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2019-03-13Zeitschriftenartikel DOI: 10.25646/6031
Hepatitis E virus (HEV)—The Future
dc.contributor.authorDenner, Joachim
dc.date.accessioned2019-03-29T08:20:38Z
dc.date.available2019-03-29T08:20:38Z
dc.date.issued2019-03-13none
dc.identifier.other10.3390/v11030251
dc.identifier.urihttp://edoc.rki.de/176904/6066
dc.description.abstractHepatitis (HEV) is widely distributed in pigs and is transmitted with increasing numbers to humans by contact with pigs, contaminated food and blood transfusion. The virus is mostly apathogenic in pigs but may enhance the pathogenicity of other pig viruses. In humans, infection can lead to acute and chronic hepatitis and extrahepatic manifestations. In order to stop the emerging infection, effective counter-measures are required. First of all, transmission by blood products can be prevented by screening all blood donations. Meat and sausages should be appropriately cooked. Elimination of the virus from the entire pork production can be achieved by sensitive testing and elimination programs including early weaning, colostrum deprivation, Caesarean delivery, embryo transfer, treatment with antivirals, protection from de novo infection, and possibly vaccination. In addition, contaminated water, shellfish, vegetables, and fruits by HEV-contaminated manure should be avoided. A special situation is given in xenotransplantation using pig cells, tissues or organs in order to alleviate the lack of human transplants. The elimination of HEV from pigs, other animals and humans is consistent with the One Health concept, preventing subclinical infections in the animals as well as preventing transmission to humans and disease.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjecthepatitis E viruseng
dc.subjecthepatitiseng
dc.subjectblood donationseng
dc.subjectelimination programseng
dc.subjectemerging diseaseseng
dc.subjectone healtheng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleHepatitis E virus (HEV)—The Futurenone
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:0257-176904/6066-8
dc.identifier.doihttp://dx.doi.org/10.25646/6031
dc.type.versionpublishedVersionnone
local.edoc.container-titleVirusesnone
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://www.mdpi.com/1999-4915/11/3/251none
local.edoc.container-publisher-nameMultidisciplinary Digital Publishing Institutenone
local.edoc.container-volume11none
local.edoc.container-issue3none
local.edoc.container-reportyear2019none
local.edoc.container-year2019none
local.edoc.container-firstpage1none
local.edoc.container-lastpage11none
local.edoc.rki-departmentInfektionskrankheitennone
dc.description.versionPeer Reviewednone

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