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2020-10-06ZeitschriftenartikelExpression of in vivo biotinylated recombinant antigens SAG1 and SAG2A from Toxoplasma gondii for improved seroepidemiological bead-based multiplex assays Background Few bead-based multiplex assays have been described that detect antibodies against the protozoan parasite Toxoplasma gondii in large-scale seroepidemiological surveys. Moreover, each multiplex assay has ...
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2020-09-08ZeitschriftenartikelSilence as a way of niche adaptation: mecC-MRSA with variations in the accessory gene regulator (agr) functionality express kaleidoscopic phenotypes Functionality of the accessory gene regulator (agr) quorum sensing system is an important factor promoting either acute or chronic infections by the notorious opportunistic human and veterinary pathogen Staphylococcus ...
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2020-11-16ZeitschriftenartikelHealth-related quality of life in children and adolescents with overweight and obesity: results from the German KIGGS survey Background The well-being of persons with overweight and obesity, in particular of children and adolescents, may be impaired. The present study investigates the health-related quality of life (HRQoL) of girls and boys ...
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2020-10-16ZeitschriftenartikelImpact of porcine cytomegalovirus on long‑term orthotopic cardiac xenotransplant survival Xenotransplantation using pig organs has achieved survival times up to 195 days in pig orthotopic heart transplantation into baboons. Here we demonstrate that in addition to an improved immunosuppressive regimen, non-ischaemic ...
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2021-03-17ZeitschriftenartikelHunting and consumption of rodents by children in the Lassa fever endemic area of Faranah, Guinea As a consequence of the Ebola outbreak, human–animal contact has gained importance for zoonotic transmission surveillance. In Faranah (Upper Guinea), daily life is intertwined with rodents, such as the Natal multimammate ...
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2021-01-29ZeitschriftenartikelUtility of a Sequence-Independent, Single-Primer-Amplification (SISPA) and Nanopore Sequencing Approach for Detection and Characterization of Tick-Borne Viral Pathogens Currently, next generation sequencing (NGS) is the mainly used approach for identification and monitorization of viruses with a potential public health threat in clinical and environmental samples. To facilitate detection ...
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2021-01-27ZeitschriftenartikelHematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis) Laboratory-controlled physiological data for the multimammate rat (Mastomys natalensis) are scarce, despite this species being a known reservoir and vector for zoonotic viruses, including the highly pathogenic Lassa virus, ...
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2021-02-15ZeitschriftenartikelGenome-Wide Association Studies for the Detection of Genetic Variants Associated With Daptomycin and Ceftaroline Resistance in Staphylococcus aureus Background: As next generation sequencing (NGS) technologies have experienced a rapid development over the last decade, the investigation of the bacterial genetic architecture reveals a high potential to dissect causal ...
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2021-02-01ZeitschriftenartikelInterpretable detection of novel human viruses from genome sequencing data Viruses evolve extremely quickly, so reliable meth- ods for viral host prediction are necessary to safe- guard biosecurity and biosafety alike. Novel human- infecting viruses are difficult to detect with stan- dard ...
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2021-01-19ZeitschriftenartikelGenome-Based Analyses of Fitness Effects and Compensatory Changes Associated with Acquisition of blaCMY-, blaCTX-M-, and blaOXA-48/VIM-1-Containing Plasmids in Escherichia coli Background: Resistance plasmids are under selective conditions beneficial for the bacterial host, but in the absence of selective pressure, this carriage may cause fitness costs. Compensation of this fitness burden is ...
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2021-01-15ZeitschriftenartikelCryptococcus bacillisporus (VGIII) Meningoencephalitis Acquired in Santa Cruz, Bolivia We describe a case of chronic meningoencephalitis with hydrocephalus caused by Crypto- coccus bacillisporus (VGIII) in an immunocompetent patient from Santa Cruz, Bolivia. This first report of a member of the Cryptococcus ...
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2020-11-12ZeitschriftenartikelSimplified Bioprinting-Based 3D Cell Culture Infection Models for Virus Detection Studies of virus–host interactions in vitro may be hindered by biological characteristics of conventional monolayer cell cultures that differ from in vivo infection. Three-dimensional (3D) cell cultures show more in vivo-like ...
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2022-02-03DatensatzTagesdaten-CSV aus dem DIVI-Intensivregister 2022-01-31Die Tagesdaten-CSV entspricht einem Auszug der Daten des DIVI-Intensivregisters. Die Datei enthält eine Aggregation der aktuellsten Meldungen pro Landkreis. Es werden die aktuell gemeldeten Anzahlen der COVID-19 Intensivfälle ...
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2022-02-03Berichte und sonstige TexteTagesreport aus dem DIVI-Intensivregister 2022-01-31Im Tagesreport werden täglich aktuelle Kennzahlen aus dem DIVI-Intensivregister (www.intensivregister.de) berichtet. Es werden die aktuell gemeldeten Anzahlen der COVID-19 Intensivfälle sowie die gemeldeten intensivmedizinischen ...
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2022-02-03DatensatzTagesdaten-CSV aus dem DIVI-Intensivregister 2022-01-30Die Tagesdaten-CSV entspricht einem Auszug der Daten des DIVI-Intensivregisters. Die Datei enthält eine Aggregation der aktuellsten Meldungen pro Landkreis. Es werden die aktuell gemeldeten Anzahlen der COVID-19 Intensivfälle ...
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2022-02-03Berichte und sonstige TexteTagesreport aus dem DIVI-Intensivregister 2022-01-30Im Tagesreport werden täglich aktuelle Kennzahlen aus dem DIVI-Intensivregister (www.intensivregister.de) berichtet. Es werden die aktuell gemeldeten Anzahlen der COVID-19 Intensivfälle sowie die gemeldeten intensivmedizinischen ...
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2022-02-03Berichte und sonstige TexteTagesreport aus dem DIVI-Intensivregister 2022-01-29Im Tagesreport werden täglich aktuelle Kennzahlen aus dem DIVI-Intensivregister (www.intensivregister.de) berichtet. Es werden die aktuell gemeldeten Anzahlen der COVID-19 Intensivfälle sowie die gemeldeten intensivmedizinischen ...
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2022-02-03DatensatzTagesdaten-CSV aus dem DIVI-Intensivregister 2022-01-29Die Tagesdaten-CSV entspricht einem Auszug der Daten des DIVI-Intensivregisters. Die Datei enthält eine Aggregation der aktuellsten Meldungen pro Landkreis. Es werden die aktuell gemeldeten Anzahlen der COVID-19 Intensivfälle ...
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2022-01-28Berichte und sonstige TexteGrippeWeb-Wochenbericht Kalenderwoche 3 (17.1. – 23.1.2022), Datenstand: 25.1.2022
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2021-05-25ZeitschriftenartikelNipah Virus Efficiently Replicates in Human Smooth Muscle Cells without Cytopathic Effect Nipah virus (NiV) is a highly pathogenic zoonotic virus with a broad species tropism, originating in pteropid bats. Human outbreaks of NiV disease occur almost annually, often with high case-fatality rates. The specific ...