2022-12-15Zeitschriftenartikel
Increase in NDM-1 and NDM-1/OXA-48-producing Klebsiella pneumoniae in Germany associated with the war in Ukraine, 2022
Sandfort, Mirco
Hans, Jörg B.
Fischer, Martin A.
Reichert, Felix
Cremanns, Martina
Eisfeld, Jessica
Pfeifer, Yvonne
Heck, Annika
Eckmanns, Tim
Werner, Guido
Gatermann, Sören
Haller, Sebastian
Pfennigwerth, Nils
In 2022, German surveillance systems observed rapidly increasing numbers of NDM-1- and NDM-1/OXA-48-producing Klebsiella pneumoniae, which may in part reflect recurring pre-pandemic trends. Among these cases, however, a presence in Ukraine before diagnosis was frequently reported. Whole genome sequencing of 200 isolates showed a high prevalence of sequence types ST147, ST307, ST395 and ST23, including clusters corresponding to clonal dissemination and suggesting onward transmission in Germany. Screening and isolation of patients from Ukraine may help avoid onward transmission.