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Browsing Artikel in Fachzeitschriften by Author "Dabrowski, Piotr Wojtek"
Now showing items 1-20 of 26
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2017-09-18ZeitschriftenartikelA novel Coltivirus-related virus isolated from free-tailed bats from Côte d’Ivoire is able to infect human cells in vitro Weiss, Sabrina; Dabrowski, Piotr Wojtek; Kurth, Andreas; Leendertz, Siv Aina J.; Leendertz, Fabian H.Background: Zoonotic transmission events play a major role in the emergence of novel diseases. While such events are virtually impossible to predict, wildlife screening for potential emerging pathogens can be a first ...
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2017-10-01ZeitschriftenartikelBerlin Squirrelpox Virus, a New Poxvirus in Red Squirrels, Berlin, Germany Wibbelt, Gudrun; Tausch, Simon H.; Dabrowski, Piotr Wojtek; Kershaw, Olivia; Nitsche, Andreas; Schrick, LiviaNear Berlin, Germany, several juvenile red squirrels (Sciurus vulgaris) were found with moist, crusty skin lesions. Histology, electron microscopy, and cell culture isolation revealed an orthopoxvirus-like infection. ...
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2015-04-02ZeitschriftenartikelComparative Genomic Analysis of Two Novel Sporadic Shiga Toxin-Producing Escherichia coli O104:H4 Strains Isolated 2011 in Germany Tietze, Erhard; Dabrowski, Piotr Wojtek; Prager, Rita; Radonić, Aleksandar; Fruth, Angelika; Aurass, Philipp; Nitsche, Andreas; Mielke, Martin; Flieger, AntjeA large outbreak of gastrointestinal disease occurred in 2011 in Germany which resulted in almost 4000 patients with acute gastroenteritis or hemorrhagic colitis, 855 cases of a hemolytic uremic syndrome and 53 deaths. The ...
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2015-10-15ZeitschriftenartikelComparison of 454 Ultra-Deep Sequencing and Allele-Specific Real-Time PCR with Regard to the Detection of Emerging Drug-Resistant Minor HIV-1 Variants after Antiretroviral Prophylaxis for Vertical Transmission Hauser, Andrea; Kücherer, Claudia; Kunz, Andrea; Dabrowski, Piotr Wojtek; Radonić, Aleksandar; Nitsche, Andreas; Theuring, Stefanie; Bannert, Norbert; Sewangi, Julius; Mbezi, Paulina; Dugange, Festo; Harms, Gundel; Meixenberger, KarolinBackground: Pregnant HIV-infected women were screened for the development of HIV-1 drug resistance after implementation of a triple-antiretroviral transmission prophylaxis as recommended by the WHO in 2006. The study ...
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2013-02-20ZeitschriftenartikelComparison of host cell gene expression in cowpox, monkeypox or vaccinia virus-infected cells reveals virus-specific regulation of immune response genes Bourquain, Daniel; Dabrowski, Piotr Wojtek; Nitsche, AndreasBackground: Animal-borne orthopoxviruses, like monkeypox, vaccinia and the closely related cowpox virus, are all capable of causing zoonotic infections in humans, representing a potential threat to human health. The ...
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2015-03-12ZeitschriftenartikelComprehensive molecular, genomic and phenotypic analysis of a major clone of Enterococcus faecalis MLST ST40 Zischka, Melanie; Künne, Carsten T.; Blom, Jochen; Wobser, Dominique; Sakιnç, Türkân; Schmidt-Hohagen, Kerstin; Dabrowski, Piotr Wojtek; Nitsche, Andreas; Hübner, Johannes; Hain, Torsten; Chakraborty, Trinad; Linke, Burkhard; Goesmann, Alexander; Voget, Sonja; Daniel, Rolf; Schomburg, Dietmar; Hauck, Rüdiger; Hafez, Hafez M.; Tielen, Petra; Bender, Jennifer K.; Steglich, Matthias; Nübel, Ulrich; Witte, Wolfgang; Werner, GuidoBackground: Enterococcus faecalis is a multifaceted microorganism known to act as a beneficial intestinal commensal bacterium. It is also a dreaded nosocomial pathogen causing life-threatening infections in hospitalised ...
