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2020-04-03Zeitschriftenartikel DOI: 10.25646/6930
Monitoring Antimicrobial Resistance and Drug Usage in the Human and Livestock Sector and Foodborne Antimicrobial Resistance in Six European Countries
dc.contributor.authorMesa Varona, Octavio
dc.contributor.authorChaintarli, Katerina
dc.contributor.authorMuller-Pebody, Berit
dc.contributor.authorAnjum, Muna F.
dc.contributor.authorEckmanns, Tim
dc.contributor.authorNorström, Madelaine
dc.contributor.authorBoone, Ides
dc.contributor.authorTenhagen, Bernd-Alois
dc.date.accessioned2020-05-28T13:09:27Z
dc.date.available2020-05-28T13:09:27Z
dc.date.issued2020-04-03none
dc.identifier.other10.2147/IDR.S237038
dc.identifier.urihttp://edoc.rki.de/176904/6816
dc.description.abstractIntroduction: Antimicrobial resistance (AMR), associated with antimicrobial use (AMU), is a major public concern. Surveillance and monitoring systems are essential to assess and control the trends in AMU and AMR. However, differences in the surveillance and monitoring systems between countries and sectors make comparisons challenging. The purpose of this article is to describe all surveillance and monitoring systems for AMU and AMR in the human and livestock sectors, as well as national surveillance and monitoring systems for AMR in food, in six European countries (Spain, Germany, France, the Netherlands, the United Kingdom and Norway) as a baseline for developing suggestions to overcome current limitations in comparing AMU and AMR data. Methods: A literature search in 2018 was performed to identify relevant peer-reviewed articles and national and European grey reports as well as AMU/AMR databases. Results: Comparison of AMU and AMR systems across the six countries showed a lack of standardization and harmonization with different AMU data sources (prescription vs sales data) and units of AMU and AMR being used. The AMR data varied by sample type (clinical/non-clinical), laboratory method (disk diffusion, microdilution, and VITEK, among others), data type, ie quantitative (minimum inhibition concentration (MIC) in mg/L/inhibition zone (IZ) in mm) vs qualitative data (susceptible-intermediate-resistant (SIR)), the standards used (EUCAST/CLSI among others), and/or the evaluation criteria adopted (epidemiological or clinical). Discussion: A One Health approach for AMU and AMR requires harmonization in various aspects between human, animal and food systems at national and international levels. Additionally, some overlap between systems of AMU and AMR has been encountered. Efforts should be made to improve standardization and harmonization and allow more meaningful analyses of AMR and AMU surveillance data under a One Health approach.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectAMReng
dc.subjectAMUeng
dc.subjectfood-producing animalseng
dc.subjectharmonizationeng
dc.subjectmonitoringeng
dc.subjectsurveillanceeng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleMonitoring Antimicrobial Resistance and Drug Usage in the Human and Livestock Sector and Foodborne Antimicrobial Resistance in Six European Countriesnone
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:0257-176904/6816-4
dc.identifier.doihttp://dx.doi.org/10.25646/6930
dc.type.versionpublishedVersionnone
local.edoc.container-titleInfection and Drug Resistancenone
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://www.dovepress.com/monitoring-antimicrobial-resistance-and-drug-usage-in-the-human-and-li-peer-reviewed-article-IDRnone
local.edoc.container-publisher-nameDovepressnone
local.edoc.container-volume2020none
local.edoc.container-issue13none
local.edoc.container-year2020none
local.edoc.container-firstpage957none
local.edoc.container-lastpage993none
local.edoc.rki-departmentInfektionsepidemiologienone
dc.description.versionPeer Reviewednone

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