Auflistung nach Titel
Anzeige der Publikationen 3836-3855 von 11433
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2012-02-16ZeitschriftenartikelExperiences from the Shiga toxin-producing Escherichia coli O104:H4 outbreak in Germany and research needs in the field, Berlin, 28–29 November 2011 This report presents the main findings from an international workshop on Shiga toxin-producing Escherichia coli (STEC), held on 28–29 November 2011, organised by the Robert Koch Institute [1]. The workshop assembled ...
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2020-09-06ZeitschriftenartikelExperiencing the risk of overutilising opioids among patients with chronic non-cancer pain in ambulatory care (ERONA): the protocol of an exploratory, randomised controlled trial Introduction The US opioid crisis and increasing prescription rates in Europe suggest inappropriate risk perceptions and behaviours of people who prescribe, take or advise on opioids: physicians, patients and pharmacists. ...
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2018-12-04ZeitschriftenartikelExperimental studies addressing the longevity of Bacillus subtilis spores – The first data from a 500-year experiment The ability to form endospores allows certain Gram-positive bacteria (e.g. Bacillus subtilis) to challenge the limits of microbial resistance and survival. Thus, B. subtilis is able to tolerate many environmental extremes ...
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2010-03-29Teil eines BuchesExperimentelle Studien über die künstliche Abschwächung der Milzbrandbazillen und Milzbrandinfektion durch Fütterung
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2018-05-29ZeitschriftenartikelExpertise des Robert Koch-Instituts für den ersten Präventions- bericht: Hintergrund, Ziele und Herangehensweise
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2018-05-29ZeitschriftenartikelExpertise of the Robert Koch Institute for the first prevention report: background, aims and approach
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2021-02-02ZeitschriftenartikelExploring how Syrian women manage their health after migration to Germany: results of a qualitative study Background In the recent years, the number of Syrians living in Germany increased drastically due to the massive displacement caused by the Syrian conflict. Syrian migrant women in Germany are challenged by both the ...
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2018-04-16ZeitschriftenartikelExploring the effect of previous inactivated influenza vaccination on seasonal influenza vaccine effectiveness against medically attended influenza: Results of the European I‐MOVE multicentre test‐negative case‐control study, 2011/2012‐2016/2017 Background Results of previous influenza vaccination effects on current season influenza vaccine effectiveness (VE) are inconsistent. Objectives To explore previous influenza vaccination effects on current season VE ...
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2009-04-24ZeitschriftenartikelExploring the functional interaction between POSH and ALIX and the relevance to HIV-1 release Background: The ALG2-interacting protein X (ALIX)/AIP1 is an adaptor protein with multiple functions in intracellular protein trafficking that plays a central role in the biogenesis of enveloped viruses. The ubiquitin ...
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2016-11-15ZeitschriftenartikelExposure Patterns Driving Ebola Transmission in West Africa: A Retrospective Observational Study Background: The ongoing West African Ebola epidemic began in December 2013 in Guinea, probably from a single zoonotic introduction. As a result of ineffective initial control efforts, an Ebola outbreak of unprecedented ...
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2010-08-23BachelorarbeitExpression and purification of the primate foamy virus transmembrane envelope protein Seit dem Nachweis breit neutralisierender Antikörper (bNAb), welche von HIV-infizierten Menschen gebildet werden können, konzentrieren sich viele Ansätze auf die Induktion solcher Antikörper zur Entwicklung eines HIV ...
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2003-01-01ZeitschriftenartikelExpression of ICOS In Vivo Defines CD4+ Effector T Cells with High Inflammatory Potential and a Strong Bias for Secretion of Interleukin 10 The studies performed to date analyzed the overall participation of the inducible costimulator (ICOS) in model diseases, but did not yield information on the nature and function of ICOS-expressing T cells in vivo. We ...
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2020-10-06ZeitschriftenartikelExpression of in vivo biotinylated recombinant antigens SAG1 and SAG2A from Toxoplasma gondii for improved seroepidemiological bead-based multiplex assays Background Few bead-based multiplex assays have been described that detect antibodies against the protozoan parasite Toxoplasma gondii in large-scale seroepidemiological surveys. Moreover, each multiplex assay has ...
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2012-07-18ZeitschriftenartikelExpression of XCR1 characterizes the Batf3-dependent lineage of dendritic cells capable of antigen cross-presentation Cross-presentation of antigen by dendritic cells (DCs) to CD8+ T cells is a fundamentally important mechanism in the defense against pathogens and tumors. Due to the lack of an appropriate lineage marker, cross-presenting ...
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2009-06-01DiplomarbeitExpression rekombinanter, von HIV-1 gp41 abgeleiteter Proteine für die Analyse der Immunpathogenese Zur Etablierung eines Endotoxin-freien Bacillus megaterium Produktionssystems wurden zehn mittels PCR amplifizierte, von HIV-1 g41 abgeleitete Fragmente hergestellt und in transformations-kompetente B. megaterium Protoplasten ...
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2018-08-09BachelorarbeitExpression und Analyse retroviraler immunsuppressiver Doma nen auf humanen Zellen Eine Vielzahl von Retroviren sind in der Lage, das Immunsystem des Wirtes durch verschiedene Mechanismen zu beeinflussen. Die isu-Domäne als ein Teil der retroviralen TM-Proteine p15E (PERV, MuLV), sowie gp41 (HIV-1) ...
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2006-09-01DissertationExpression und biologische Funktion von humanen endogenen Retroviren (HERVs), insbesondere von HERV-K Daten des humanen Genomprojektes zeigen, dass ca. 8% des gesamten humanen Genoms aus retroviralen Sequenzen besteht. Der überwiegende Teil dieser Proviren ist aufgrund verschiedener Mutationen defekt. Im Gegensatz zu ...
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2005-09-01DiplomarbeitExpression von porzinen endogenen Retroviren in metastasierenden Melanomen und Melanomzelllinien von Troll Schweinen Porzine endogene Retroviren (PERVs) sind im Genom aller Schweine integriert. Ihre Expression in normalen porzinen Geweben sowie in Tumoren und ihre biologische Rolle ist bisher nicht ausführlich untersucht worden. Im ...
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2014-03-19ZeitschriftenartikelExpression-analysis of the human endogenous retrovirus HERV-K in human astrocytic tumors Background: The human endogenous retrovirus K (HERV-K) has been acquired by the genome of human ancestors million years ago. It is the most complete of the HERVs with transcriptionally active gag, pol and env genes. ...
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2015-10-14ZeitschriftenartikelExtended Microbiological Characterization of Göttingen Minipigs in the Context of Xenotransplantation: Detection and Vertical Transmission of Hepatitis E Virus Xenotransplantation has been proposed as a solution to the shortage of suitable human donors. Pigs are currently favoured as donor animals for xenotransplantation of cells, including islet cells, or organs. To reduce the ...