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2015-07-23ZeitschriftenartikelDraft Genome Sequences of Klebsiella oxytoca Isolates Originating from a Highly Contaminated Liquid Hand Soap Product Hammerl, J. A.; Lasch, Peter; Nitsche, Andreas; Dabrowski, Piotr Wojtek; Hahmann, H.; Wicke, Amal; Kleta, S.; Dahouk, Sascha Al; Dieckmann, R.In 2013, contaminated liquid soap was detected by routine microbiological monitoring of consumer products through state health authorities. Because of its high load of Klebsiella oxytoca, the liquid soap was notified via ...
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2014-05-14ZeitschriftenartikelFatal Monkeypox in Wild-Living Sooty Mangabey, Côte d’Ivoire, 2012 Radonić, Aleksandar; Metzger, Sonja; Dabrowski, Piotr Wojtek; Couacy-Hymann, Emmanuel; Schünadel, Livia; Kurth, Andreas; Mätz-Rensing, Kerstin; Boesch, Christophe; Leendertz, Fabian; Nitsche, AndreasWe isolated a monkeypox virus from a wild-living monkey, a sooty mangabey, found dead in Taï National Park, Côte d’Ivoire, in March 2012. The whole-genome sequence obtained from this isolate and directly from clinical ...
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2020-12-24ZeitschriftenartikelFirst detection of bat-borne Issyk-Kul virus in Europe Brinkmann, Annika; Kohl, Claudia; Radonić, Aleksandar; Dabrowski, Piotr Wojtek; Mühldorfer, Kristin; Nitsche, Andreas; Wibbelt, Gudrun; Kurth, AndreasBats have been gaining attention as potential reservoir hosts of numerous viruses pathogenic to animals and man. Issyk-Kul virus, a member of the family Nairoviridae, was first isolated in the 1970s from vespertilionid ...
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2015-09-24ZeitschriftenartikelFirst Draft Genome Sequence of Balamuthia mandrillaris, the Causative Agent of Amoebic Encephalitis Detering, H.; Aebischer, Toni; Dabrowski, Piotr Wojtek; Radonić, Aleksandar; Nitsche, Andreas; Renard, Bernhard Y.; Kiderlen, AlbrechtThe free-living amoeba Balamuthia mandrillaris is a rare but highly lethal agent of amoebic encephalitis in humans and many other mammalian species. Here, we announce the first draft genome sequence of the original 1990 ...
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2011-11-30ZeitschriftenartikelGenome analysis of bat adenovirus 2: Indications of interspecies transmission Kohl, Claudia; Vidovszky, Márton Z.; Mühldorfer, Kristin; Dabrowski, Piotr Wojtek; Radonić, Aleksandar; Nitsche, Andreas; Wibbelt, Gudrun; Kurth, Andreas; Harrach, BalázsThe genome of bat adenovirus 2 was sequenced and analyzed. It is similar in size (31,616 bp) to the genomes of bat adenovirus 3 and canine adenoviruses 1 and 2. These four viruses are monophyletic and share an identical ...
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2013-12-03ZeitschriftenartikelGenome-Wide Comparison of Cowpox Viruses Reveals a New Clade Related to Variola Virus Dabrowski, Piotr Wojtek; Radonić, Aleksandar; Kurth, Andreas; Nitsche, AndreasZoonotic infections caused by several orthopoxviruses (OPV) like monkeypox virus or vaccinia virus have a significant impact on human health. In Europe, the number of diagnosed infections with cowpox viruses (CPXV) is ...
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2014-12-30ZeitschriftenartikelInvestigating the zoonotic origin of the West African Ebola epidemic Saéz, Almudena Marí; Weiss, Sabrina; Nowak, Kathrin; Lapeyre, Vincent; Zimmermann, Fee; Düx, Ariane; Kühl, Hjalmar S.; Kaba, Moussa; Regnaut, Sebastien; Merkel, Kevin; Sachse, Andreas; Thiesen, Ulla; Villányi, Lili; Boesch, Christophe; Dabrowski, Piotr Wojtek; Radonić, Aleksandar; Nitsche, Andreas; Leendertz, Siv Aina J.; Petterson, Stefan; Becker, Stephan; Schaade, Lars; Fahr, Jakob; Gogarten, Jan F.; Calvignac-Spencer, Sébastien; Leendertz, FabianThe severe Ebola virus disease epidemic occurring in West Africa stems from a single zoonotic transmission event to a 2‐year‐old boy in Meliandou, Guinea. We investigated the zoonotic origins of the epidemic using wildlife ...
