Auflistung nach Schlagwort "Molecular"
Anzeige der Publikationen 1-12 von 12
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2009-09-30ZeitschriftenartikelBeneficial and detrimental effects of human endogenous retroviruses In this mini review, we aim to evaluate the structure and function of Human Endogenous Retroviruses (HERVs) with respect to the benefit they may have for humans or the damage they may cause. Emphasis is laid on their ...
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2009-02-09ZeitschriftenartikelCharacterisation of porin genes from Mycobacterium fortuitum and their impact on growth Background: Highly pathogenic mycobacteria like Mycobacterium tuberculosis are characterised by their slow growth and their ability to reside and multiply in the very hostile phagosomal environment and a correlation ...
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2016-01-12ZeitschriftenartikelExternal quality assessment studies for laboratory performance of molecular and serological diagnosis of Chikungunya virus infection Background: Since the re-emergence of Chikungunya virus (CHIKV) in Reunion in 2005 and the recent outbreak in the Caribbean islands with an expansion to the Americas the CHIK diagnostic became very important. Objectives: ...
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2015-05-30ZeitschriftenartikelFirst international external quality assessment of molecular diagnostics for Mers-CoV Background: Since the discovery of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012, diagnostic protocols were quickly published and deployed globally. Objectives: We set out to assess the quality of ...
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2005-01-24ZeitschriftenartikelGenetical and functional investigation of fliC genes encoding flagellar serotype H4 in wildtype strains of Escherichia coli and in a laboratory E. coli K-12 strain expressing flagellar antigen type H48 Background: Serotyping of O-(lipopolysaccharide) and H-(flagellar) antigens is a wideley used method for identification of pathogenic strains and clones of Escherichia coli. At present, 176 O- and 53 H-antigens are ...
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2010-01-15ZeitschriftenartikelHuman Coronavirus NL63 Open Reading Frame 3 encodes a virion-incorporated N-glycosylated membrane protein Background: Human pathogenic coronavirus NL63 (hCoV-NL63) is a group 1 (alpha) coronavirus commonly associated with respiratory tract infections. In addition to known non-structural and structural proteins all coronaviruses ...
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2009-12-21ZeitschriftenartikelIdentification of a novel betaherpesvirus in Mus musculus Rodent betaherpesviruses vary considerably in genomic content, and these variations can result in a distinct pathogenicity. Therefore, the identification of unknown betaherpesviruses in house mice (Mus musculus), the ...
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2009-11-18ZeitschriftenartikelLymphocryptovirus phylogeny and the origins of Epstein-Barr virus. Specimens from wild and captive primates were collected, and searched for new members of the genus Lymphocryptovirus (subfamily Gammaherpesvirinae) utilising PCR for the DNA polymerase gene. Twenty-one new viruses were ...
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2010-09-14ZeitschriftenartikelPhylogenetic history demonstrates two different lineages of dengue type 1 virus in Colombia Background: Dengue Fever is one of the most important viral re-emergent diseases affecting about 50 million people around the world especially in tropical and sub-tropical countries. In Colombia, the virus was first ...
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2009-05-20ZeitschriftenartikelTracing the HIV-1 subtype B mobility in Europe: a phylogeographic approach Background: The prevalence and the origin of HIV-1 subtype B, the most prevalent circulating clade among the long-term residents in Europe, have been studied extensively. However the spatial diffusion of the epidemic ...
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2009-01-08ZeitschriftenartikelTyping Clostridium difficile strains based on tandem repeat sequences Background: Genotyping of epidemic Clostridium difficile strains is necessary to track their emergence and spread. Portability of genotyping data is desirable to facilitate inter-laboratory comparisons and epidemiological ...
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2005-06-20ZeitschriftenartikelViral promoters can initiate expression of toxin genes introduced into Escherichia coli Background: The expression of recombinant proteins in eukaryotic cells requires the fusion of the coding region to a promoter functional in the eukaryotic cell line. Viral promoters are very often used for this purpose. ...