Auflistung nach Titel
Anzeige der Publikationen 10401-10420 von 11425
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2021-07-18ZeitschriftenartikelThe Neural Gut–Brain Axis of Pathological Protein Aggregation in Parkinson’s Disease and Its Counterpart in Peroral Prion Infections A neuropathological hallmark of Parkinson’s disease (PD) is the cerebral deposition of abnormally aggregated α-synuclein (αSyn). PD-associated αSyn (αSynPD) aggregates are assumed to act, in a prion-like manner, as ...
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2013-10-08ZeitschriftenartikelThe Novel Human Influenza A(H7N9) Virus Is Naturally Adapted to Efficient Growth in Human Lung Tissue A novel influenza A virus (IAV) of the H7N9 subtype has been isolated from severely diseased patients with pneumonia and acute respiratory distress syndrome and, apparently, from healthy poultry in March 2013 in Eastern ...
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2015-07-28ZeitschriftenartikelThe PadR-like transcriptional regulator LftR ensures efficient invasion of Listeria monocytogenes into human host cells Invasion of the bacterial pathogen Listeria monocytogenes into human host cells requires specialized surface molecules for attachment and induction of phagocytosis. However, efficient invasion is also dependent on factors ...
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2011-07-23ZeitschriftenartikelThe Pathology of Experimental Poxvirus Infection in Common Marmosets (Callithrix jacchus): Further Characterization of a New Primate Model for Orthopoxvirus Infections Zoonotic orthopoxvirus (OPV) can induce severe disease in man and the virus has potential for use in bioterrorism. New vaccines and therapeutics against OPV infections must be tested in animal models. The aim of this study ...
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2018-06-19ZeitschriftenartikelThe PGRS Domain of Mycobacterium tuberculosis PE_PGRS Protein Rv0297 Is Involved in Endoplasmic Reticulum Stress-Mediated Apoptosis through Toll-Like Receptor 4 The genome of Mycobacterium tuberculosis, the causal organism of tuberculosis (TB), encodes a unique protein family known as the PE/PPE/PGRS family, present exclusively in the genus Mycobacterium and nowhere else in the ...
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2011-12-23ZeitschriftenartikelThe phylogeny of yellow fever virus 17D vaccines In recent years the safety of the yellow fever live vaccine 17D came under scrutiny. The focus was on serious adverse events after vaccinations that resemble a wild type infection with yellow fever and whose reasons are ...
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2017-09-06ZeitschriftenartikelThe porcine virome and xenotransplantation The composition of the porcine virome includes viruses that infect pig cells, ancient virus-derived elements including endogenous retroviruses inserted in the pig chromosomes, and bacteriophages that infect a broad array ...
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2010-11-10ZeitschriftenartikelThe Presence of a vpu Gene and the Lack of Nef-Mediated Downmodulation of T Cell Receptor-CD3 Are Not Always Linked in Primate Lentiviruses Nef is an accessory protein critical for the ability of human and simian immunodeficiency viruses (HIV and SIV) to replicate efficiently in their respective hosts. Previous analyses of members of 15 different primate ...
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2011-04-14ZeitschriftenartikelThe proof of the pudding is in the eating: an outbreak of emetic syndrome after a kindergarten excursion, Berlin, Germany, December 2007 An outbreak of food poisoning (emetic syndrome) occurred in three kindergartens (A, B and C) in Berlin, Germany, on 3 December 2007 after an excursion during which food was served. We conducted a retrospective cohort study ...
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2015-06-04ZeitschriftenartikelThe Proteome of the Isolated Chlamydia trachomatis Containing Vacuole Reveals a Complex Trafficking Platform Enriched for Retromer Components Chlamydia trachomatis is an important human pathogen that replicates inside the infected host cell in a unique vacuole, the inclusion. The formation of this intracellular bacterial niche is essential for productive Chlamydia ...
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2013-05-23ZeitschriftenartikelThe resuscitation promotion concept extends to firmicutes
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2019-08-28ZeitschriftenartikelThe rise in vancomycin-resistant Enterococcus faecium in Germany: data from the German Antimicrobial Resistance Surveillance (ARS) Background Due to limited therapeutic options, vancomycin-resistant Enterococcus faecium (VREF) is of great clinical significance. Recently, rising proportions of vancomycin resistance in enterococcal infections have been ...
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2012-04-19ZeitschriftenartikelThe risk of AIDS-defining events is decreasing over time in the German HIV-1 Seroconverter Cohort Background: With ageing of the HIV-infected population, long-term exposure to treatment, varying adherence, emerging resistance and complications to therapies, effectiveness of Highly Active Antiretroviral Therapy (HAART) ...
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2018-06-26ZeitschriftenartikelThe RNA Helicase DDX6 Associates with RIG-I to Augment Induction of Antiviral Signaling Virus infections induce sensitive antiviral responses within the host cell. The RNA helicase retinoic acid-inducible gene I (RIG-I) is a key sensor of influenza virus RNA that induces the expression of antiviral type I ...
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2017-04-25Berichte und sonstige TexteThe Robert Koch Institute at a Glance
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2016-06-16Berichte und sonstige TexteThe Robert Koch Institute - A Historical Retrospective
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2014-03-01BachelorarbeitThe Role of CD63-Large Extracellular Loop on HIV-1 entry and cell to cell transfer Regarding to the World Health Organization’s 2011 published list of the top ten causes of death worldwide, HIV/ AIDS is still listed as the 6th most frequent reason for fatality. Previous analyses with a Yeast two-hybrid ...
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2012-01-26ZeitschriftenartikelThe role of facemasks and hand hygiene in the prevention of influenza transmission in households: results from a cluster randomised trial; Berlin, Germany, 2009-2011 Background: Previous controlled studies on the effect of non-pharmaceutical interventions (NPI) - namely the use of facemasks and intensified hand hygiene - in preventing household transmission of influenza have not ...
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2021-06-24DissertationThe role of human SAMHD1 in restricting porcine endogenous retroviruses (PERVs) and the innate immune response to PERV infection in human primary immune cells Die Freisetzung von Porcinen Endogenen Retroviren (PERVs) aus Schweinezellen ist ein potenzieller Risikofaktor während der Xenotransplantation. PERV ist in der Lage, in humanen Zelllinien zu replizieren. Mögliche ...
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2022-01-22ZeitschriftenartikelThe role of personality traits and social support in relations of health-related behaviours and depressive symptoms Background: Previous evidence has suggested that physically inactive individuals and extensive media users are at high risk for experiencing depressive symptoms. We examined personality traits and perceived social support ...