Zur Kurzanzeige

2021-04-20Zeitschriftenartikel
Bugs That Can Resist Antibiotics but Not Men: Gender-Specific Differences in Notified Infections and Colonisations in Germany, 2010–2019
dc.contributor.authorBrandl, Michael
dc.contributor.authorHoffmann, Alexandra
dc.contributor.authorWillrich, Niklas
dc.contributor.authorReuss, Annicka
dc.contributor.authorReichert, Felix
dc.contributor.authorWalter, Jan
dc.contributor.authorEckmanns, Tim
dc.contributor.authorHaller, Sebastian
dc.date.accessioned2022-02-01T10:24:15Z
dc.date.available2022-02-01T10:24:15Z
dc.date.issued2021-04-20none
dc.identifier.other10.3390/microorganisms9050894
dc.identifier.urihttp://edoc.rki.de/176904/9311
dc.description.abstractData from surveillance networks show that men have a higher incidence rate of infections with anti-microbial-resistant (AMR) pathogens than women. We systematically analysed data of infections and colonisations with AMR pathogens under mandatory surveillance in Germany to quantify gender-specific differences. We calculated incidence-rates (IR) per 100,000 person–years for invasive infections with Methicillin-resistant Staphylococcus aureus (MRSA), and for infections or colonisations with carbapenem-non-susceptible Acinetobacter spp. (CRA), and Enterobacterales (CRE), using the entire German population as a denominator. We limited the study periods to years with complete notification data (MRSA: 2010–2019, CRA/CRE: 2017–2019). We used Poisson regression to adjust for gender, age group, federal state, and year of notification. In the study periods, IR for all notifications were 4.2 for MRSA, 0.90 for CRA, and 4.8 for CRE per 100,000 person-–years. The adjusted IR ratio for infections of men compared to women was 2.3 (95% confidence interval [CI]: 2.2–2.3) for MRSA, 2.2 (95%CI: 1.9–2.7) for CRA, and 1.7 (95%CI: 1.6–1.8) for CRE. Men in Germany show about double the risk for infection with AMR pathogens than women. This was also true for colonisations, where data were available. Screening procedures and associated hygiene measures may profit from a gender-stratified approach.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectantimicrobial resistanceeng
dc.subjectgender distributioneng
dc.subjectmethicillin-resistant Staphylococcus aureuseng
dc.subjectcarbapenem-non-susceptible Enterobacteraleseng
dc.subjectcarbapenem-non-susceptible Acinetobactereng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleBugs That Can Resist Antibiotics but Not Men: Gender-Specific Differences in Notified Infections and Colonisations in Germany, 2010–2019none
dc.typearticle
dc.identifier.urnurn:nbn:de:0257-176904/9311-7
dc.type.versionpublishedVersionnone
local.edoc.container-titleMicroorganismsnone
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://www.mdpi.com/2076-2607/9/5/894none
local.edoc.container-publisher-nameMDPInone
local.edoc.container-volume9none
local.edoc.container-issue5none
local.edoc.container-year2021none
local.edoc.container-firstpage1none
local.edoc.container-lastpage10none
local.edoc.rki-departmentInfektionsepidemiologienone
dc.description.versionPeer Reviewednone

Zur Kurzanzeige