Browsing by Title
Now showing items 4360-4379 of 10423
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2016-04-21ZeitschriftenartikelI-MOVE multicentre case–control study 2010/11 to 2014/15: Is there within-season waning of influenza type/subtype vaccine effectiveness with increasing time since vaccination? Since the 2008/9 influenza season, the I-MOVE multicentre case–control study measures influenza vaccine effectiveness (VE) against medically-attended influenza-like-illness (ILI) laboratory confirmed as influenza. In ...
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2021-07-29ZeitschriftenartikelICD-10-Code-basierte syndromische Surveillance akuter Atemwegserkrankungen mit COVID-19 im ambulanten Bereich In Deutschland erfolgt die syndromische Surveillance akuter respiratorischer Erkrankungen (ARE) im ambulanten Bereich durch die Arbeitsgemeinschaft Influenza des RKI. Seit 2006 existiert neben den klassischen Meldewegen ...
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2019-11-22ZeitschriftenartikelICD-Codierung von Todesursachen: Herausforderungen bei der Berechnung der Krankheitslast in Deutschland Im Projekt BURDEN 2020 – Die Krankheitslast in Deutschland und seinen Regionen – werden anhand der amtlichen Todesursachenstatistik die durch vorzeitige Sterblichkeit verlorenen Lebensjahre (Years of Life Lost, YLL) ...
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2019-01-23DissertationIdentification and Analysis of Cleavage Sites and Subdomains in the Group Specific Antigen (Gag) of the Human Endogenous Retrovirus-K(HML-2) Interestingly at molecular level humans and chimpanzees are very similar. The average DNA sequence difference between them is ~4% (Varki and Altheide, 2009). Contributing to the difference in humans are human endogenous ...
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2013-05-03DissertationIdentification and characterisation of emerging viruses in free-ranging bats from sub-Saharan Africa Neuartige zoonotische Krankheitserreger stellen eine wachsende Bedrohung für den Menschen dar und sind eine der größten Herausforderungen des modernen globalen Gesundheitsmanagements. Tropische Regionen bergen aufgrund der ...
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2016-10-20ZeitschriftenartikelIdentification and Characterization of VNI/VNII and Novel VNII/VNIV Hybrids and Impact of Hybridization on Virulence and Antifungal Susceptibility Within the C. neoformans/C. gattii Species Complex Cryptococcus neoformans and C. gattii are pathogenic basidiomycetous yeasts and the commonest cause of fungal infection of the central nervous system. Cryptococci are typically haploid but several inter-species, inter-varietal ...
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2009-12-21ZeitschriftenartikelIdentification of a novel betaherpesvirus in Mus musculus Rodent betaherpesviruses vary considerably in genomic content, and these variations can result in a distinct pathogenicity. Therefore, the identification of unknown betaherpesviruses in house mice (Mus musculus), the ...
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2017-05-18ZeitschriftenartikelIdentification of a Novel Hepatitis E Virus Genotype 3 Strain Isolated from a Chronic Hepatitis E Virus Infection in a Kidney Transplant Recipient in Switzerland Hepatitis E virus genotype 3 (HEV-3) is the causal pathogen of chronic hepatitis E. We report here the full-length genome sequence of an HEV-3 strain, isolated from a kidney transplant recipient in Switzerland (SW/16-0282). ...
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2013-03-13ZeitschriftenartikelIdentification of a Novel Human Polyomavirus in Organs of the Gastrointestinal Tract Polyomaviruses are small, non-enveloped viruses with a circular double-stranded DNA genome. Using a generic polyomavirus PCR targeting the VP1 major structural protein gene, a novel polyomavirus was initially identified ...
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2021-04-26ZeitschriftenartikelIdentification of a Putative Novel Genotype of Avian Hepatitis E Virus from Apparently Healthy Chickens in Southwestern Nigeria Avian hepatitis E virus (aHEV) is the major etiological agent of hepatitis-splenomegaly syndrome (HSS), big liver and spleen disease (BLSD), and hepatic rupture hemorrhage syndrome (HRHS) in chickens. Infections with aHEV ...
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2016-10-06ZeitschriftenartikelIdentification of Differentially Expressed Genes during Bacillus subtilis Spore Outgrowth in High-Salinity Environments Using RNA Sequencing In its natural habitat, the soil bacterium Bacillus subtilis often has to cope with fluctuating osmolality and nutrient availability. Upon nutrient depletion it can form dormant spores, which can revive to form vegetative ...
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2013-11-19ZeitschriftenartikelIdentification of late assembly domains of the human endogenous retrovirus-K(HML-2) Background: Late assembly (L)-domains are protein interaction motifs, whose dysfunction causes characteristic budding defects in enveloped viruses. Three different amino acid motifs, namely PT/SAP, PPXY and YPXnL have ...
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2022-03-11ZeitschriftenartikelIdentification of Mucormycosis by Fluorescence In Situ Hybridization Targeting Ribosomal RNA in Tissue Samples Mucormycosis is an invasive fungal infection associated with high mortality, partly due to delayed diagnosis and inadequate empiric therapy. As fungal cultures often fail to grow Mucorales, identification of respective ...
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2021-11-13ZeitschriftenartikelIdentification of Oocyst-Driven Toxoplasma gondii Infections in Humans and Animals through Stage-Specific Serology—Current Status and Future Perspectives The apicomplexan zoonotic parasite Toxoplasma gondii has three infective stages: sporozoites in sporulated oocysts, which are shed in unsporulated form into the environment by infected felids; tissue cysts containing ...
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2017-08-17ZeitschriftenartikelIdentification of Polo-like kinases as potential novel drug targets for influenza A virus In recent years genome-wide RNAi screens have revealed hundreds of cellular factors required for influenza virus infections in human cells. The long-term goal is to establish some of them as drug targets for the development ...
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2013-07-24ZeitschriftenartikelIdentification of the feline foamy virus Bet domain essential for APOBEC3 counteraction Background: APOBEC3 (A3) proteins restrict viral replication by cytidine deamination of viral DNA genomes and impairing reverse transcription and integration. To escape this restriction, lentiviruses have evolved the ...
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2011-05-09ZeitschriftenartikelIdentification of the protease cleavage sites in a reconstituted Gag polyprotein of an HERV-K(HML-2) element Background: The human genome harbors several largely preserved HERV-K(HML-2) elements. Although this retroviral family comes closest of all known HERVs to producing replication competent virions, mutations acquired during ...
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2013-09-30ZeitschriftenartikelIdentifizierung von Pilzen in Gewebeschnitten mit Fluoreszenz-in-situ-Hybridisierung Pilzinfektionen sind trotz der Verfügbarkeit neuer Antimykotika mit einer hohen Letalität assoziiert. Aufgrund differenter Empfindlichkeit verschiedener Pilze kommt der Erregeridentifizierung eine entscheidende Bedeutung ...
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2022-04-11ZeitschriftenartikelIdentifying content to improve risk assessment communications within the Risk Profile: Literature reviews and focus groups with expert and non-expert stakeholders Objective: To improve consumer decision making, the results of risk assessments on food, feed, consumer products or chemicals need to be communicated not only to experts but also to non-expert audiences. The present study ...
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2006-10-24ZeitschriftenartikelIdentifying outbreaks of sexually transmitted infection: who cares? Background: Current routine surveillance schemes for sexually transmitted infections (STIs) in the United Kingdom (UK) are not designed for outbreak identification. Recognising STI outbreaks, therefore, depends almost ...