Artikel in Fachzeitschriften: Recent submissions
Now showing items 221-240 of 4474
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2024-07-09ZeitschriftenartikelClinical and genomic features of Mycobacterium avium complex: a multi-national European study Background: The Mycobacterium avium complex (MAC) comprises the most frequent non-tuberculous mycobacteria (NTM) in Central Europe and currently includes twelve species. M. avium (MAV), M. intracellulare subsp. ...
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2024-01-25ZeitschriftenartikelReported antibiotic use among patients in the multicenter ANDEMIA infectious diseases surveillance study in sub-saharan Africa Background: Exposure to antibiotics has been shown to be one of the drivers of antimicrobial resistance (AMR) and is critical to address when planning and implementing strategies for combatting AMR. However, data on ...
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2024-08-06ZeitschriftenartikelNormal Values for the fT3/fT4 Ratio: Centile Charts (0–29 Years) and Their Application for the Differential Diagnosis of Children with Developmental Delay Primary congenital hypothyroidism is easily diagnosed on the basis of elevated plasma levels of thyroid-stimulating hormone (TSH). In contrast, in the rare disorders of thyroid hormone resistance, TSH and, in mild cases, ...
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2024-06-06ZeitschriftenartikelGenetic determinants of host- and virus-derived insertions for hepatitis E virus replication Hepatitis E virus (HEV) is a long-neglected RNA virus and the major causative agent of acute viral hepatitis in humans. Recent data suggest that HEV has a very heterogeneous hypervariable region (HVR), which can tolerate ...
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2024-01-15ZeitschriftenartikelImplementation of the WHO core components of an infection prevention and control programme in two sub-saharan African acute health-care facilities: a mixed methods study Background: The coronavirus pandemic again highlighted the need for robust health care facility infection prevention and control (IPC) programmes. WHO guidelines on the core components (CCs) of IPC programmes provides ...
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2024-12-03ZeitschriftenartikelImpfverhalten von Klinikpersonal verstehen – Ergebnisse der OKaPII-Studie 2023 Hintergrund: Das Potenzial der Influenza-Impfung zur Verhinderung der Erkrankung und Weiterverbreitung des Virus wird im klinischen Setting nicht ausgeschöpft. Ein Verständnis von Impfverhalten ist notwendig, um wirksame ...
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2024-05-12ZeitschriftenartikelThe gut microbiome, resistome, and mycobiome in preterm newborn infants and mouse pups: lack of lasting effects by antimicrobial therapy or probiotic prophylaxis Background: Enhancing our understanding of the underlying influences of medical interventions on the microbiome, resistome and mycobiome of preterm born infants holds significant potential for advancing infection ...
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2024-03-20ZeitschriftenartikelGerman coasts harbor non-O1/non-O139 Vibrio cholerae with clinical virulence gene profiles Non-O1/non-O139 Vibrio cholerae (NOVC) are ubiquitous in aquatic ecosystems. In rare cases, they can cause intestinal and extra-intestinal infections in human. This ability is associated with various virulence factors. The ...
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2024-06-14ZeitschriftenartikelCervical cancer trend in the Republic of Kazakhstan and attitudes towards cervical cancer screening in urban and rural areas Cervical cancer (CC) continues to be a significant global health issue, which in part can be attributed to disparities in access to CC screening services. This study aims to conduct a trend of CC in Kazakhstan and to compare ...
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2024-08-29ZeitschriftenartikelCombining RNA Interference and RIG-I Activation to Inhibit Hepatitis E Virus Replication Hepatitis E virus (HEV) poses a significant global health threat, with an estimated 20 million infections occurring annually. Despite being a self-limiting illness, in most cases, HEV infection can lead to severe outcomes, ...
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2024-01-10ZeitschriftenartikelImpact of ACE I gene insertion/deletion, A-240T polymorphisms and the renin–angiotensin–aldosterone system on COVID-19 disease Background: The coronavirus disease 2019 (COVID-19) pandemic is driven by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which has led to an enormous burden on patient morbidity and mortality. ...
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2024-02-11ZeitschriftenartikelDifferent metabolic adaptation strategies after overwintering in Eutrema sp. and Arabidopsis accessions under field conditions in Germany Successful overwintering is a prerequisite for high fitness in temperate perennials and winter annuals and is highly dependent on increased freezing tolerance and timely balancing of deacclimation with growth resumption ...
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2024-07-12ZeitschriftenartikelgNOMO2: a comprehensive and modular pipeline for integrated multi-omics analyses of microbiomes Background: In recent years, omics technologies have offered an exceptional chance to gain a deeper insight into the structural and functional characteristics of microbial communities. As a result, there is a growing ...
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2024-08-08ZeitschriftenartikelImpact of reference design on estimating SARS-CoV-2 lineage abundances from wastewater sequencing data Background: Sequencing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA from wastewater samples has emerged as a valuable tool for detecting the presence and relative abundances of SARS-CoV-2 variants ...
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2024-01-19ZeitschriftenartikeltANCHOR cell-based ELISA approach as a surrogate for antigen-coated plates to monitor specific IgG directed to the SARS-CoV-2 receptor-binding domain Enzyme-linked immunosorbent assay (ELISA) systems use plates coated with peptides or expressed and purified proteins to monitor immunoglobulins derived from patient serum. However, there is currently no easy, flexible, and ...
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2024-12-23ZeitschriftenartikelEnd-to-end simulation of nanopore sequencing signals with feed-forward transformers Motivation: Nanopore sequencing represents a significant advancement in genomics, enabling direct long-read DNA sequencing at the single-molecule level. Accurate simulation of nanopore sequencing signals from nucleotide ...
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2024-11-05ZeitschriftenartikelAssociation between Socioeconomic Position of the Family and Adolescent Obesity in Germany—Analysis of the Mediating Role of Familial Determinants Background: Obesity’s negative impact on young people’s health has long been known. The family and its socioeconomic position (SEP) are key determinants in adolescent obesity. However, understanding which familial determinants ...
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2024-01-18ZeitschriftenartikelA look at staphylococci from the one health perspective Staphylococcus aureus and other staphylococcal species are resident and transient multihost colonizers as well as conditional pathogens. Especially S. aureus represents an excellent model bacterium for the “One Health” ...
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2024-02-13ZeitschriftenartikelOutpatient Health Service Utilization Among Adults with Diabetes, Hypertension and Cardiovascular Disease During the COVID-19 Pandemic – Results of Population-Based Surveys in Germany from 2019 to 2021 Purpose: Fear of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and lockdown measures may have an impact on health care utilization particularly for people with chronic diseases. We investigated ...
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2024-07-30ZeitschriftenartikelA nested model for AI design and validation The growing AI field faces trust, transparency, fairness, and discrimination challenges. Despite the need for new regulations, there is a mismatch between regulatory science and AI, preventing a consistent framework. A ...