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2015-02-06ZeitschriftenartikelIsolation and Functional Characterization of the Novel Clostridium botulinum Neurotoxin A8 Subtype Kull, Skadi; Schulz, Melanie; Strotmeier, Jasmin Weisemann née; Kirchner, Sebastian; Schreiber, Tanja; Bollenbach, Alexander; Dabrowski, Piotr Wojtek; Nitsche, Andreas; Kalb, Suzanne R.; Dorner, Martin; Barr, John R.; Rummel, Andreas; Dorner, BrigitteBotulism is a severe neurological disease caused by the complex family of botulinum neurotoxins (BoNT). Based on the different serotypes known today, a classification of serotype variants termed subtypes has been proposed ...
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2012-06-04ZeitschriftenartikelmPSQed: A Software for the Design of Multiplex Pyrosequencing Assays. Dabrowski, Piotr Wojtek; Nitsche, AndreasMolecular-based diagnostic assays are the gold standard for infectious diseases today, since they allow a rapid and sensitive identification and typing of various pathogens. While PCR can be designed to be specific for a ...
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2013-03-26ZeitschriftenartikelMultiPSQ: A Software Solution for the Analysis of Diagnostic n-Plexed Pyrosequencing Reactions Dabrowski, Piotr Wojtek; Schröder, Kati; Nitsche, AndreasBackground: Pyrosequencing can be applied for Single-Nucleotide-Polymorphism (SNP)-based pathogen typing or for providing sequence information of short DNA stretches. However, for some pathogens molecular typing cannot ...
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2013-06-01ZeitschriftenartikelNovel Mycobacterium tuberculosis Complex Isolate from a Wild Chimpanzee Coscolla, Mireia; Lewin, Astrid; Metzger, Sonja; Mätz-Rennsing, Kerstin; Calvignac-Spencer, Sébastien; Nitsche, Andreas; Dabrowski, Piotr Wojtek; Radonić, Aleksandar; Niemann, Stefan; Parkhill, Julian; Couacy-Hymann, Emmanuel; Feldman, Julia; Comas, Iñaki; Boesch, Christophe; Gagneux, Sebastien; Leendertz, FabianTuberculosis (TB) is caused by gram-positive bacteria known as the Mycobacterium tuberculosis complex (MTBC). MTBC include several human-associated lineages and several variants adapted to domestic and, more rarely, wild ...
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2018-09-08ZeitschriftenartikelPAIPline: pathogen identification in metagenomic and clinical next generation sequencing samples Andrusch, Andreas; Dabrowski, Piotr Wojtek; Klenner, Jeanette; Tausch, Simon H.; Kohl, Claudia; Osman, Abdalla A.; Renard, Bernhard Y.; Nitsche, AndreasMotivation: Next generation sequencing (NGS) has provided researchers with a powerful tool to characterize metagenomic and clinical samples in research and diagnostic settings. NGS allows an open view into samples useful ...
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2014-06-15ZeitschriftenartikelPipasic: similarity and expression correction for strain-level identification and quantification in metaproteomics Penzlin, Anke; Lindner, Martin S.; Döllinger, Jörg; Dabrowski, Piotr Wojtek; Nitsche, Andreas; Renard, Bernhard Y.Motivation: Metaproteomic analysis allows studying the interplay of organisms or functional groups and has become increasingly popular also for diagnostic purposes. However, difficulties arise owing to the high sequence ...
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2014-12-15ZeitschriftenartikelProtocol for Metagenomic Virus Detection in Clinical Specimens Kohl, Claudia; Brinkmann, Annika; Dabrowski, Piotr Wojtek; Radonić, Aleksandar; Nitsche, Andreas; Kurth, AndreasSixty percent of emerging viruses have a zoonotic origin, making transmission from animals a major threat to public health. Prompt identification and analysis of these pathogens are indispensable to taking action toward ...