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Auflistung nach Autor "Nitsche, Andreas"
Anzeige der Publikationen 1-20 von 130
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2019-01-11ZeitschriftenartikelA cross-sectional screening by next-generation sequencing reveals Rickettsia, Coxiella, Francisella, Borrelia, Babesia, Theileria and Hemolivia species in ticks from Anatolia Brinkmann, Annika; Hekimoğlu, Olcay; Dinçer, Ender; Hagedorn, Peter; Nitsche, Andreas; Ergünay, KorayBackground Ticks participate as arthropod vectors in the transmission of pathogenic microorganisms to humans. Several tick-borne infections have reemerged, along with newly described agents of unexplored pathogenicity. ...
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2017-09-29ZeitschriftenartikelA Cross-Sectional Serosurvey of Anti-Orthopoxvirus Antibodies in Central and Western Africa Leendertz, Siv Aina J.; Stern, Daniel; Theophil, Dennis; Anoh, Etile; Mossoun, Arsène; Schubert, Grit; Wiersma, Lidewij; Akoua-Koffi, Chantal; Couacy-Hymann, Emmanuel; Muyembe-Tamfum, Jean-Jacques; Karhemere, Stomy; Pauly, Maude; Schrick, Livia; Leendertz, Fabian H.; Nitsche, AndreasSince the eradication of smallpox and the subsequent discontinuation of the worldwide smallpox vaccination program, other Orthopoxviruses beside Variola virus have been increasingly representing a risk to human health. To ...
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2017-10-13ZeitschriftenartikelA Next-Generation Sequencing Approach Uncovers Viral Transcripts Incorporated in Poxvirus Virions Grossegesse, Marica; Döllinger, Jörg; Haldemann, Berit; Schaade, Lars; Nitsche, AndreasTranscripts are known to be incorporated in particles of DNA viruses belonging to the families of Herpesviridae and Mimiviridae, but the presence of transcripts in other DNA viruses, such as poxviruses, has not been analyzed ...
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2010-04-29ZeitschriftenartikelA Novel Highly Reproducible and Lethal Nonhuman Primate Model for Orthopox Virus Infection Kramski, Marit; Mätz-Rensing, Kerstin; Stahl-Hennig, Christiane; Kaup, Franz-Josef; Nitsche, Andreas; Pauli, Georg; Ellerbrok, HeinzThe intentional re-introduction of Variola virus (VARV), the agent of smallpox, into the human population is of great concern due its bio-terroristic potential. Moreover, zoonotic infections with Cowpox (CPXV) and Monkeypox ...
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2020-09-23ZeitschriftenartikelAbwägung der Dauer von Quarantäne und Isolierung bei COVID-19 von Kleist, Max; Ruehe, Bettina; Oh, Dschin-Je; Nitsche, Andreas; Haas, Walter; Stoliaroff-Pépin, Anna; Eckmanns, Tim; Abu Sin, Muna; van der Toorn, Wiep; Jenny, Mirjam; Mielke, Martin; Herzog, Christian; Wieler, Lothar H.Abwägung der Dauer von Quarantäne und Isolierung bei COVID-19 Angesichts weltweit zunehmender Fallzahlen mit SARS-CoV-2 ist die konsequente Einhaltung von Maßnahmen zur Verlangsamung der Ausbreitung erforderlich. Grundlage ...
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2021-03-24ZeitschriftenartikelAmantadine Inhibits SARS-CoV-2 In Vitro FInk, Klaus; Nitsche, Andreas; Neumann, Markus; Grossegesse, Marica; Eisele, Karl-Heinz; Danysz, WojciechSince the SARS-CoV-2 pandemic started in late 2019, the search for protective vaccines and for drug treatments has become mandatory to fight the global health emergency. Travel restrictions,social distancing, and face masks ...
