Browsing by Subject "Base Sequence"
Now showing items 1-20 of 22
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2008-05-08ZeitschriftenartikelA European laboratory network for sequence-based typing of methicillin-resistant Staphylococcus aureus (MRSA) as a communication platform between human and veterinary medicine – an update on SeqNet.org
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2009-11-09ZeitschriftenartikelA novel herpesvirus in the sanctuary chimpanzees on Ngamba Island in Uganda Background: Recent studies in non-human primates have led to the discovery of novel primate herpesviruses. In order to get more information on herpesvirus infections in apes, we studied wild born captive chimpanzees. ...
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2002-07-31ZeitschriftenartikelAssociation of two newly recognized herpesviruses with interstitial pneumonia in donkeys (Equus asinus) Over a period of 6 years, antemortem and postmortem examinations were performed on a number of donkeys suffering from respiratory disease. For many cases, initial diagnostic efforts failed to identify an etiology consistent ...
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2012-12-26ZeitschriftenartikelBiological and Phylogenetic Characteristics of Yellow Fever Virus Lineages from West Africa The yellow fever virus (YFV), the first proven human-pathogenic virus, although isolated in 1927, is still a major public health problem, especially in West Africa where it causes outbreaks every year. Nevertheless, little ...
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2010-04-01ZeitschriftenartikelCharacterisation of a human cell-adapted porcine endogenous retrovirus PERV-A/C. Background: Porcine endogenous retroviruses (PERVs) pose a potential risk for xenotransplantation using pig cells, tissues or organs. A special threat comes from viruses generated by recombination between human-tropic ...
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2015-06-16ZeitschriftenartikelCross talk between the response regulators PhoB and TctD allows for the integration of diverse environmental signals in Pseudomonas aeruginosa Two-component systems (TCS) serve as stimulus-response coupling mechanisms to allow organisms to adapt to a variety of environmental conditions. The opportunistic pathogen Pseudomonas aeruginosa encodes for more than 100 ...
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2013-10-23ZeitschriftenartikelCytomegalovirus expresses the chemokine homologue vXCL1 capable of attracting XCR1+CD4- dendritic cells Cytomegaloviruses (CMV) have developed various strategies to escape the immune system of the host. One strategy involves the expression of virus-encoded chemokines to modulate the host chemokine network. We have identified ...
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2011-12-28ZeitschriftenartikelDiseases and causes of death in European bats: dynamics in disease susceptibility and infection rates. Background: Bats receive increasing attention in infectious disease studies, because of their well recognized status as reservoir species for various infectious agents. This is even more important, as bats with their ...
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2009-11-01ZeitschriftenartikelEpidemiology of Hepatitis A Virus Infections, 2007-2008 Approximately 60% of hepatitis A virus infections in Germany occur in persons without a travel history to disease-endemic areas and for whom sources of infection are unknown. Recommendation of pretravel vaccination fails ...
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2012-08-05ZeitschriftenartikelFliA expression analysis and influence of the regulatory proteins RpoN, FleQ and FliA on virulence and in vivo fitness in Legionella pneumophila In Legionella pneumophila, the regulation of the flagellum and the expression of virulence traits are linked. FleQ, RpoN and FliA are the major regulators of the flagellar regulon. We demonstrated here that all three ...
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2014-12-18ZeitschriftenartikelFoodborne hepatitis A outbreak associated with bakery products in northern Germany, 2012 In October 2012, a hepatitis A (HA) outbreak with 83 laboratory-confirmed cases occurred in Lower Saxony. We defined primary outbreak cases as people with laboratory-confirmed HA and symptom onset between 8 October and 12 ...
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2012-03-23ZeitschriftenartikelGenetic Evidence of Functional Ficolin-2 Haplotype as Susceptibility Factor in Cutaneous Leishmaniasis Background: Ficolin-2 coded by FCN2 gene is a soluble serum protein that plays an important role in innate immunity. In this study, we analyzed five functional polymorphisms of the FCN2 gene for their possible association ...
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2012-01-01ZeitschriftenartikelHantavirus in Bat, Sierra Leone
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2010-09-27ZeitschriftenartikelImproved Detection of Mutated Human Cytomegalovirus UL97 by Pyrosequencing Ganciclovir (GCV) resistance frequently occurs upon prolonged treatment of ongoing active human cytomegalovirus (HCMV) infection in individuals with immature or compromised immune functions (e.g., recipients of solid-organ ...
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2015-02-06ZeitschriftenartikelIsolation and Functional Characterization of the Novel Clostridium botulinum Neurotoxin A8 Subtype Botulism is a severe neurological disease caused by the complex family of botulinum neurotoxins (BoNT). Based on the different serotypes known today, a classification of serotype variants termed subtypes has been proposed ...
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2011-09-30ZeitschriftenartikelLife cycle stage-resolved proteomic analysis of the excretome/secretome from Strongyloides ratti - identification of stage-specific proteases. A wide range of biomolecules, including proteins, are excreted and secreted from helminths and contribute to the parasite's successful establishment, survival, and reproduction in an adverse habitat. Excretory and secretory ...
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2012-06-13ZeitschriftenartikelMycobacterium tuberculosis DosR Regulon Gene Rv0079 Encodes a Putative, ‘Dormancy Associated Translation Inhibitor (DATIN)’ Mycobacterium tuberculosis is a major human pathogen that has evolved survival mechanisms to persist in an immune-competent host under a dormant condition. The regulation of M. tuberculosis metabolism during latent infection ...
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2009-06-24ZeitschriftenartikelNovel cytomegaloviruses in free-ranging and captive great apes: phylogenetic evidence for bidirectional horizontal transmission Wild great apes often suffer from diseases of unknown aetiology. This is among the causes of population declines. Because human cytomegalovirus (HCMV) is an important pathogen, especially in immunocompromised individuals, ...
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2015-08-07ZeitschriftenartikelPhenotypic and Genotypic Characteristics of Members of the Genus Streptobacillus The genus Streptobacillus (S.) remained monotypic for almost 90 years until two new species were recently described. The type species, S. moniliformis, is one of the two etiological agents of rat bite fever, an under-diagnosed, ...
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2008-11-19ZeitschriftenartikelSpecific Inhibition of the PKR-Mediated Antiviral Response by the Murine Cytomegalovirus Proteins m142 and m143 Double-stranded RNA (dsRNA) produced during viral infection activates several cellular antiviral responses. Among the best characterized is the shutoff of protein synthesis mediated by the dsRNA-dependent protein kinase ...