Artikel in Fachzeitschriften: Recent submissions
Now showing items 2621-2640 of 3542
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2012-05-04ZeitschriftenartikelAssessment of the human medical significance of the rabies zoonosis in Germany – analysis of available data and desiderata Abschätzung der humanmedizinischen Bedeutung der Zoonose Tollwut in Deutschland – Analyse der verfügbaren Daten und DesiderateUm die humanmedizinische Bedeutung der Zoonose Tollwut in Deutschland abzuschätzen, wurden für die Jahre 2006–2010 Daten der einschlägigen „Surveillance“ und des Meldewesens sowie die in der gesetzlichen Krankenversicherung ...
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2012-05-31ZeitschriftenartikelProspective hospital-based case–control study to assess the effectiveness of pandemic influenza A(H1N1)pdm09 vaccination and risk factors for hospitalization in 2009–2010 using matched hospital and test-negative controls Background: We performed a case–control study to estimate vaccine effectiveness (VE) for prevention of hospitalization due to pandemic influenza A(H1N1)pdm09 (pH1N1) and to identify risk factors for pH1N1 and acute ...
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2012-08-31ZeitschriftenartikelMetagenomic abundance estimation and diagnostic testing on species level One goal of sequencing-based metagenomic community analysis is the quantitative taxonomic assessment of microbial community compositions. In particular, relative quantification of taxons is of high relevance for metagenomic ...
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2012-08-30ZeitschriftenartikelEvidence for airborne infectious disease transmission in public ground transport – a literature review While guidelines on contact tracing (CT) after exposure to certain infectious pathogens during air travel exist, no guidance documents are available on CT in response to potential exposure on public ground transport. We ...
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2012-01-30ZeitschriftenartikelEmergence of OXA-48-type carbapenemase-producing Enterobacteriaceae in German hospitals Nine carbapenem-resistant Enterobacteriaceae isolates collected from eight patients in five German hospitals were investigated. Six isolates produced the OXA-48 carbapenemase, and three isolates produced OXA-162, which is ...
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2011-05-10ZeitschriftenartikelNeue Empfehlungen für die Umgebungsuntersuchungen bei Tuberkulose Nach der Einführung der neuen Interferon-γ-Release Assays (IGRAs) in den Empfehlungen des Deutschen Zentralkomitees zur Bekämpfung der Tuberkulose im Jahre 2007 hat sich die Datenlage für deren Einsatz beträchtlich verbessert. ...
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2012-01-18ZeitschriftenartikelEvaluation of adding a second marker to overcome Staphylococcus aureus spa-typing homoplasies The utility of sequencing a second highly variable locus in addition to the spa gene (e.g., double-locus sequence typing [DLST]) was investigated to overcome limitations of a Staphylococcus aureus single-locus typing method. ...
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2011-12-09ZeitschriftenartikelAbsence of Livestock-Associated Methicillin-Resistant Staphylococcus aureus Clonal Complex CC398 as a Nasal Colonizer of Pigs Raised in an Alternative System Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) ST398 isolated from pigs raised in conventional farms was previously reported. Here we report a study on 25 farms adhering to an alternative system. ...
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2011-05-31ZeitschriftenartikelImprovement of H5N1 influenza vaccine viruses: Influence of internal gene segments of avian and human origin on production and hemagglutinin content The H5N1-clade 1 influenza vaccine strain NIBRG-14 produces exceptionally low amounts of antigen, a problem recently encountered also for initial pandemic H1N1-2009 vaccine seeds. Here, we report on a strategy that may ...
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2011-11-30ZeitschriftenartikelGenome analysis of bat adenovirus 2: Indications of interspecies transmission The genome of bat adenovirus 2 was sequenced and analyzed. It is similar in size (31,616 bp) to the genomes of bat adenovirus 3 and canine adenoviruses 1 and 2. These four viruses are monophyletic and share an identical ...
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2011-05-30ZeitschriftenartikelApplication of a split luciferase complementation assay for the detection of viral protein–protein interactions Intraviral protein-protein interactions are critical for virus survival in the host. Discovery of such interactions is important to understand molecular mechanisms of viral replication and pathogenesis. The development of ...
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2011-05-25ZeitschriftenartikelPopulation-wide use of behavioural prevention and counselling programmes for lifestyle-related cardiovascular risk factors in Germany Background: Behavioural prevention and counselling programmes for lifestyle-related cardiovascular risk factors are widely offered. However, their population-wide use is largely unexplored, particularly in high-risk persons ...
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2011-06-21ZeitschriftenartikelMolecular characterization of blaNDM-1 in an Acinetobacter baumannii strain isolated in Germany in 2007 Objectives: To investigate the genetic environment of the metallo-β-lactamase gene blaNDM-1 in an Acinetobacter baumannii isolated in 2007 in a German hospital. Methods: Antimicrobial susceptibility testing was performed ...
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2011-06-01ZeitschriftenartikelRNA helicase retinoic acid-inducible gene I as a sensor of Hantaan virus replication Hantaan virus (HTNV) causes severe human disease. The HTNV genome consists of three ssRNA segments of negative polarity that are complexed with viral nucleocapsid (N) protein. How the human innate immune system detects ...
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2012-05-23ZeitschriftenartikelChromosomal Aberrations Associated with Clonal Evolution and Leukemic Transformation in Fanconi Anemia: Clinical and Biological Implications Fanconi anaemia (FA) is an inherited disease with congenital and developmental abnormalities, bone marrow failure, and extreme risk of leukemic transformation. Bone marrow surveillance is an important part of the clinical ...
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2012-07-18ZeitschriftenartikelExpression of XCR1 characterizes the Batf3-dependent lineage of dendritic cells capable of antigen cross-presentation Cross-presentation of antigen by dendritic cells (DCs) to CD8+ T cells is a fundamentally important mechanism in the defense against pathogens and tumors. Due to the lack of an appropriate lineage marker, cross-presenting ...
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2012-08-03ZeitschriftenartikelThe role of the mycobacterial DNA-binding protein 1 (MDP1) from Mycobacterium bovis BCG in host cell interaction Background: Mycobacterium tuberculosis differs from most pathogens in its ability to multiply inside monocytes and to persist during long periods of time within granuloma in a status of latency. A class of proteins ...
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2012-06-19ZeitschriftenartikelHautkrebs – Epidemiologie und Früherkennung
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2012-09-01ZeitschriftenartikelHenipavirus-related Sequences in Fruit Bat Bushmeat, Republic of Congo TO THE EDITOR: Bats are hosts for various emerging viruses, including the zoonotic paramyxoviruses Hendra virus and Nipah virus, which occur in Australia and Southeast Asia, respectively, and cause severe disease outbreaks ...
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2012-09-01ZeitschriftenartikelEffectiveness and Timing of Vaccination during School Measles Outbreak Despite high vaccination coverage in most European countries, large community outbreaks of measles do occur, normally clustered around schools and resulting from suboptimal vaccination coverage. To determine whether or ...