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2021-07-01ZeitschriftenartikelAmpliCoV: Rapid Whole-Genome Sequencing Using Multiplex PCR Amplification and Real-Time Oxford Nanopore MinION Sequencing Enables Rapid Variant Identification of SARS-CoV-2 Brinkmann, Annika; Ulm, Sophie-Luisa; Uddin, Steven; Förster, Sophie; Seifert, Dominique; Oehme, Rainer; Corty, Merle; Schaade, Lars; Michel, Janine; Nitsche, AndreasSince the emergence of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) in December 2019, the scientific community has been sharing data on epidemiology, diagnostic methods, and whole-genomic sequences ...
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2021-04-20ZeitschriftenartikelAn intra-host SARS-CoV-2 dynamics model to assess testing and quarantine strategies for incoming travelers, contact management, and de-isolation van der Toorn, Wiep; Oh, Djin-Ye; Bourquain, Daniel; Michel, Janine; Krause, Eva; Nitsche, Andreas; von Kleist, MaxNon-pharmaceutical interventions (NPIs) remain decisive tools to contain SARS-CoV-2. Strategies that combine NPIs with testing may improve efficacy and shorten quarantine durations. We developed a stochastic within-host ...
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2011-01-03ZeitschriftenartikelAnionic Polysaccharides From Phototrophic Microorganisms Exhibit Antiviral Activities to Vaccinia Virus Radonić, Aleksandar; Thulke, Stefanie; Achenbach, John; Kurth, Andreas; Vreemann, Anna; König, Tanja; Walter, Christian; Possinger, Kurt; Nitsche, AndreasThe aim of the present study was to characterise anti-vaccinia virus activities of anionic exopolysaccharides TK V3 isolated from cyanobacterium Arthrospira platensis and an exopolysaccharide isolated from the rhodophyt ...
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2021-02-22ZeitschriftenartikelApplication of spectral library prediction for parallel reaction monitoring of viral peptides Grossegesse, Marica; Nitsche, Andreas; Schaade, Lars; Döllinger, JörgA major part of the analysis of parallel reaction monitoring (PRM) data is the comparison of observed fragment ion intensities to a library spectrum. Classically, these libraries are generated by data-dependent acquisition ...
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2019-05-06ZeitschriftenartikelArboviral screening of invasive Aedes species in northeastern Turkey: West Nile virus circulation and detection of insect-only viruses Akıner, Mustafa M.; Öztürk, Murat; Buğra Başer, Aykut; Günay, Filiz; Hacıoğlu, Sabri; Brinkmann, Annika; Emanet, Nergis; Alten, Bülent; Özkul, Aykut; Nitsche, Andreas; Linton, Yvonne-Marie; Ergünay, KorayBackground The recent reports of Aedes aegypti and Ae. albopictus populations in Turkey, in parallel with the territorial expansion identified in several surrounding countries, have raised concerns about the establishment ...
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2012-12-06ZeitschriftenartikelAssays for laboratory confirmation of novel human coronavirus (hCoV-EMC) infections Corman, V. M.; Müller, Marcel A.; Costabel, U.; Timm, J.; Binger, T.; Meyer, B.; Kreher, Petra; Lattwein, Erik; Eschbach-Bludau, M.; Nitsche, Andreas; Bleicker, T.; Landt, Olfert; Schweiger, Brunhilde; Drexler, Jan Felix; Osterhaus, A. D.; Haagmans, B. L.; Dittmer, U.; Bonin, F.; Wolff, Thorsten; Drosten, ChristianWe present a rigorously validated and highly sensitive confirmatory real-time RT-PCR assay (1A assay) that can be used in combination with the previously reported upE assay. Two additional RT-PCR assays for sequencing are ...
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2017-10-01ZeitschriftenartikelBerlin Squirrelpox Virus, a New Poxvirus in Red Squirrels, Berlin, Germany Wibbelt, Gudrun; Tausch, Simon H.; Dabrowski, Piotr Wojtek; Kershaw, Olivia; Nitsche, Andreas; Schrick, LiviaNear Berlin, Germany, several juvenile red squirrels (Sciurus vulgaris) were found with moist, crusty skin lesions. Histology, electron microscopy, and cell culture isolation revealed an orthopoxvirus-like infection. ...
