Browsing Artikel in Fachzeitschriften by Title
Now showing items 3688-3707 of 5140
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2022-03-31ZeitschriftenartikelRadiation exposure by medical X-ray applications Background: Radioactive material and ionising radiation play a central role in medical diagnostics and therapy. The benefit of ionising radiation is opposed by the risk of irreparable damage of the human organism. This ...
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2015-09-17ZeitschriftenartikelRAMBO-K: Rapid and Sensitive Removal of Background Sequences from Next Generation Sequencing Data Background: The assembly of viral or endosymbiont genomes from Next Generation Sequencing (NGS) data is often hampered by the predominant abundance of reads originating from the host organism. These reads increase the ...
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2015-11-24ZeitschriftenartikelRandom sampling of the Central European bat fauna reveals the existence of numerous hitherto unknown adenoviruses From over 1250 extant species of the order Chiroptera, 25 and 28 are known to occur in Germany and Hungary, respectively. Close to 350 samples originating from 28 bat species (17 from Germany, 27 from Hungary) were screened ...
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2012-06-29ZeitschriftenartikelRapid and high-throughput detection of highly pathogenic bacteria by Ibis PLEX-ID technology In this manuscript, we describe the identification of highly pathogenic bacteria using an assay coupling biothreat group-specific PCR with electrospray ionization mass spectrometry (PCR/ESI-MS) run on an Ibis PLEX-ID ...
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2011-01-14ZeitschriftenartikelRapid and Highly Efficient Method for Scarless Mutagenesis within the Salmonella enterica Chromosome Direct manipulation of bacterial chromosomes by recombination-based techniques has become increasingly important for both cognitive and applied research. Here we demonstrate, for the first time, the combination of the Red ...
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2013-04-17ZeitschriftenartikelRapid and reliable detection of bacterial endospores in environmental samples by diagnostic electron microscopy combined with X-ray microanalysis Diagnostic negative staining electron microscopy is a front-line method for the rapid investigation of environmental and clinical samples in emergency situations caused by bioterrorism or outbreaks of an infectious disease. ...
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2021-07-30ZeitschriftenartikelRapid and Robust Continuous Purification of High-Titer Hepatitis B Virus for In Vitro and In Vivo Applications Available treatments for hepatitis B can control the virus but are rarely curative. This led to a global initiative to design new curative therapies for the 257 million patients affected. Discovery and development of these ...
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2016-12-09ZeitschriftenartikelRapid and sensitive point-of-care detection of Orthopoxviruses by ABICAP immunofiltration Background: The rapid and reliable detection of infectious agents is one of the most challenging tasks in scenarios lacking well-equipped laboratory infrastructure, like diagnostics in rural areas of developing countries. ...
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2014-09-05ZeitschriftenartikelRapid and simultaneous detection of ricin, staphylococcal enterotoxin B and saxitoxin by chemiluminescence-based microarray immunoassay Simultaneous detection of small and large molecules on microarray immunoassays is a challenge that limits some applications in multiplex analysis. This is the case for biosecurity, where fast, cheap and reliable simultaneous ...
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2011-03-25ZeitschriftenartikelRapid detection of anti-Vaccinia virus neutralizing antibodies Increasing infections with Monkeypox and Cowpox viruses pose a continuous and growing threat to human health. The standard method for detecting poxvirus neutralizing antibodies is the plaque-reduction neutralization test ...
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2021-12-27ZeitschriftenartikelRapid Diagnosis of Central Nervous System Scedosporiosis by Specific Quantitative Polymerase Chain Reaction Applied to Formalin-Fixed, Paraffin-Embedded Tissue Scedosporium (S.) apiospermum is a typical mold causing cerebral abscesses, often after near-drowning. Infections are associated with high morbidity and mortality due to diagnostic challenges including the need for prolonged ...
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2012-06-29ZeitschriftenartikelRapid Discrimination of Salmonella enterica Serovar Typhi from Other Serovars by MALDI-TOF Mass Spectrometry Systemic infections caused by Salmonella enterica are an ongoing public health problem especially in Sub-Saharan Africa. Essentially typhoid fever is associated with high mortality particularly because of the increasing ...
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2021-10-14ZeitschriftenartikelRapid incidence estimation from SARS-CoV-2 genomes reveals decreased case detection in Europe during summer 2020 By October 2021, 230 million SARS-CoV-2 diagnoses have been reported. Yet, a considerable proportion of cases remains undetected. Here, we propose GInPipe, a method that rapidly reconstructs SARS-CoV-2 incidence profiles ...
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2014-03-06ZeitschriftenartikelRapid Molecular Assays for the Detection of Yellow Fever Virus in Low-Resource Settings Background: Yellow fever (YF) is an acute viral hemorrhagic disease transmitted by Aedes mosquitoes. The causative agent, the yellow fever virus (YFV), is found in tropical and subtropical areas of South America and ...
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2016-01-01ZeitschriftenartikelRapid outbreak sequencing of Ebola virus in Sierra Leone identifies transmission chains linked to sporadic cases To end the largest known outbreak of Ebola virus disease (EVD) in West Africa and to prevent new transmissions, rapid epidemiological tracing of cases and contacts was required. The ability to quickly identify unknown ...
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2017-03-05ZeitschriftenartikelRapid radiation of treponema pallidum pertenue in wild non-human primates
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2018-03-22ZeitschriftenartikelRapid Viral Diagnosis of Orthopoxviruses by Electron Microscopy: Optional or a Must? Diagnostic electron microscopy (DEM) was an essential component of viral diagnosis until the development of highly sensitive nucleic acid amplification techniques (NAT). The simple negative staining technique of DEM was ...
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2011-01-19ZeitschriftenartikelrapidSTRIPE H1N1 Test for Detection of the Pandemic Swine Origin Influenza A (H1N1) Virus The rapidSTRIPE H1N1 test, based on a nucleic acid lateral-flow assay, has been developed for diagnosis of a swine-origin influenza A (H1N1) virus. This test is simple and cost-effective and allows specific detection of ...
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2011-08-04Zeitschriftenartikelrapmad: Robust analysis of peptide microarray data Background: Peptide microarrays offer an enormous potential as a screening tool for peptidomics experiments and have recently seen an increased field of application ranging from immunological studies to systems biology. ...
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2023-12-13ZeitschriftenartikelRare diseases in Germany - Developments in the status of medical care Background: Rare diseases are a heterogeneous group of complex clinical patterns, which more often than not run a chronic course. The fact that they are rare complicates the provision of medical care for the specific ...