Artikel in Fachzeitschriften: Recent submissions
Now showing items 361-380 of 3855
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2021-03-11ZeitschriftenartikelIdentification of two novel hepatitis C virus subtype 2 from Tunisia (2v and 2w) Background Hepatitis C virus (HCV) has a high genetic diversity. Eight genotypes and 90 subtypes are currently described. Genotypes are clinically significant for therapeutic management and their determination is necessary ...
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2021-11-22ZeitschriftenartikelThe Redox Homeostasis of Skeletal Muscle Cells Regulates Stage Differentiation of Toxoplasma gondii Toxoplasma gondii is an obligatory intracellular parasite that causes persistent infections in birds and mammals including ~30% of the world’s human population. Differentiation from proliferative and metabolically active ...
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2021-09-10ZeitschriftenartikelInferring gene regulatory networks from single-cell RNA-seq temporal snapshot data requires higher-order moments Single-cell RNA sequencing (scRNA-seq) has become ubiquitous in biology. Recently, there has been a push for using scRNA-seq snapshot data to infer the underlying gene regulatory networks (GRNs) steering cellular function. ...
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2021-11-04ZeitschriftenartikelEstablishment of a specimen panel for the decentralised technical evaluation of the sensitivity of 31 rapid diagnostic tests for SARS-CoV-2 antigen, Germany, September 2020 to April 2021 Introduction The detection of SARS-CoV-2 with rapid diagnostic tests (RDT) has become an important tool to identify infected people and break infection chains. These RDT are usually based on antigen detection in a lateral ...
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2021-04-22ZeitschriftenartikelGenetic diversity and pathogenic potential of Shiga toxin-producing Escherichia coli (STEC) derived from German flour Shiga toxin-producing Escherichia coli (STEC) can cause severe human illness, which are frequently linked to the consumption of contaminated beef or dairy products. However, recent outbreaks associated with contaminated ...
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2021-04-01ZeitschriftenartikelEpidemiological, clinical, and public health response characteristics of a large outbreak of diphtheria among the Rohingya population in Cox’s Bazar, Bangladesh, 2017 to 2019: A retrospective study Background Unrest in Myanmar in August 2017 resulted in the movement of over 700,000 Rohingya refugees to overcrowded camps in Cox’s Bazar, Bangladesh. A large outbreak of diphtheria subsequently began in this ...
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2021-05-28ZeitschriftenartikelRegAB Homolog of Burkholderia pseudomallei is the Master Regulator of Redox Control and involved in Virulence Burkholderia pseudomallei, the etiological agent of melioidosis in humans and animals, often occupies environmental niches and infection sites characterized by limited concentrations of oxygen. Versatile genomic features ...
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2021-01-29ZeitschriftenartikelRicin Antibodies’ Neutralizing Capacity against Different Ricin Isoforms and Cultivars Ricin, a highly toxic protein from Ricinus communis, is considered a potential biowarfare agent. Despite the many data available, no specific treatment has yet been approved. Due to their ability to provide immediate ...
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2021-09-17ZeitschriftenartikelTracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch (updated) Late in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of biological concern were reported, one in the United Kingdom and one in South Africa. Using ...
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2021-09-16ZeitschriftenartikelSupporting National Immunization Technical Advisory Groups in the WHO European Region in developing national COVID-19 vaccination recommendations through online communication platform National Immunization Technical Advisory Groups are groups of multi-disciplinary experts that provide scientific advice to policy makers to enable them to make informed immunization policy and programme decisions. NITAGs ...
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2021-11-17ZeitschriftenartikelA Comprehensive Analysis of Human Endogenous Retroviruses HERV-K (HML.2) from Teratocarcinoma Cell Lines and Detection of Viral Cargo in Microvesicles About 8% of our genome is composed of sequences from Human Endogenous Retroviruses (HERVs). The HERV-K (HML.2) family, here abbreviated HML.2, is able to produce virus particles that were detected in cell lines, malignant ...
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2021-03-05ZeitschriftenartikelHigh Prevalence of Carbapenemase-Producing Acinetobacter baumannii in Wound Infections, Ghana, 2017/2018 Three years after a prospective study on wound infections in a rural hospital in Ghana revealed no emergence of carbapenem-resistant bacteria we initiated a new study to assess the prevalence of multidrug-resistant pathogens. ...
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2021-08-16ZeitschriftenartikelDiagnostic performance of capillary and venous blood samples in the detection of Loa loa and Mansonella perstans microfilaraemia using light microscopy Background Loa loa and Mansonella perstans–the causative agents of loiasis and mansonellosis—are vector-borne filarial parasites co-endemic in sub-Saharan Africa. Diagnosis of both infections is usually established by ...
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2021-11-05ZeitschriftenartikelNeue Therapiealgorithmen: COVID-19 von leicht bis schwer richtig behandeln Diese COVRIIN-Handlungs- empfehlungen sollen behan- delnden Ärzten eine prakti- sche Hilfestellung für alltägliche Entscheidungen in der Klinik sein. Sie sind als lebendes Dokument zu verstehen und unter www.rki.de ...
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2021-03-15ZeitschriftenartikelChanges in the prevalence of self-reported sexually transmitted bacterial infections from 2010 and 2017 in two large European samples of men having sex with men–is it time to re-evaluate STI-screening as a control strategy? Background/Objectives Many European countries reported increased numbers of syphilis, gonorrhoea and chlamydia diagnoses among men who have sex with men (MSM) in recent years. Behaviour changes and increased testing are ...
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2021-10-12ZeitschriftenartikelKnock-In Mice Expressing a 15-Lipoxygenating Alox5 Mutant Respond Differently to Experimental Inflammation Than Reported Alox5−/− Mice Arachidonic acid 5-lipoxygenase (ALOX5) is the key enzyme in the biosynthesis of pro- inflammatory leukotrienes. We recently created knock-in mice (Alox5-KI) which express an arachi- donic acid 15-lipoxygenating Alox5 ...
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2021-10-24ZeitschriftenartikelMolecular surveillance and genetic divergence of rotavirus A antigenic epitopes in Gabonese children with acute gastroenteritis Background Rotavirus A (RVA) causes acute gastroenteritis in children <5 years of age in sub-Saharan Africa. In this study, we described the epidemiology and genetic diversity of RVA infecting Gabonese children and ...
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2021-08-05ZeitschriftenartikelToward a Common Performance and Effectiveness Terminology for Digital Proximity Tracing Applications Digital proximity tracing (DPT) for Sars-CoV-2 pandemic mitigation is a complex intervention with the primary goal to notify app users about possible risk exposures to infected persons. DPT not only relies on the technical ...
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2021-10-08ZeitschriftenartikelCross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination INTRODUCTION The clinical manifestations of COVID-19 vary from asymptomatic infection to respiratory failure. Severe disease courses are primarily associated with advanced age, immune dysfunctions, and comorbidities. ...
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2021-01-13ZeitschriftenartikelDevelopment and Evaluation of an Immuno-MALDI-TOF Mass Spectrometry Approach for Quantification of the Abrin Toxin in Complex Food Matrices The toxin abrin found in the seeds of Abrus precatorius has attracted much attention regarding criminal and terroristic misuse over the past decade. Progress in analytical methods for a rapid and unambiguous identification ...