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Auflistung nach Autor "Piesker, Janett"
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2018-05-02ZeitschriftenartikelA lipid-binding loop of botulinum neurotoxin serotypes B, DC and G is an essential feature to confer their exquisite potency Stern, Daniel; Weisemann, Jasmin; Le Blanc, Alexander; von Berg, Laura; Mahrhold, Stefan; Piesker, Janett; Laue, Michael; Luppa, Peter B.; Dorner, Martin B.; Dorner, Brigitte G.; Rummel, AndreasThe exceptional toxicity of botulinum neurotoxins (BoNTs) is mediated by high avidity binding to complex polysialogangliosides and intraluminal segments of synaptic vesicle proteins embedded in the presynaptic membrane. ...
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2016-03-01ZeitschriftenartikelDevelopment of a Genus-Specific Antigen Capture ELISA for Orthopoxviruses – Target Selection and Optimized Screening Stern, Daniel; Pauly, Diana; Zydek, Martin; Miller, Lilija; Piesker, Janett; Laue, Michael; Lisdat, Fred; Dorner, Martin; Dorner, Brigitte; Nitsche, AndreasOrthopoxvirus species like cowpox, vaccinia and monkeypox virus cause zoonotic infections in humans worldwide. Infections often occur in rural areas lacking proper diagnostic infrastructure as exemplified by monkeypox, ...
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2013-07-12ZeitschriftenartikelDNA Uptake by the Nosocomial Pathogen Acinetobacter baumannii Occurs during Movement along Wet Surfaces Wilharm, Gottfried; Piesker, Janett; Laue, Michael; Skiebe, EvelynThe emergence of Acinetobacter baumannii as an increasingly multidrug-resistant nosocomial pathogen largely relies on acquisition of resistance genes via horizontal gene transfer. Here, we demonstrate that many clinical ...
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2018-01-29ZeitschriftenartikelGlobal ubiquitination analysis reveals extensive modification and proteasomal degradation of cowpox virus proteins, but preservation of viral cores Grossegesse, Marica; Doellinger, Joerg; Fritsch, Annemarie; Laue, Michael; Piesker, Janett; Schaade, Lars; Nitsche, AndreasThe emergence of Variola virus-like viruses by natural evolution of zoonotic Orthopoxviruses, like Cowpox virus (CPXV), is a global health threat. The proteasome is essential for poxvirus replication, making the viral ...