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Auflistung nach Autor "Corman, Victor M."
Anzeige der Publikationen 1-12 von 12
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2022-02-02ZeitschriftenartikelAdvanced sequencing approaches detected insertions of viral and human origin in the viral genome of chronic hepatitis E virus patients Papp, C.‑Patrick; Biedermann, Paula; Harms, Dominik; Wang, Bo; Kebelmann, Marianne; Choi, Mira; Helmuth, Johannes; Corman, Victor M.; Thürmer, Andrea; Altmann, Britta; Klink, Patrycja; Hofmann, Jörg; Bock, C.‑ThomasThe awareness of hepatitis E virus (HEV) increased significantly in the last decade due to its unexpectedly high prevalence in high-income countries. There, infections with HEV-genotype 3 (HEV-3) are predominant which can ...
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2016-05-13ZeitschriftenartikelAn RNA-dependent RNA polymerase gene in bat genomes derived from an ancient negative-strand RNA virus Horie, Masayuki; Kobayashi, Yuki; Honda, Tomoyuki; Fujino, Kan; Akasaka, Takumi; Kohl, Claudia; Wibbelt, Gudrun; Mühldorfer, Kristin; Kurth, Andreas; Müller, Marcel A.; Corman, Victor M.; Gillich, Nadine; Suzuki, Yoshiyuki; Schwemmle, Martin; Tomonaga, KeizoEndogenous bornavirus-like L (EBLL) elements are inheritable sequences derived from ancient bornavirus L genes that encode a viral RNA-dependent RNA polymerase (RdRp) in many eukaryotic genomes. Here, we demonstrate that ...
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2021-10-08ZeitschriftenartikelCross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination Loyal, Lucie; Braun, Julian; Henze, Larissa; Kruse, Beate; Dingeldey, Manuela; Reimer, Ulf; Kern, Florian; Schwarz, Tatjana; Mangold, Maike; Unger, Clara; Dörfler, Friederike; Kadler, Shirin; Rosowski, Jennifer; Gürcan, Kübrah; Uyar-Aydin, Zehra; Frentsch, Marco; Kurth, Florian; Schnatbbaum, Karsten; Eckey, Maren; Hippenstiel, Stefan; Hocke, Andreas; Müller, Marcel A.; Sawitzki, Birgit; Miltenyi, Stefan; Paul, Friedemann; Mall, Marcus A.; Wenschuh, Holger; Voigt, Sebastian; Drosten, Christian; Lauster, Roland; Lachman, Nils; Sander, Leif-Erik; Corman, Victor M.; Röhmel, Jobst; Meyer-Arndt, Lil; Thiel, Andreas; Giesecke-Thiel, ClaudiaINTRODUCTION The clinical manifestations of COVID-19 vary from asymptomatic infection to respiratory failure. Severe disease courses are primarily associated with advanced age, immune dysfunctions, and comorbidities. ...
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2023-02-11ZeitschriftenartikelDistinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19 Mothes, Ronja; Pascual-Reguant, Anna; Koehler, Ralf; Liebeskind, Juliane; Liebheit, Alina; Bauherr, Sandy; Philipsen, Lars; Dittmayer, Carsten; Laue, Michael; von Manitius, Regina; Elezkurtaj, Sefer; Durek, Pawel; Heinrich, Frederik; Heinz, Gitta A.; Guerra, Gabriela M.; Obermayer, Benedikt; Meinhardt, Jenny; Ihlow, Jana; Radke, Josefine; Heppner, Frank L.; Enghard, Philipp; Stockmann, Helena; Aschman, Tom; Schneider, Julia; Corman, Victor M.; Sander, Leif E.; Mashreghi, Mir-Farzin; Conrad, Thomas; Hocke, Andreas C.; Niesner, Raluca A.; Radbruch, Helena; Hauser, Anja E.Prolonged lung pathology has been associated with COVID-19, yet the cellular and molecular mechanisms behind this chronic inflammatory disease are poorly understood. In this study, we combine advanced imaging and spatial ...
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2021-11-04ZeitschriftenartikelEstablishment of a specimen panel for the decentralised technical evaluation of the sensitivity of 31 rapid diagnostic tests for SARS-CoV-2 antigen, Germany, September 2020 to April 2021 Puyskens, Andreas; Krause, Eva; Michel, Janine; Nübling, C. Micha; Scheiblauer, Heinrich; Bourquain, Daniel; Grossegesse, Marica; Valusenko, Roman; Corman, Victor M.; Drosten, Christian; Zwirglmaier, Katrin; Wölfel, Roman; Lange, Constanze; Kramer, Jan; Friesen, Johannes; Ignatius, Ralf; Müller, Michael; Schmidt-Chanasit, Jonas; Emmerich, Petra; Schaade, Lars; Nitsche, AndreasIntroduction The detection of SARS-CoV-2 with rapid diagnostic tests (RDT) has become an important tool to identify infected people and break infection chains. These RDT are usually based on antigen detection in a lateral ...
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2015-05-30ZeitschriftenartikelFirst international external quality assessment of molecular diagnostics for Mers-CoV Pas, Suzan D.; Patel, Pranav; Reusken, Chantal; Domingo, Cristina; Corman, Victor M.; Drosten, Christian; Dijkman, Ronald; Thiel, Volker; Nowotny, Norbert; Koopmans, Marion P.G.; Niedrig, MatthiasBackground: Since the discovery of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012, diagnostic protocols were quickly published and deployed globally. Objectives: We set out to assess the quality of ...
