Auflistung nach Titel
Anzeige der Publikationen 1568-1587 von 11520
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2020-04-21ZeitschriftenartikelCritical Role of Zur and SmtB in Zinc Homeostasis of Mycobacterium smegmatis Zinc homeostasis is crucial for bacterial cells, since imbalances affect viability. However, in mycobacteria, knowledge of zinc metabolism is incomplete. Mycobacterium smegmatis (MSMEG) is an environmental, nonpathogenic ...
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2010-01-20ZeitschriftenartikelCRK adaptor protein expression is required for efficient replication of avian influenza A viruses and controls JNK-mediated apoptotic responses The non-structural protein 1 (A/NS1) of influenza A viruses (IAV) harbours several src-homology domain (SH) binding motifs that are required for interaction with cellular proteins. The SH3 binding motif at aa212-217 [PPLPPK] ...
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2015-06-16ZeitschriftenartikelCross talk between the response regulators PhoB and TctD allows for the integration of diverse environmental signals in Pseudomonas aeruginosa Two-component systems (TCS) serve as stimulus-response coupling mechanisms to allow organisms to adapt to a variety of environmental conditions. The opportunistic pathogen Pseudomonas aeruginosa encodes for more than 100 ...
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2015-02-27ZeitschriftenartikelCross-border comparison of the Dutch and German guidelines on multidrug-resistant Gram-negative microorganisms Background: In all European countries, hospital-acquired infections caused by Gram-negative multidrug-resistant microorganisms (GN-MDRO) are a major health threat, as these pathogens cannot be adequately treated anymore, ...
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2015-10-02ZeitschriftenartikelCross-border outbreak of Salmonella enterica ssp. enterica serovar Bovismorbificans: multiple approaches for an outbreak investigation in Germany and Switzerland QUESTION UNDER STUDY: In July 2014, an outbreak of Salmonella enterica ssp. enterica serovar Bovismorbificans was detected in Switzerland. The goal of the outbreak investigation was to rapidly identify and eliminate the ...
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2020-05-21ZeitschriftenartikelCross-border spread of blaN DM-1- and blaOX A-48 positive Klebsiella pneumoniae: a European collabo-rative analysis of whole genome sequencing and epidemiological data, 2014 to 2019 Analysis of sequencing data for 143 blaNDM-1- and blaOXA-48-positive Klebsiella pneumoniae isolates from 13 European national collections and the public domain resulted in the identification of 15 previously undetected ...
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2019-03-29ZeitschriftenartikelCross-Protective Potential and Protection-Relevant Immune Mechanisms of Whole Inactivated Influenza Virus Vaccines Are Determined by Adjuvants and Route of Immunization Adjuvanted whole inactivated virus (WIV) influenza vaccines show promise as broadly protective influenza vaccine candidates. Using WIV as basis we assessed the relative efficacy of different adjuvants by carrying out a ...
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2009-02-25ZeitschriftenartikelCross-talk between type three secretion system and metabolism in Yersinia. Pathogenic yersiniae utilize a type three secretion system (T3SS) to inject Yop proteins into host cells in order to undermine their immune response. YscM1 and YscM2 proteins have been reported to be functionally equivalent ...
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2012-03-26ZeitschriftenartikelCross-transmission rates of enterococcal isolates among newborns in a neonatal intensive care unit Enterococci are important pathogens causing nosocomial infections and patients at risk include also premature babies requiring intensive care treatment. Our aim was to assess occurrence and cross transmission rates of ...
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2013-10-09ZeitschriftenartikelCryo FIB-SEM: Volume imaging of cellular ultrastructure in native frozen specimens Volume microscopy at high resolution is increasingly required to better understand cellular functions in the context of three-dimensional assemblies. Focused ion beam (FIB) milling for serial block face imaging in the ...
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2021-01-15ZeitschriftenartikelCryptococcus bacillisporus (VGIII) Meningoencephalitis Acquired in Santa Cruz, Bolivia We describe a case of chronic meningoencephalitis with hydrocephalus caused by Crypto- coccus bacillisporus (VGIII) in an immunocompetent patient from Santa Cruz, Bolivia. This first report of a member of the Cryptococcus ...
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2023-01-18ZeitschriftenartikelCrystal structures of OrfX1, OrfX2 and the OrfX1–OrfX3 complex from the orfX gene cluster of botulinum neurotoxin E1 Botulinum neurotoxins (BoNTs) are among the most lethal toxins known to humans, comprising seven established serotypes termed BoNT/A–G encoded in two types of gene clusters (ha and orfX) in BoNT-producing clostridia. The ...
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2009-08-22ZeitschriftenartikelCrystallization and preliminary X-ray diffraction data of an LNA 7-mer duplex derived from a ricin aptamer Locked nucleic acids (LNAs) are modified nucleic acids which contain a modified sugar such as beta-D-2'-O,4'-C methylene-bridged ribofuranose or other sugar derivatives in LNA analogues. The beta-D-2'-O,4'-C methylene ...
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2017-08-18ZeitschriftenartikelCultivable bacterial microbiota from choanae of free-living birds captured in Slovenia We have analysed the structure of cultivable choanal microbiota from free-living birds in relation to bird diet, its richness and the relative number of opportunistic bacteria acquired from the environment. For this purpose, ...
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2009-07-01ZeitschriftenartikelCumulative HIV Viremia during Highly Active Antiretroviral Therapy Is a Strong Predictorof AIDS‐Related Lymphoma Background.AIDS‐related lymphoma contributes to significant morbidity and mortality among human immunodeficiency virus (HIV)–infected patients receiving highly active antiretroviral therapy (HAART). We assessed the predictive ...
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2015-04-10ZeitschriftenartikelCurrent major depressive syndrome measured with the Patient Health Questionnaire-9 (PHQ-9) and the Composite International Diagnostic Interview (CIDI): results from a cross-sectional population-based study of adults in Germany Background: Prevalence estimates for depression vary considerably by the type of assessment instrument, and there is limited information on their overlap in population-based samples. Our aim was to compare the Patient ...
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2015-04-01ZeitschriftenartikelCurrent practices in immunisation policymaking in European countries ECDC TECHNICAL REPORTThis report describes and summarises the national processes for vaccine policymaking currently implemented in EU/EEA countries, the roles of the so-called national technical advisory groups (NITAGs) in the Member States ...
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2015-07-02ZeitschriftenartikelCurrent prevalence of multidrug-resistant organisms in long-term care facilities in the Rhine-Main district, Germany, 2013 Multidrug-resistant organisms (MDRO) and in particular multidrug-resistant Gram-negative organisms (MRGN) are an increasing problem in hospital care. However, data on the current prevalence of MDRO in long-term care ...
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2016-02-11Berichte und sonstige TexteCurrent status of allergy prevalence in Germany The lifetime prevalence of allergic diseases in adults in Germany [self-reported doctor diagnosed allergic diseases, Study on Adult Health in Germany (Studie zur Gesundheit Erwachsener in Deutschland, DEGS1, 2008–2011) of ...
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2012-03-01ZeitschriftenartikelCurrent Trends of Emergence and Spread of Vancomycin-Resistant Enterococci