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2010-12-08Zeitschriftenartikel DOI: 10.1093/jinfdis/jiq055
Clinical Outcome of HIV-Infected Patients with Discordant Virological and Immunological Response to Antiretroviral Therapy
dc.contributor.authorZoufaly, Alexander
dc.contributor.authorHeiden, Matthias an der
dc.contributor.authorKollan, Christian
dc.contributor.authorBogner, Johannes
dc.contributor.authorFätkenheuer, G.
dc.contributor.authorWasmuth, J. C.
dc.contributor.authorStoll, Matthias
dc.contributor.authorHamouda, Osamah
dc.contributor.authorLunzen, Jan van
dc.date.accessioned2018-05-07T15:39:59Z
dc.date.available2018-05-07T15:39:59Z
dc.date.created2012-05-02
dc.date.issued2010-12-08none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/reV8ZjtgFuwU2/PDF/22z6SJ4Yj8fgE.pdf
dc.identifier.urihttp://edoc.rki.de/176904/1222
dc.description.abstractBackground: A subgroup of human immunodeficiency virus type 1 (HIV-1)–infected patients with severe immunodeficiency show persistently low CD4+ cell counts despite sustained viral suppression. It is unclear whether this immuno-virological discordance translates into an increased risk for clinical events. Methods: Data analysis from a large multicenter cohort incorporating 14,433 HIV-1–infected patients in Germany. Treatment-naive patients beginning antiretroviral therapy (ART) with CD4+ cell countseng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Infektionsepidemiologie
dc.subjectAdulteng
dc.subjectHumanseng
dc.subjectFemaleeng
dc.subjectMaleeng
dc.subjectCohort Studieseng
dc.subjectCD4 Lymphocyte Counteng
dc.subjectHIV Infections/immunologyeng
dc.subjectHIV Infections/drug therapyeng
dc.subjectProportional Hazards Modelseng
dc.subjectAnti-HIV Agents/therapeutic useeng
dc.subjectHIV Infections/virologyeng
dc.subjectMiddle Agedeng
dc.subject.ddc610 Medizin
dc.titleClinical Outcome of HIV-Infected Patients with Discordant Virological and Immunological Response to Antiretroviral Therapy
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10024345
dc.identifier.doi10.1093/jinfdis/jiq055
dc.identifier.doihttp://dx.doi.org/10.25646/1147
local.edoc.container-titleJournal of Infectious Diseases
local.edoc.container-textZoufaly, A., An Der Heiden, M., Kollan, C., Bogner, J.R., Fätkenheuer, G., Wasmuth, J.C., Stoll, M., Hamouda, O., Van Lunzen, J. Clinical outcome of HIV-infected patients with discordant virological and immunological response to antiretroviral therapy (2011) Journal of Infectious Diseases, 203 (3), pp. 364-371.
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://jid.oxfordjournals.org/content/203/3/364
local.edoc.container-publisher-nameOxford University Press
local.edoc.container-volume203
local.edoc.container-issue3
local.edoc.container-year2011

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