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2018-07-26ZeitschriftenartikelBeyond the myths: Novel findings for old paradigms in the history of the smallpox vaccine Esparza, José; Nitsche, Andreas; Damaso, Clarissa R.The discovery of smallpox vaccination by Edward Jenner in 1796 gave a new perspective to science in the struggle against this devastating disease. Smallpox has claimed hundreds of millions of lives over the centuries. ...
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2017-03-20ZeitschriftenartikelCo-circulation of West Nile virus and distinct insect-specific flaviviruses in Turkey Ergünay, Koray; Litzba, Nadine; Brinkmann, Annika; Günay, Filiz; Sarıkaya, Yasemen; Kar, Sırrı; Örsten, Serra; Öter, Kerem; Domingo, Cristina; Kasap, Özge Erisoz; Özkul, Aykut; Mitchell, Luke; Nitsche, Andreas; Alten, Bülent; Linton, Yvonne-MarieBackground: Active vector surveillance provides an efficient tool for monitoring the presence or spread of emerging or re-emerging vector-borne viruses. This study was undertaken to investigate the circulation of ...
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2017-11-10ZeitschriftenartikelCombined Proteomics/Genomics Approach Reveals Proteomic Changes of Mature Virions as a Novel Poxvirus Adaptation Mechanism Grossegesse, Marica; Döllinger, Jörg; Tyshaieva, Alona; Schaade, Lars; Nitsche, AndreasDNA viruses, like poxviruses, possess a highly stable genome, suggesting that adaptation of virus particles to specific cell types is not restricted to genomic changes. Cowpox viruses are zoonotic poxviruses with an ...
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2015-04-02ZeitschriftenartikelComparative Genomic Analysis of Two Novel Sporadic Shiga Toxin-Producing Escherichia coli O104:H4 Strains Isolated 2011 in Germany Tietze, Erhard; Dabrowski, Piotr Wojtek; Prager, Rita; Radonić, Aleksandar; Fruth, Angelika; Aurass, Philipp; Nitsche, Andreas; Mielke, Martin; Flieger, AntjeA large outbreak of gastrointestinal disease occurred in 2011 in Germany which resulted in almost 4000 patients with acute gastroenteritis or hemorrhagic colitis, 855 cases of a hemolytic uremic syndrome and 53 deaths. The ...
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2021-06-15ZeitschriftenartikelComparative Pathogenesis, Genomics and Phylogeography of Mousepox Mavian, Carla; López-Bueno, Alberto; Martín, Rocío; Nitsche, Andreas; Alcamí, AntonioEctromelia virus (ECTV), the causative agent of mousepox, has threatened laboratory mouse colonies worldwide for almost a century. Mousepox has been valuable for the understanding of poxvirus pathogenesis and immune ...
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2015-10-15ZeitschriftenartikelComparison of 454 Ultra-Deep Sequencing and Allele-Specific Real-Time PCR with Regard to the Detection of Emerging Drug-Resistant Minor HIV-1 Variants after Antiretroviral Prophylaxis for Vertical Transmission Hauser, Andrea; Kücherer, Claudia; Kunz, Andrea; Dabrowski, Piotr Wojtek; Radonić, Aleksandar; Nitsche, Andreas; Theuring, Stefanie; Bannert, Norbert; Sewangi, Julius; Mbezi, Paulina; Dugange, Festo; Harms, Gundel; Meixenberger, KarolinBackground: Pregnant HIV-infected women were screened for the development of HIV-1 drug resistance after implementation of a triple-antiretroviral transmission prophylaxis as recommended by the WHO in 2006. The study ...
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2013-02-20ZeitschriftenartikelComparison of host cell gene expression in cowpox, monkeypox or vaccinia virus-infected cells reveals virus-specific regulation of immune response genes Bourquain, Daniel; Dabrowski, Piotr Wojtek; Nitsche, AndreasBackground: Animal-borne orthopoxviruses, like monkeypox, vaccinia and the closely related cowpox virus, are all capable of causing zoonotic infections in humans, representing a potential threat to human health. The ...