Antigenic Characterization of Novel Human Norovirus GII.4 Variants San Francisco 2017 and Hong Kong 2019

Tohma, Kentaro; Landivar, Michael; Ford-Siltz, Lauren A.; Pilewski, Kelsey A.; Kendra, Joseph A.; Niendorf, Sandra; Parra, Gabirel I.

2024-04-17Zeitschriftenartikel

Tohma, Kentaro

Landivar, Michael

Ford-Siltz, Lauren A.

Pilewski, Kelsey A.

Kendra, Joseph A.

Niendorf, Sandra

Parra, Gabirel I.

Norovirus is a major cause of acute gastroenteritis; GII.4 is the predominant strain in humans. Recently, 2 new GII.4 variants, Hong Kong 2019 and San Francisco 2017, were reported. Characterization using GII.4 monoclonal antibodies and serum demonstrated different antigenic profiles for the new variants compared with historical variants.

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