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Anzeige der Publikationen 88-107 von 11528
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2022-09StudienarbeitA health economic evaluation of prostate-specific antigen-based risk-stratified prostate cancer screening strategies in Germany Prostate cancer (PCa) screening remains a controversial topic. The value of population-based screening in reducing premature deaths remains unclear, primarily due to over-diagnosis and overtreatments. However, with an ...
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2017-01-12ZeitschriftenartikelA joint cross-border investigation of a cluster of multidrug-resistant tuberculosis in Austria, Romania and Germany in 2014 using classic, genotyping and whole genome sequencing methods: lessons learnt Molecular surveillance of multidrug-resistant tuberculosis (MDR-TB) using 24-loci MIRU-VNTR in the European Union suggests the occurrence of international transmission. In early 2014, Austria detected a molecular MDR-TB ...
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2020-12-09ZeitschriftenartikelA Klebsiella pneumoniae ST307 outbreak clone from Germany demonstrates features of extensive drug resistance, hypermucoviscosity, and enhanced iron acquisition Background Antibiotic-resistant Klebsiella pneumoniae are a major cause of hospital- and community-acquired infections, including sepsis, liver abscess, and pneumonia, driven mainly by the emergence of successful high-risk ...
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2017-10-31ZeitschriftenartikelA large proportion of people who inject drugs are susceptible to hepatitis B: Results from a bio-behavioural study in eight German cities Background: People who inject drugs (PWID) are at high risk of hepatitis B virus (HBV) infection by sharing needles and drug use paraphernalia. In Germany, no routine surveillance of HBV prevalence and vaccination ...
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2018-05-02ZeitschriftenartikelA lipid-binding loop of botulinum neurotoxin serotypes B, DC and G is an essential feature to confer their exquisite potency The exceptional toxicity of botulinum neurotoxins (BoNTs) is mediated by high avidity binding to complex polysialogangliosides and intraluminal segments of synaptic vesicle proteins embedded in the presynaptic membrane. ...
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2019-01-16ZeitschriftenartikelA Listeria monocytogenes ST2 clone lacking chitinase ChiB from an outbreak of non-invasive gastroenteritis An outbreak with a remarkable Listeria monocytogenes clone causing 163 cases of non-invasive listeriosis occurred in Germany in 2015. Core genome multi locus sequence typing grouped non-invasive outbreak isolates and ...
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2010-03-23ZeitschriftenartikelA longitudinal study of urinary dipstick parameters in wild chimpanzees (Pan troglodytes verus) in Côte d'ivoire We performed 796 dip-stick tests on urine from 100 wild West African chimpanzees (Pan troglodytes verus) from 4 habituated groups in the tropical rain forest of Taï National Park, Cote d'Ivoire, to establish reference ...
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2016-01-22ZeitschriftenartikelA Look into the Melting Pot: The mecC-Harboring Region Is a Recombination Hot Spot in Staphylococcus stepanovicii Introduction: Horizontal gene transfer (HGT) is an important driver for resistance- and virulence factor accumulation in pathogenic bacteria such as Staphylococcus aureus. Methods: Here, we have investigated the ...
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2013-07-16ZeitschriftenartikelA Mouse Model for Human Norovirus Human noroviruses (HuNoVs) cause significant morbidity and mortality worldwide. However, despite substantial efforts, a small-animal model for HuNoV has not been described to date. Since "humanized" mice have been successfully ...
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2014-08-07ZeitschriftenartikelA multi-country outbreak of Salmonella Newport gastroenteritis in Europe associated with watermelon from Brazil, confirmed by whole genome sequencing: October 2011 to January 2012 In November 2011, the presence of Salmonella Newport in a ready-to-eat watermelon slice was confirmed as part of a local food survey in England. In late December 2011, cases of S. Newport were reported in England, Wales, ...
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2020-11-28ZeitschriftenartikelA Multi-Omics Protocol for Swine Feces to Elucidate Longitudinal Dynamics in Microbiome Structure and Function Swine are regarded as promising biomedical models, but the dynamics of their gastrointestinal microbiome have been much less investigated than that of humans or mice. The aim of this study was to establish an integrated ...
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2023-05-11ZeitschriftenartikelA multicentre external quality assessment: A first step to standardise PCR protocols for the diagnosis of histoplasmosis and coccidioidomycosis Background In-house real-time PCR (qPCR) is increasingly used to diagnose the so-called endemic mycoses as commercial assays are not widely available. Objectives To compare the performance of different molecular ...
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2014-08-14ZeitschriftenartikelA multicentre sero-behavioural survey for hepatitis B and C, HIV and HTLV among people who inject drugs in Germany using respondent driven sampling Background: People who inject drugs are at high risk for hepatitis B, hepatitis C and HIV. HTLV was reported by neighboring countries to be prevalent in this population, but the situation for Germany is unclear. To ...
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2006-01-27ZeitschriftenartikelA New Bacillus anthracis Found in Wild Chimpanzees and a Gorilla from West and Central Africa
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2018-10-23ZeitschriftenartikelA new hepatitis E virus genotype 2 strain identified from an outbreak in Nigeria, 2017 Background: In 2017 the Nigerian Ministry of Health notified the World Health Organization (WHO) of an outbreak of hepatitis E located in the north-east region of the country with 146 cases with 2 deaths. The analysis ...
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2023-05-16ZeitschriftenartikelA new precedent in international health cooperation from African public health leaders
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2023-05-16Berichte und sonstige TexteA new precedent in international health cooperation from African public health leaders
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2017-10-13ZeitschriftenartikelA Next-Generation Sequencing Approach Uncovers Viral Transcripts Incorporated in Poxvirus Virions Transcripts are known to be incorporated in particles of DNA viruses belonging to the families of Herpesviridae and Mimiviridae, but the presence of transcripts in other DNA viruses, such as poxviruses, has not been analyzed ...
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2010-11-05ZeitschriftenartikelA novel adenovirus of Western lowland gorillas (Gorilla gorilla gorilla) Adenoviruses (AdV) broadly infect vertebrate hosts including a variety of primates. We identified a novel AdV in the feces of captive gorillas by isolation in cell culture, electron microscopy and PCR. From the supernatants ...
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2017-09-18ZeitschriftenartikelA novel Coltivirus-related virus isolated from free-tailed bats from Côte d’Ivoire is able to infect human cells in vitro Background: Zoonotic transmission events play a major role in the emergence of novel diseases. While such events are virtually impossible to predict, wildlife screening for potential emerging pathogens can be a first ...