No evidence of carbapenemase-producing Enterobacteriaceae in stool samples of 1,544 asylum seekers arriving in Rhineland-Palatinate, Germany, April 2016 to March, 2017
dc.contributor.author | Ehlkes, Lutz | |
dc.contributor.author | Pfeifer, Yvonne | |
dc.contributor.author | Werner, Guido | |
dc.contributor.author | Ignatius, Ralf | |
dc.contributor.author | Vogt, Manfred | |
dc.contributor.author | Eckmanns, Tim | |
dc.contributor.author | Zanger, Philipp | |
dc.contributor.author | Walter, Jan | |
dc.date.accessioned | 2019-04-26T11:16:13Z | |
dc.date.available | 2019-04-26T11:16:13Z | |
dc.date.issued | 2019-02-21 | none |
dc.identifier.other | 10.2807/1560-7917.ES.2019.24.8.1800030 | |
dc.identifier.uri | http://edoc.rki.de/176904/6146 | |
dc.description.abstract | Introduction: Since 2015, increased migration from Asia and Africa to Europe has raised public health concerns about potential importation of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE), specifically those producing carbapenemases (C-PE), into European hospitals. Aims: To inform infection control practices about ESBL-PE prevalence in asylum seekers and to investigate whether C-PE prevalence exceeds that in the German population. Methods: Cross-sectional study from April 2016–March 2017. Routinely collected stool samples from asylum seekers were tested for antibiotic resistant Enterobacteriaceae. Country/region of origin and demographic characteristics were explored as risk factors for faecal colonisation. Results: Of 1,544 individuals, 294 tested positive for ESBL-PE colonisation (19.0%; 95% confidence intervals (CI): 17.0–21.0). Asylum seekers originating from Afghanistan/Pakistan/Iran had a prevalence of 29.3% (95% CI: 25.6–33.2), from Syria 20.4% (95% CI: 16.1–25.2) and from Eritrea/Somalia 11.9% (95% CI: 8.7–15.7). CTX-M-15 (79%) and CTX-M-27 (10%) were the most common ESBL determinants. Highest ESBL-PE prevalences were observed in boys under 10 years and women aged 20–39 years (interaction: p = 0.03). No individuals tested positive for C-PE. Faecal C-PE colonisation prevalence in asylum seekers was not statistically significantly different from prevalence reported in German communities. Conclusion: In absence of other risk factors, being a newly arrived asylum seeker from a region with increased faecal ESBL-PE colonisation prevalence is not an indicator for C-PE colonisation and thus not a reason for pre-emptive screening and isolation upon hospital admission. | eng |
dc.language.iso | eng | none |
dc.publisher | Robert Koch-Institut | |
dc.rights | (CC BY 3.0 DE) Namensnennung 3.0 Deutschland | ger |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/de/ | |
dc.subject | Afghanistan | eng |
dc.subject | E. coli ST131 | eng |
dc.subject | ESBL | eng |
dc.subject | beta-lactamase CTX-M-27 | eng |
dc.subject | Eritrea | eng |
dc.subject | Escherichia coli | eng |
dc.subject | Iran | eng |
dc.subject | Pakistan | eng |
dc.subject | Somalia | eng |
dc.subject | Syria | eng |
dc.subject | beta-lactamase CTX-M-15 | eng |
dc.subject | carbapenem-resistant Enterobacteriaceae | eng |
dc.subject | communicable diseases | eng |
dc.subject | cross-sectional studies | eng |
dc.subject | drug resistance | eng |
dc.subject | emerging | eng |
dc.subject | epidemiology | eng |
dc.subject | human migration | eng |
dc.subject | infectious disease transmission | eng |
dc.subject | mass screening | eng |
dc.subject | microbial | eng |
dc.subject | plasmid mediated fluoroquinolone resistance | eng |
dc.subject | prevalence | eng |
dc.subject | refugees | eng |
dc.subject.ddc | 610 Medizin und Gesundheit | none |
dc.title | No evidence of carbapenemase-producing Enterobacteriaceae in stool samples of 1,544 asylum seekers arriving in Rhineland-Palatinate, Germany, April 2016 to March, 2017 | none |
dc.type | article | |
dc.identifier.urn | urn:nbn:de:kobv:0257-176904/6146-2 | |
dc.identifier.doi | http://dx.doi.org/10.25646/6118 | |
dc.type.version | publishedVersion | none |
local.edoc.container-title | Eurosurveillance | none |
local.edoc.type-name | Zeitschriftenartikel | |
local.edoc.container-type | periodical | |
local.edoc.container-type-name | Zeitschrift | |
local.edoc.container-url | https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2019.24.8.1800030#abstract_content | none |
local.edoc.container-publisher-name | Institut de Veille Sanitaire | none |
local.edoc.container-volume | 24 | none |
local.edoc.container-issue | 8 | none |
local.edoc.container-reportyear | 2019 | none |
local.edoc.container-year | 2019 | none |
local.edoc.container-firstpage | 1 | none |
local.edoc.container-lastpage | 9 | none |
local.edoc.rki-department | Infektionsepidemiologie | none |
dc.description.version | Peer Reviewed | none |