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2009-11-01Zeitschriftenartikel DOI: 10.25646/439
Epidemiology of Hepatitis A Virus Infections, 2007-2008
dc.contributor.authorFaber, Mirko
dc.contributor.authorStark, Klaus
dc.contributor.authorBehnke, Susanne
dc.contributor.authorSchreier, Eckart
dc.contributor.authorFrank, Christina
dc.date.accessioned2018-05-07T13:29:31Z
dc.date.available2018-05-07T13:29:31Z
dc.date.created2009-12-11
dc.date.issued2009-11-01none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/rehUY4FD42h3U/PDF/242hBrqklAu4s.pdf
dc.identifier.urihttp://edoc.rki.de/176904/514
dc.description.abstractApproximately 60% of hepatitis A virus infections in Germany occur in persons without a travel history to disease-endemic areas and for whom sources of infection are unknown. Recommendation of pretravel vaccination fails to prevent the remaining imported infections. Using enhanced surveillance in 2007–2008, we analyzed epidemiologic patterns of hepatitis A in Germany and appropriateness and adequacy of current immunization recommendations. Young patients with a migration background who had visited friends and family in their ancestral countries accounted for most imported cases. Phylogenetic analysis showed high diversity of sequence data and clustering of strains with similar regions of origin or patient migration backgrounds. Virologic findings are compatible with those of low-incidence countries, where virtually all infections are directly or indirectly imported from other regions. Germans with a migration background are seen as a special risk group so far insufficiently reached by pretravel vaccination advice.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Infektionsepidemiologie
dc.subjectAdolescenteng
dc.subjectPreschooleng
dc.subjectDNAeng
dc.subjectHumanseng
dc.subjectPhylogenyeng
dc.subjectFemaleeng
dc.subjectTraveleng
dc.subjectGermany/epidemiologyeng
dc.subjectMaleeng
dc.subjectMiddle Agedeng
dc.subjectHepatitis A/epidemiologyeng
dc.subjectRisk Factorseng
dc.subjectRNAeng
dc.subjectChildeng
dc.subjectAdulteng
dc.subjectViral/bloodeng
dc.subjectAgedeng
dc.subjectInfanteng
dc.subjectBase Sequenceeng
dc.subjectViral/geneticseng
dc.subjectHepatitis A virus/geneticseng
dc.subjectEmigrants and Immigrantseng
dc.subjectEmigration and Immigrationeng
dc.subjectYoung Adulteng
dc.subjectDNA Primers/geneticseng
dc.subjectHepatitis A/prevention & controleng
dc.subjectHepatitis A/virologyeng
dc.subjectHepatitis A virus/classificationeng
dc.subjectMolecular Epidemiologyeng
dc.subject.ddc610 Medizin
dc.titleEpidemiology of Hepatitis A Virus Infections, 2007-2008
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-1003364
dc.identifier.doihttp://dx.doi.org/10.25646/439
local.edoc.container-titleEmerging Infectious Diseases
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://www.cdc.gov/eid/content/15/11/1760.htm
local.edoc.container-publisher-nameCenters for Disease Control and Prevention
local.edoc.container-volume15
local.edoc.container-issue11
local.edoc.container-year2009

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