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Browsing Artikel in Fachzeitschriften by Author "Flieger, Antje"
Now showing items 1-20 of 36
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2019-01-16ZeitschriftenartikelA Listeria monocytogenes ST2 clone lacking chitinase ChiB from an outbreak of non-invasive gastroenteritis Halbedel, Sven; Prager, Rita; Kleta, Sylvia; Trost, Eva; Nishanth, Gopala; Alles, Georg; Hölzel, Christina; Schlesiger, Friederike; Pietzka, Ariane; Schlüter, Dirk; Flieger, Antje; Banerji, SangeetaAn outbreak with a remarkable Listeria monocytogenes clone causing 163 cases of non-invasive listeriosis occurred in Germany in 2015. Core genome multi locus sequence typing grouped non-invasive outbreak isolates and ...
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2020-06-26Berichte und sonstige TexteAuthor Correction: Genome-based Salmonella serotyping as the new gold standard Banerji, Sangeeta; Simon, Sandra; Tille, Andreas; Fruth, Angelika; Flieger, Antje
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2015-06-01ZeitschriftenartikelAutomated Pipeline for Purification, Biophysical and X-Ray Analysis of Biomacromolecular Solutions Graewert, Melissa A.; Franke, Daniel; Jeffries, Cy M.; Blanchet, Clement E.; Ruskule, Darja; Kuhle, Katja; Flieger, Antje; Schäfer, Bernd; Tartsch, Bernd; Meijers, Rob; Svergun, Dmitri I.Small angle X-ray scattering (SAXS), an increasingly popular method for structural analysis of biological macromolecules in solution, is often hampered by inherent sample polydispersity. We developed an all-in-one system ...
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2009-05-01ZeitschriftenartikelbdhA-patD operon as a virulence determinant, revealed by a novel large-scale approach for identification of Legionella pneumophila mutants defective for amoeba infection. Aurass, Philipp; Pless, Birgit; Rydzewski, Kerstin; Holland, Gudrun; Bannert, Norbert; Flieger, AntjeLegionella pneumophila, the causative agent of Legionnaires' disease, is an intracellular parasite of eukaryotic cells. In the environment, it colonizes amoebae. After being inhaled into the human lung, the bacteria infect ...
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2012-11-21ZeitschriftenartikelCarrier prevalence, secondary household transmission and long-term shedding in two districts during the Escherichia coli O104:H4 outbreak in Germany, 2011 Sin, Muna Abu; Takla, Anja; Flieger, Antje; Prager, Rita; Fruth, Angelika; Tietze, Erhard; Fink, Eckhart; Korte, Jutta; Schink, Susanne; Höhle, Michael; Eckmanns, TimBackground: From May-July 2011, Germany experienced a large Shiga toxin-producing E. coli (STEC) O104:H4 outbreak. Our objective was to identify the prevalence of STEC O104:H4 carriers in households in highly affected ...
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2011-02-20ZeitschriftenartikelCharacterisation of Legionella pneumophila phospholipases and their impact on host cells Lang, Christina; Flieger, AntjePhospholipases are a diverse class of enzymes produced both by eukaryotic hosts and their pathogens. Major insights into action pathways of bacterial phospholipases have been provided during the last years. On the one hand ...
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2021-02-04ZeitschriftenartikelClosed Genome Sequences of Clinical Listeria monocytogenes PCR Serogroup IVb Isolates Associated with Two Recent Large Listeriosis Outbreaks in Germany Halbedel, Sven; Fischer, Martin A.; Thürmer, Andrea; Flieger, AntjeHere, we report the closed genome sequences of two representative Listeria monocytogenes strains belonging to PCR serogroup IVb, which are related to two large outbreaks of human listeriosis that affected Germany in 2015 ...
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2015-04-02ZeitschriftenartikelComparative Genomic Analysis of Two Novel Sporadic Shiga Toxin-Producing Escherichia coli O104:H4 Strains Isolated 2011 in Germany Tietze, Erhard; Dabrowski, Piotr Wojtek; Prager, Rita; Radonić, Aleksandar; Fruth, Angelika; Aurass, Philipp; Nitsche, Andreas; Mielke, Martin; Flieger, AntjeA large outbreak of gastrointestinal disease occurred in 2011 in Germany which resulted in almost 4000 patients with acute gastroenteritis or hemorrhagic colitis, 855 cases of a hemolytic uremic syndrome and 53 deaths. The ...
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2021-05-06ZeitschriftenartikelComplete Genome Sequences of Three Clinical Listeria monocytogenes Sequence Type 8 Strains from Recent German Listeriosis Outbreaks Fischer, Martin A.; Thürmer, Andrea; Flieger, Antje; Halbedel, SvenWe report here the closed genome sequences of three clinical Listeria monocytogenes strains of multilocus sequence typing (MLST) sequence type 8 (ST8). These strains are representatives of three separate listeriosis outbreak ...
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2023-02-02ZeitschriftenartikelCOVID-19-Pandemie führte zu starkem Rückgang von darmpathogenen Erregern Fruth, Angelika; Simon, Sandra; Halbedel, Sven; Banerji, Sangeeta; Flieger, AntjeIm Zuge der im März 2020 zur Bewältigung der COVID-19-Pandemie ergriffenen Infektionsschutzmaßnahmen wurde nicht nur ein abrupter Rückgang von Atemwegserkrankungen beobachtet, sondern im Verlauf des Jahres auch ein in ...
