Browsing Artikel in Fachzeitschriften by Title
Now showing items 2183-2202 of 4575
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2010-09-27ZeitschriftenartikelImproved Detection of Mutated Human Cytomegalovirus UL97 by Pyrosequencing Ganciclovir (GCV) resistance frequently occurs upon prolonged treatment of ongoing active human cytomegalovirus (HCMV) infection in individuals with immature or compromised immune functions (e.g., recipients of solid-organ ...
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2014-06-03ZeitschriftenartikelImproved Testing of Recent HIV-1 Infections with the BioRad Avidity Assay Compared to the Limiting Antigen Avidity Assay and BED Capture Enzyme Immunoassay: Evaluation Using Reference Sample Panels from the German Seroconverter Cohort Background: The variety and limitations of current laboratory methods for estimating HIV-incidence has driven attempts to improve and standardize the performance of serological ‘Tests for Recent HIV-Infections’ (TRI). ...
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2006-11-01ZeitschriftenartikelImprovement of a national public health surveillance system through use of a quality circle Surveillance systems for infectious diseases build the basis for effective public health measures in the prevention and control of infectious diseases. Assessing and improving the quality of such national surveillance ...
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2011-05-31ZeitschriftenartikelImprovement of H5N1 influenza vaccine viruses: Influence of internal gene segments of avian and human origin on production and hemagglutinin content The H5N1-clade 1 influenza vaccine strain NIBRG-14 produces exceptionally low amounts of antigen, a problem recently encountered also for initial pandemic H1N1-2009 vaccine seeds. Here, we report on a strategy that may ...
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2016-12-02ZeitschriftenartikelImproving Ebola infection prevention and control in primary healthcare facilities in Sierra Leone: a single-group pretest post-test, mixed-methods study Background: Accomplishing infection prevention and control (IPC) in health facilities in Sub-Saharan Africa is challenging. Owing to poor IPC, healthcare workers (HCWs) were frequently infected during Sierra Leone's Ebola ...
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2016-10-13ZeitschriftenartikelImproving influenza virological surveillance in Europe: strain-based reporting of antigenic and genetic characterisation data, 11 European countries, influenza season 2013/14 Influenza antigenic and genetic characterisation data are crucial for influenza vaccine composition decision making. Previously, aggregate data were reported to the European Centre for Disease Prevention and Control by ...
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2020-12-23ZeitschriftenartikelImproving National Intelligence for Public Health Preparedness: a methodological approach to finding local multi-sector indicators for health security The COVID-19 epidemic is the latest evidence of critical gaps in our collective ability to monitor country-level preparedness for health emergencies. The global frameworks that exist to strengthen core public health ...
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2019-07-11ZeitschriftenartikelImproving preparedness to respond to cross-border hepatitis A outbreaks in the European Union/European Economic Area: towards comparable sequencing of hepatitis A virus Introduction Sequence-based typing of hepatitis A virus (HAV) is important for outbreak detection, investigation and surveillance. In 2013, sequencing was central to resolving a large European Union (EU)-wide outbreak ...
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2018-03-15ZeitschriftenartikelImproving the inclusion and participation of children and adolescents with a migration background in KiGGS Wave 2 In the context of health monitoring at the Robert Koch Institute, the baseline study of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS) surveyed a sample of children and adolescents ...
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2019-03-14ZeitschriftenartikelImproving the information base regarding the health of people with a migration background. Project description and initial findings from IMIRA Germany is an immigration country and nearly a quarter of its population has a migration background. Thus, there is increasingly a need for reliable information on the health situation of people with a migration background. ...
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2020-01-14ZeitschriftenartikelImproving tuberculosis surveillance by detecting international transmission using publicly available whole genome sequencing data Improving the surveillance of tuberculosis (TB) is one of the eight core activities identified by the World Health Organization (WHO) and the European Respiratory Society to achieve TB elimination, defined as less than one ...
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2013-06-04ZeitschriftenartikelIn der Diskussion: Können die Alzheimer- und Parkinson-Krankheit durch selbstreplizierende Proteinpartikel übertragen werden? Die Alzheimer-Krankheit und die Parkinson-Krankheit gehen - wie Prionerkrankungen - mit einer Fehlfaltung und Aggregation körpereigener Proteine im zentralen Nervensystem einher, der mutmaßlich als gemeinsames molekulares ...
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2008-04-30ZeitschriftenartikelIn Deutschland selten auftretende Infektionskrankheiten – Ergebnisse aus der Meldepflicht. Ergebnisse aus der MeldepflichtSelten auftretende Infektionskrankheiten haben in Deutschland eine große Bedeutung: Einige von ihnen erfordern bei ihrem Auftreten besondere Maßnahmen und Vorkehrungen, um eine Weiterverbreitung zu verhindern (z. B. ...
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2015-06-19ZeitschriftenartikelIn Silico Prediction and Experimental Confirmation of HA Residues Conferring Enhanced Human Receptor Specificity of H5N1 Influenza A Viruses Newly emerging influenza A viruses (IAV) pose a major threat to human health by causing seasonal epidemics and/or pandemics, the latter often facilitated by the lack of pre-existing immunity in the general population. Early ...
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2015-11-03ZeitschriftenartikelIn vitro activity of ceftobiprole against key pathogens associated with pneumonia in hospitalized patients: results from the PEG surveillance study, 2010 Empirical treatment of hospital-acquired pneumonia (HAP) has increasingly been threatened by methicillin-resistant Staphylococcus aureus (MRSA) and multidrug resistant Gram-negative pathogens. In contrast, empirical treatment ...
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2019-01-21ZeitschriftenartikelIn vitro comparison of currently available and investigational antiviral agents against pathogenic human double-stranded DNA viruses: A systematic literature review Background Double-stranded (ds) DNA virus infections often occur concomitantly in immunocompromised patients. We performed a systematic search of published in vitro activity for nine approved and investigational antivirals ...
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2013-04-29ZeitschriftenartikelIn vitro efficacy of cold atmospheric pressure plasma on S. sanguinis biofilms in comparison of two test models In vitro Wirksamkeit von kaltem Atmosphärendruckplasma gegen S. sanguinis Biofilme im Vergleich zweier PrüfmodelleDental plaque critically affects the etiology of caries, periodontitis and periimplantitis. The mechanical removal of plaque can only be performed partially due to limited accessibility. Therefore, plaque still represents ...
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2022-03-04ZeitschriftenartikelIn vitro maturation of Toxoplasma gondii bradyzoites in human myotubes and their metabolomic characterization The apicomplexan parasite Toxoplasma gondii forms bradyzoite-containing tissue cysts that cause chronic and drug-tolerant infections. However, current in vitro models do not allow long-term culture of these cysts to maturity. ...
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2016-05-24ZeitschriftenartikelIn vivo evidence for ribavirin-induced mutagenesis of the hepatitis E virus genome Objective: Hepatitis E virus (HEV) infection can take chronic courses in immunocompromised patients potentially leading to liver cirrhosis and liver failure. Ribavirin (RBV) is currently the only treatment option for many ...
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2022-06-09ZeitschriftenartikelIn(tra)-Action Review (IAR): COVID-19-Management an IGV-benannten Flughäfen in Deutschland, September 2020 bis Mai 2021 Die Maßnahmen zur Eindämmung der COVID-19-Pandemie haben auch den Luftfahrtsektor stark beeinflusst und die zuständigen Gesundheitsbehörden vor neue Herausforderungen gestellt. Unter Federführung des RKI wurde am 20.05.2021 ...