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2021-09-07ZeitschriftenartikelFunctional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5 Schroeder, Simon; Christin, Mache; Kleine-Weber, Hannah; Corman, Victor M.; Muth, Doreen; Richter, Anja; Fatykhova, Diana; Memish, Ziad A.; Stanifer, Megan L.; Boulant, Steeve; Gultom, Mitra; Dijkman, Ronald; Eggeling, Stephan; Hocke, Andreas; Hippenstiel, Stefan; Thiel, Volker; Pöhlmann, Stefan; Wolff, Thorsten; Müller, Marcel A.; Drosten, ChristianMiddle East respiratory syndrome coronavirus (MERS-CoV) is enzootic in dromedary camels across the Middle East and Africa. Virus-induced pneumonia in humans results from animal contact, with a potential for limited onward ...
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2018-06-27ZeitschriftenartikelHuman coronavirus OC43 outbreak in wild chimpanzees, Côte d´Ivoire, 2016 Patrono, Livia V.; Samuni, Liran; Corman, Victor M.; Nourifar, Leila; Röthemeier, Caroline; Wittig, Roman M.; Drosten, Christian; Calvignac-Spencer, Sébastien; Leendertz, Fabian H.
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2023-04-02ZeitschriftenartikelMonitoring the SARS-CoV-2 Pandemic: Prevalence of Antibodies in a Large, Repetitive Cross-Sectional Study of Blood Donors in Germany—Results from the SeBluCo Study 2020–2022 Offergeld, Ruth; Preußel, Karina; Zeiler, Thomas; Aurich, Konstanze; Baumann-Baretti, Barbara I.; Ciesek, Sandra; Corman, Victor M.; Dienst, Viktoria; Drosten, Christian; Görg, Siegfried; Greinacher, Andreas; Grossegesse, Marica; Haller, Sebastian; Heuft, Hans-Gert; Hofmann, Natalie; Horn, Peter A.; Houareau, Claudia; Gülec, Ilay; Jiménez Klingberg, Carlos Luis; Juhl, David; Lindemann, Monika; Martin, Silke; Neuhauser, Hannelore K.; Nitsche, Andreas; Ohme, Julia; Peine, Sven; Sachs, Ulrich J.; Schaade, Lars; Schäfer, Richard; Scheiblauer, Heinrich; Schlaud, Martin; Schmidt, Michael; Umhau, Markus; Vollmer, Tanja; Wagner, Franz F.; Wieler, Lothar H.; Wilking, Hendrik; Ziemann, Malte; Zimmermann, Marlow; an der Heiden, MatthiasSARS-CoV-2 serosurveillance is important to adapt infection control measures and estimate the degree of underreporting. Blood donor samples can be used as a proxy for the healthy adult population. In a repeated cross-sectional ...
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2022-11-16ZeitschriftenartikelSARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B.1 strain in human cells with low ACE2 expression Niemeyer, Daniela; Stenzel, Saskia; Veith, Talitha; Schroeder, Simon; Friedmann, Kirstin; Weege, Friederike; Trimpert, Jakob; Heinze, Julian; Richter, Anja; Jansen, Jenny; Emanuel, Jackson; Kazmierski, Julia; Pott, Fabian; Jeworowski, Lara M.; Olmer, Ruth; Jaboreck, Mark-Christian; Tenner, Beate; Papies, Jan; Walper, Felix; Schmidt, Marie L.; Heinemann, Nicolas; Möncke-Buchner, Elisabeth; Baumgardt, Morris; Hoffmann, Karen; Widera, Marek; Thao, Tran Thi Nhu; Balázs, Anita; Schulze, Jessica; Mache, Christin; Jones, Terry Carleton; Morkel, Markus; Ciesek, Sandra; Hanitsch, Leif G.; Mall, Markus A.; Hocke, Andreas C.; Thiel, Volker; Osterrieder, Klaus; Wolff, Thorsten; Martin, Ulrich; Corman, Victor M.; Müller, Marcel A.; Goffinet, Christine; Drosten, ChristianEpidemiological data demonstrate that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) Alpha and Delta are more transmissible, infectious, and pathogenic than previous variants. ...
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2020-11-26ZeitschriftenartikelSerology- and PCR-based cumulative incidence of SARS-CoV-2 infection in adults in a successfully contained early hotspot (CoMoLo study), Germany, May to June 2020 Santos-Hövener, Claudia; Neuhauser, Hannelore K.; Schaffrath Rosario, Angelika; Busch, Markus; Schlaud, Martin; Hoffmann, Robert; Gößwald, Antje; Koschollek, Carmen; Hoebel, Jens; Allen, Jennifer; Haack-Erdmann, Antje; Brockmann, Stefan; Ziese, Thomas; Nitsche, Andreas; Michel, Janine; Haller, Sebastian; Wilking, Hendrik; Hamouda, Osamah; Corman, Victor M.; Drosten, Christian; Schaade, Lars; Wieler, Lothar H.; CoMoLo Study Group; Lampert, ThomasAfter a large church concert on 1 March 2020 and a first detected infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on 9 March, the southern German community of Kupferzell in the federal state ...
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2020-12-02ZeitschriftenartikelSevere Acute Respiratory Syndrome Coronavirus 2 Outbreak Related to a Nightclub, Germany, 2020 Muller, Nadine; Kunze, Mareike; Steitz, Fabienne; Saad, Neil J.; Mühlemann, Barbara; Beheim-Schwarzbach, Jörn I.; Schneider, Julia; Drosten, Christian; Murajda, Lukas; Kochs, Sandra; Ruscher, Claudia; Walter, Jan; Zeitlmann, Nadine; Corman, Victor M.We report an outbreak of coronavirus disease with 74 cases related to a nightclub in Germany in March 2020. Staff members were particularly affected (attack rate 56%) and likely caused sustained viral transmission after ...