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2017-11-24ZeitschriftenartikelDisulfide loop cleavage of Legionella pneumophila PlaA boosts lysophospholipase A activity Lang, Christina; Hiller, Miriam; Flieger, AntjeL. pneumophila, an important facultative intracellular bacterium, infects the human lung and environmental protozoa. At least fifteen phospholipases A (PLA) are encoded in its genome. Three of which, namely PlaA, PlaC, and ...
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2011-09-27ZeitschriftenartikelEHEC/EAEC O104:H4 strain linked with the 2011 German outbreak of haemolytic uremic syndrome enters into the viable but non-culturable state in response to various stresses and resuscitates upon stress relief Aurass, Philipp; Prager, Rita; Flieger, AntjeVarious non-spore forming bacteria, including Escherichia coli, enter a dormant-like state, the viable but non-culturable (VBNC) state, characterized by the presence of viable cells but the inability to grow on routine ...
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2012-02-16ZeitschriftenartikelExperiences from the Shiga toxin-producing Escherichia coli O104:H4 outbreak in Germany and research needs in the field, Berlin, 28–29 November 2011 Stark, Klaus; Bauerfeind, Rolf; Bernard, Helen; Eckmanns, Tim; Ethelberg, Steen; Flieger, Antje; Giesecke, J.; Greiner, M.; Karch, Helge; Krause, Gérard; Mielke, Martin; O'Brien, S. J.; Pulz, M.; Scheutz, F.; Schielke, Anika; Stahl, R. A.; Takkinen, J.; Tarr, Phillip I.; Tauxe, R. V.; Werber, DirkThis report presents the main findings from an international workshop on Shiga toxin-producing Escherichia coli (STEC), held on 28–29 November 2011, organised by the Robert Koch Institute [1]. The workshop assembled ...
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2019-05-06ZeitschriftenartikelFluoroquinolone-Resistant Salmonella enterica, Campylobacter spp., and Arcobacter butzleri from Local and Imported Poultry Meat in Kumasi, Ghana Dekker, Denise; Eibach, Daniel; Boahen, Kennedy G.; Akenten, Charity Wiafe; Pfeifer, Yvonne; Zautner, Andreas E.; Mertens, Eva; Krumkamp, Ralf; Jaeger, Anna; Flieger, Antje; Owusu-Dabo, Ellis; May, JürgenSalmonella and Campylobacter are important gastroenteric pathogens. Arcobacter butzleri is an emerging enteric pathogen. Data on the frequencies of these poultry-associated pathogens on meat products sold in sub-Saharan ...
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2017-06-08ZeitschriftenartikelGenome Sequence of Paracoccus contaminans LMG 29738T, Isolated from a Water Microcosm Aurass, Philipp; Karste, Susanne; Trost, Eva; Glaeser, Stefanie P.; Kämpfer, Peter; Flieger, AntjeWe announce here the complete genome sequence of Paracoccus contaminans LMG 29738T, which we recently isolated from a contaminated water microcosm. The genome consists of a 2.94-Mb chromosome and a 94-kb plasmid. To our ...
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2020-03-09ZeitschriftenartikelGenome-based Salmonella serotyping as the new gold standard Banerji, Sangeeta; Simon, Sandra; Tille, Andreas; Fruth, Angelika; Flieger, AntjeSalmonella enterica is the second most reported bacterial cause of food-borne infections in Europe. Therefore molecular surveillance activities based on pathogen subtyping are an important measure of controlling Salmonellosis ...
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2021-05-14ZeitschriftenartikelGenome‑wide insights into population structure and host specifcity of Campylobacter jejuni Epping, Lennard; Walther, Birgit; Piro, Rosario M.; Knüver, Marie‑Theres; Huber, Charlotte; Thürmer, Andrea; Flieger, Antje; Fruth, Angelika; Janecko, Nicol; Wieler, Lothar H.; Stingl, Kerstin; Semmler, TorstenThe zoonotic pathogen Campylobacter jejuni is among the leading causes of foodborne diseases worldwide. While C. jejuni colonises many wild animals and livestock, persistence mechanisms enabling the bacterium to adapt to ...
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2021-08-19ZeitschriftenartikelIntensivierte genombasierte Surveillance von Campylobacter-Isolaten humaner Erkrankungsfälle in Deutschland Banerji, Sangeeta; Fruth, Angelika; Flieger, AntjeCampylobacter ist ein wichtiger Infektionserreger des Menschen und die Campylobacteriose stellt die häufigste meldepflichtige bakterielle Zoonose in Europa dar. In Deutschland werden jährlich ca. 60.000 Erkrankungsfälle ...
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2010-07-08ZeitschriftenartikelLegionella pneumophila induces human beta Defensin-3 in pulmonary cells Scharf, Stefanie; Vardarova, Kremena; Lang, Friederike; Schmeck, Bernd; Opitz, Bastian; Flieger, Antje; Heuner, Klaus; Hippenstiel, Stefan; Suttorp, Norbert; N'Guessan, Philippe DBackground: Legionella pneumophila is an important causative agent of severe pneumonia in humans. Human alveolar epithelium and macrophages are effective barriers for inhaled microorganisms and actively participate in the ...
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2019-10-09ZeitschriftenartikelListeriose-Ausbruch mit Listeria monocytogenes Sequenz-Cluster-Typ 2521 (Sigma1)in Deutschland Wilking, Hendrik; Lachmann, Raskit; Holzer, Alexandra; Boone, Idesbald; Halbedel, Sven; Flieger, Antje; Stark, KlausMittels Genomsequenzierung wurde im Jahr 2018 ein Listeriose-Cluster mit dem Listerien-Sequenz-Cluster-Typ 2521 im Konsiliarlabor für Listerien im RKI identifiziert. Es besteht nach IfSG eine Labormeldepflicht für L. ...