Zur Kurzanzeige

2015-06-01Zeitschriftenartikel DOI: 10.1038/srep10734
Automated Pipeline for Purification, Biophysical and X-Ray Analysis of Biomacromolecular Solutions
dc.contributor.authorGraewert, Melissa A.
dc.contributor.authorFranke, Daniel
dc.contributor.authorJeffries, Cy M.
dc.contributor.authorBlanchet, Clement E.
dc.contributor.authorRuskule, Darja
dc.contributor.authorKuhle, Katja
dc.contributor.authorFlieger, Antje
dc.contributor.authorSchäfer, Bernd
dc.contributor.authorTartsch, Bernd
dc.contributor.authorMeijers, Rob
dc.contributor.authorSvergun, Dmitri I.
dc.date.accessioned2018-05-07T18:19:02Z
dc.date.available2018-05-07T18:19:02Z
dc.date.created2015-07-03
dc.date.issued2015-06-01none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/rebX7yQ2JYZgk/PDF/21VCShvaY6MOI.pdf
dc.identifier.urihttp://edoc.rki.de/176904/2085
dc.description.abstractSmall angle X-ray scattering (SAXS), an increasingly popular method for structural analysis of biological macromolecules in solution, is often hampered by inherent sample polydispersity. We developed an all-in-one system combining in-line sample component separation with parallel biophysical and SAXS characterization of the separated components. The system coupled to an automated data analysis pipeline provides a novel tool to study difficult samples at the P12 synchrotron beamline (PETRA-3, EMBL/DESY, Hamburg).eng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Infektionskrankheiten / Erreger
dc.subjectScattering Small Angleeng
dc.subjectBiophysics/methodseng
dc.subjectMacromolecular Substances/chemistryeng
dc.subjectMacromolecular Substances/isolation & purificationeng
dc.subjectSolutions/chemistryeng
dc.subject.ddc610 Medizin
dc.titleAutomated Pipeline for Purification, Biophysical and X-Ray Analysis of Biomacromolecular Solutions
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10039851
dc.identifier.doi10.1038/srep10734
dc.identifier.doihttp://dx.doi.org/10.25646/2010
local.edoc.container-titleScientific Reports
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://www.nature.com/srep/2015/150601/srep10734/full/srep10734.html
local.edoc.container-publisher-nameNature Publishing Group
local.edoc.container-volume5
local.edoc.container-issue10734
local.edoc.container-year2015

Zur Kurzanzeige