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2019-05-16Zeitschriftenartikel DOI: 10.25646/6246
Elevated neopterin levels in wild, healthy chimpanzees indicate constant investment in unspecific immune system
dc.contributor.authorBehringer, Verena
dc.contributor.authorStevens, Jeroen M. G.
dc.contributor.authorWittig, Roman M.
dc.contributor.authorCrockford, Catherine
dc.contributor.authorZuberbühler, Klaus
dc.contributor.authorLeendertz, Fabian H.
dc.contributor.authorDeschner, Tobias
dc.date.accessioned2019-09-04T11:25:31Z
dc.date.available2019-09-04T11:25:31Z
dc.date.issued2019-05-16none
dc.identifier.other10.1186/s40850-019-0041-1
dc.identifier.urihttp://edoc.rki.de/176904/6264
dc.description.abstractBackground Ecological immunology proposes that the optimal immune defence, and the costs coming with it, vary across environments. In environments with higher pathogen load, the immune system should experience greater challenges and, therefore, investment in maintaining it should be higher. The biomarker neopterin allows monitoring of innate immune responses, and is therefore an ideal tool to investigate the effects of ecological variables on the immune system. Here, we compared urinary neopterin levels of apparently healthy chimpanzees without acute symptoms of sickness across two environments: in captivity (22 zoos) and in the wild (two populations). Results Our results revealed that urinary neopterin levels were nearly twice as high in wild compared to captive chimpanzees, independent of chimpanzee subspecies. Conclusion We conclude that wild chimpanzees experience more frequent immune challenges in comparison to captive individuals. Therefore, wild individuals have to allocate more energy to immune function and away from reproduction and growth. Our data indicate that the generally delayed development of wild animals in comparison to captive individuals might not only be related to lower energy intake but might result from greater energy allocations to immune function. Finally, our data highlight the importance of understanding immune costs for accurate characterization of energy budgets in animals.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectEcoimmunologyeng
dc.subjectImmune responseeng
dc.subjectEnergy allocationeng
dc.subjectCostseng
dc.subjectCaptive and wild livingeng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleElevated neopterin levels in wild, healthy chimpanzees indicate constant investment in unspecific immune systemnone
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:0257-176904/6264-7
dc.identifier.doihttp://dx.doi.org/10.25646/6246
dc.type.versionpublishedVersionnone
local.edoc.container-titleBMC Zoologynone
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://bmczool.biomedcentral.com/articles/10.1186/s40850-019-0041-1#Abs1none
local.edoc.container-publisher-nameBioMed Centralnone
local.edoc.container-volume4none
local.edoc.container-issue2none
local.edoc.container-reportyear2019none
local.edoc.container-year2019none
local.edoc.container-firstpage1none
local.edoc.container-lastpage7none
local.edoc.rki-departmentProjektgruppen/Nachwuchsgruppennone
dc.description.versionPeer Reviewednone

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