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Now showing items 10512-10531 of 11527
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2018-09-10ZeitschriftenartikelThe significance of human respiratory syncytial virus (HRSV) in children from Ghana with acute lower respiratory tract infection: A molecular epidemiological analysis, 2006 and 2013-2014 Background: Acute lower respiratory tract infection (ALRI) is a leading cause of childhood morbidity and mortality in developing countries. Globally, human respiratory syncytial virus (HRSV) is the most common pathogen ...
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2021-07-22ZeitschriftenartikelThe Similarity-Updating Model of Probability Judgment and Belief Revision People often take nondiagnostic information into account when revising their beliefs. A probability judgment decreases due to nondiagnostic information represents the well-established “dilution effect” observed in many ...
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2021-03-21ZeitschriftenartikelThe Spatiotemporal Dynamics and Microevolution Events That Favored the Success of the Highly Clonal Multidrug-Resistant Monophasic Salmonella Typhimurium Circulating in Europe The European epidemic monophasic variant of Salmonella enterica serovar Typhimurium (S. 1,4,[5],12:i:-) characterized by the multi locus sequence type ST34 and the antimicrobial resistance ASSuT profile has become one of ...
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2019-01-22MasterarbeitThe specific Cell Entry Pathway of the Human Endogenous Retrovirus-K (HML-2) and the Role of Heparan Sulfate Proteoglycans A lot of viruses have been shown to use a wide variety of attachment molecules on cell surfaces and exploit them as receptors and establish an infection (Rostand and Esko, 1997). Viral entry, spread and pathogenesis can ...
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2011-06-30ZeitschriftenartikelThe spread of fecally transmitted parasites in socially-structured populations. Mammals are infected by a wide array of gastrointestinal parasites, including parasites that also infect humans and domesticated animals. Many of these parasites are acquired through contact with infectious stages present ...
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2018-07-03ZeitschriftenartikelThe subjective health of adults in Germany The term ‘subjective health’ reflects not only existing illnesses and health complaints, but particularly emphasizes the personal well-being. Studies often collect data on subjective health by asking participants to provide ...
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2019-02-02ZeitschriftenartikelThe successful uptake and sustainability of rapid infectious disease and antimicrobial resistance point-of-care testing requires a complex ‘mix-and-match’ implementation package The emergence and spread of antimicrobial resistance is one of the major global issues currently threatening the health and wealth of nations, with effective guidelines and intervention strategies urgently required. Such ...
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2006-12-21ZeitschriftenartikelThe transmembrane envelope protein of HIV-1 and other retroviruses modulate cytokine production and induce Treg cells
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2013-08-07ZeitschriftenartikelThe Transmembrane Protein of the Human Endogenous Retrovirus - K (HERV-K) Modulates Cytokine Release and Gene Expression Numerous copies of endogenous retroviruses are present in the genome of mammals including man. Although most of them are defective, some, e.g., the human endogenous retroviruses HERV-K, were found to be expressed under ...
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2014-03-21ZeitschriftenartikelThe type IV secretion protein TraK from the Enterococcus conjugative plasmid pIP501 exhibits a novel fold Conjugative plasmid transfer presents a serious threat to human health as the most important means of spreading antibiotic resistance and virulence genes among bacteria. The required direct cell-cell contact is established ...
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2019-02-11ZeitschriftenartikelThe tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family Apicomplexan parasites are auxotrophic for a range of amino acids which must be salvaged from their host cells, either through direct uptake or degradation of host proteins. Here, we describe a family of plasma membrane-localized ...
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2017-12-13ZeitschriftenartikelThe uptake of influenza vaccination for the 2013/2014 season in Germany Seasonal influenza (flu) is an acute viral disease that occurs every winter in Germany and is referred to as the ‘flu wave’. The Standing Committee on Vaccination (STIKO) at the Robert Koch Institute recommends annual ...
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2018-02-24ZeitschriftenartikelThe use of high-throughput sequencing to investigate an outbreak of glycopeptide-resistant Enterococcus faecium with a novel quinupristin-dalfopristin resistance mechanism High-throughput sequencing (HTS) has successfully identified novel resistance genes in enterococci and determined clonal relatedness in outbreak analysis. We report the use of HTS to investigate two concurrent outbreaks ...
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2018-08-06ZeitschriftenartikelThe usefulness of C-reactive protein in predicting malaria parasitemia in a sub-Saharan African region Background: Malaria remains a leading cause of childhood mortality in sub-Saharan Africa. Identifying patients who are at risk for severe manifestations at presentation still remains challenging. This study examines ...
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2020-02-22ZeitschriftenartikelThe Utility of Human Immune System Mice for High-Containment Viral Hemorrhagic Fever Research Human immune system (HIS) mice are a subset of humanized mice that are generated by xenoengraftment of human immune cells or tissues and/or their progenitors into immunodeficient mice. Viral hemorrhagic fevers (VHFs) cause ...
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2017-12-13ZeitschriftenartikelThe utilization of colonoscopy in Germany Colorectal cancer is one of the three most common cancers in German adults. There are several legally based examinations for the early detection of colorectal cancer. People aged 50 to 54 years can have a faecal blood ...
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2017-12-13ZeitschriftenartikelThe utilization of psychiatric and psychotherapeutic services in Germany – individual determinants and regional differences In Germany, the provision of health services to people with mental disorders is an issue that is subject to controversial debate. On the one hand, regional differences exist in the distribution of psychotherapists in ...
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2021-04-01ZeitschriftenartikelThe virome ofGerman bats: comparing virus discovery approaches Bats are known to be reservoirs of several highly pathogenic viruses. Hence, the interest in bat virus discovery has been increasing rapidly over the last decade. So far, most studies have focused on a single type of virus ...
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2021-06-14ZeitschriftenartikelThe whole is greater than the sum of its parts: profles of multiple mental health risk factors using Latent class analysis Background: The exposure to an accumulation of various risk factors during childhood and adolescence relative to a single risk is associated with poorer mental health. Identifcation of distinct constellations of risk ...
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2007-07-05ZeitschriftenartikelThe Yersinia enterocolitica type three secretion chaperone SycO is integrated into the Yop regulatory network and binds to the Yop secretion protein YscM1 Background: Pathogenic yersiniae (Y. pestis, Y. pseudotuberculosis, Y. enterocolitica) share a virulence plasmid encoding a type three secretion system (T3SS). This T3SS comprises more than 40 constituents. Among these ...