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2007-05-30Zeitschriftenartikel DOI: 10.1038/sj.ejcn.1602825
Vitamin D status and health correlates among German adults
dc.contributor.authorHintzpeter, Birte
dc.contributor.authorMensink, Gert
dc.contributor.authorThierfelder, Wulf
dc.contributor.authorMüller, MJ
dc.contributor.authorScheidt-Nave, Christa
dc.date.accessioned2018-05-07T13:36:25Z
dc.date.available2018-05-07T13:36:25Z
dc.date.created2010-01-21
dc.date.issued2007-05-30none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/reGS6a10JyrfQ/PDF/28YQqqpHEDzg2.pdf
dc.identifier.urihttp://edoc.rki.de/176904/551
dc.description.abstractObjective: To analyze vitamin D status based on serum 25-hydroxyvitamin D (25OHD) measurements, its determinants and health correlates in a representative sample of German adults. Subjects: A total of 1763 men and 2267 women, 18- to 79-year old, who participated in the representative German National Health Interview and Examination Survey 1998 and the integrated German Nutrition Survey. Results: The median vitamin D intake from both diet and supplements did not meet the recommended level of 5 microg/day, in either men (2.8 microg/day) or women (2.3 microg/day). Altogether 80.9% of men and 88.5% of women had vitamin D intakes below this level. Moderate (12.5-25 nmol/l serum 25OHD levels) and mild (25-50 nmol/l) vitamin D deficiency was prevalent in the adult population in Germany, even in younger age groups. Overall, 57% of men and 58% of women had vitamin D levels below 50 nmol/l. Among 65- to 79-year-old women, the proportion amounted to 75%, even during the sunnier half of the year. In sex-specific multiple linear regression models, independent determinants of serum 25OHD levels consistently included season, vitamin D intake from both diet and supplements, physical activity and living in a partnership. In addition, age and current menopausal hormone use contributed to the model among women, as opposed to time of day of blood sampling and body mass index (marginally) among men. Significantly lower serum 25OHD levels were observed in women with hypertension, cardiovascular diseases and noninsulin-treated diabetes mellitus as well as in men with insulin-treated diabetes mellitus compared with nonaffected participants. Conclusions: Vitamin D deficiency is a public health issue in Germany. We identified a number of determinants with potential for primary prevention of vitamin D deficiency. Risk and benefits of preventive actions need to be examined in further studies.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut; Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
dc.subjectAdolescenteng
dc.subjectHumanseng
dc.subjectFemaleeng
dc.subjectGermany/epidemiologyeng
dc.subjectMaleeng
dc.subjectMiddle Agedeng
dc.subjectBody Mass Indexeng
dc.subjectRisk Factorseng
dc.subjectAdulteng
dc.subjectAgedeng
dc.subjectSeasonseng
dc.subjectVitamin D Deficiency/epidemiologyeng
dc.subjectLinear Modelseng
dc.subjectNutrition Surveyseng
dc.subjectNutritional Statuseng
dc.subjectYoung Adulteng
dc.subjectCalcium/bloodeng
dc.subjectDietary Supplementseng
dc.subjectParathyroid Hormone/bloodeng
dc.subjectVitamin D/analogs & derivativeseng
dc.subjectVitamin D/bloodeng
dc.subjectVitamin D Deficiency/complicationseng
dc.subjectVitamin D Deficiency/prevention & controleng
dc.subject.ddc610 Medizin
dc.titleVitamin D status and health correlates among German adults
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-1004050
dc.identifier.doi10.1038/sj.ejcn.1602825
dc.identifier.doihttp://dx.doi.org/10.25646/476
local.edoc.container-titleEuropean Journal of Clinical Nutrition
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://www.nature.com/ejcn/journal/v62/n9/abs/1602825a.html
local.edoc.container-publisher-nameNature
local.edoc.container-volume62
local.edoc.container-issue9
local.edoc.container-year2007

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