ribavirin (RBV) is currently the only treatment option for many ...
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2022-02-02ZeitschriftenartikelIntra-host analysis of hepaciviral glycoprotein evolution reveals signatures associated with viral persistence and clearance Gömer, André; Brown, Richard J. P.; Pfaender, Stephanie; Deterding, Katja; Reuter, Gábor; Orton, Richard; Seitz, Stefan; Bock, C.- Thomas; Cavalleri, Jessika M. V.; Pietschmann, Thomas; Wedemeyer, Heiner; Steinmann, Eike; Todt, DanielEven 30 years after the discovery of the hepatitis C virus (HCV) in humans there is still no vaccine available. Reasons for this include the high mutation rate of HCV, which allows the virus to escape immune recognition ...