Artikel in Fachzeitschriften: Neuzugänge
Anzeige der Publikationen 4421-4440 von 6067
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2015-03-12ZeitschriftenartikelImpact of 10- and 13-valent pneumococcal conjugate vaccines on incidence of invasive pneumococcal disease in children aged under 16 years in Germany, 2009 to 2012 We assessed the impact of 10-valent and 13-valent pneumococcal vaccines (PCV10 and PCV13), which were introduced in Germany in 2009, on the incidence of meningitis and non-meningitis invasive pneumococcal disease (IPD) in ...
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2015-03-17ZeitschriftenartikelFrom pills to patients: an evaluation of data sources to determine the number of people living with HIV who are receiving antiretroviral therapy in Germany Background: This study aimed to determine the number of people living with HIV receiving antiretroviral therapy (ART) between 2006 and 2013 in Germany by using the available numbers of antiretroviral drug prescriptions ...
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2015-03-20ZeitschriftenartikelAntiretroviral Therapy and Reasons for Not Taking It among Men Having Sex with Men (MSM)—Results from the European MSM Internet Survey (EMIS) Background: The preventive effects of antiretroviral treatment (ART) on onward transmission of HIV are a major reason for broadening eligibility for ART. In the WHO European Region, surveillance reveals substantial ...
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2015-02-12ZeitschriftenartikelHIV-1 IN/Pol recruits LEDGF/p75 into viral particles Background: The dynamic interaction between HIV and its host governs the replication of the virus and the study of the virus-host interplay is key to understand the viral lifecycle. The host factor lens epithelium-derived ...
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2015-03-08ZeitschriftenartikelPrevalence and correlates of frailty among older adults: findings from the German health interview and examination survey Background: Despite having the third highest proportion of people aged 60 years and older in the world, Germany has been recently reported as having the lowest prevalence of frailty of 15 European countries. The objective ...
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2015-02-27ZeitschriftenartikelCross-border comparison of the Dutch and German guidelines on multidrug-resistant Gram-negative microorganisms Background: In all European countries, hospital-acquired infections caused by Gram-negative multidrug-resistant microorganisms (GN-MDRO) are a major health threat, as these pathogens cannot be adequately treated anymore, ...
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2015-02-22ZeitschriftenartikelOutbreak of cryptosporidium hominis following river flooding in the city of Halle (Saale), Germany, August 2013 Background: During weeks 32–33, 2013, 24 cases of cryptosporidiosis were notified in the city of Halle (annual mean 2008–2012: 9 cases). We investigated the outbreak to identify the source and recommend control measures, ...
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2015-02-26ZeitschriftenartikelIPred - integrating ab initio and evidence based gene predictions to improve prediction accuracy Background: Gene prediction is a challenging but crucial part in most genome analysis pipelines. Various methods have evolved that predict genes ab initio on reference sequences or evidence based with the help of ...
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2015-02-04ZeitschriftenartikelMouse conventional dendritic cells can be universally classified based on the mutually exclusive expression of XCR1 and SIRPα Since the identification of mouse dendritic cells (DC) in the early 70s, all attempts to consistently classify the identified functional DC subpopulations according to their surface molecule expression failed. In the absence ...
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2015-02-16ZeitschriftenartikelRelation between Overweight/Obesity and Self-Rated Health Among Adolescents in Germany. Do Socio-Economic Status and Type of School Have an Impact on That Relation? This study investigates the relation between overweight/obesity and self-rated health (SRH), and whether this relation varies by social factors. Data was taken from the German Health Interview and Examination Survey for ...
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2015-02-06ZeitschriftenartikelVisceral leishmaniasis diagnosis and reporting delays as an obstacle to timely response actions in Nepal and India Background: To eliminate visceral leishmaniasis (VL) in India and Nepal, challenges of VL diagnosis, treatment and reporting need to be identified. Recent data indicate that VL is underreported and patients face delays ...
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2015-02-10ZeitschriftenartikelEvaluation of Virus Inactivation by Formaldehyde to Enhance Biosafety of Diagnostic Electron Microscopy Formaldehyde (FA) fixation of infectious samples is a well-established protocol in diagnostic electron microscopy of viruses. However, published experimental data that demonstrate virus inactivation by these fixation ...
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2015-02-02ZeitschriftenartikelMetagenomic Profiling of Known and Unknown Microbes with MicrobeGPS Microbial community profiling identifies and quantifies organisms in metagenomic sequencing data using either reference based or unsupervised approaches. However, current reference based profiling methods only report the ...
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2015-02-06ZeitschriftenartikelIsolation and Functional Characterization of the Novel Clostridium botulinum Neurotoxin A8 Subtype Botulism is a severe neurological disease caused by the complex family of botulinum neurotoxins (BoNT). Based on the different serotypes known today, a classification of serotype variants termed subtypes has been proposed ...
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2014-12-22ZeitschriftenartikelMode differences in a mixed-mode health interview survey among adults Background: Health interview surveys are important data sources for empirical research in public health. However, the diversity of methods applied, such as in the mode of data collection, make it difficult to compare ...
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2014-12-18ZeitschriftenartikelFoodborne hepatitis A outbreak associated with bakery products in northern Germany, 2012 In October 2012, a hepatitis A (HA) outbreak with 83 laboratory-confirmed cases occurred in Lower Saxony. We defined primary outbreak cases as people with laboratory-confirmed HA and symptom onset between 8 October and 12 ...
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2015-01-23ZeitschriftenartikelSoluble MICB protein levels and platelet counts during hepatitis B virus infection and response to hepatocellular carcinoma treatment Background: The human major histocompatibility complex class I polypeptide-related sequence B (MICB) is a protein that modulates the NK and T cell activation through the NKG2D receptor and is related to several diseases ...
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2015-01-28ZeitschriftenartikelForschung an humanen embryonalen Stammzellen in Deutschland Historischer Rückblick und gegenwärtiger StandDie Katholische Kirche gehört zu den schärfsten Kritikern der Biowissenschaften. Sie erkennt die positiven Fortschritte an, bemängelt aber Grenzüberschreitungen, die aus ihrer Sicht dem Menschen letztlich nicht dienen. Vor ...
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2014-12-19ZeitschriftenartikelDiscrete and overlapping functions of peptidoglycan synthases in growth, cell division and virulence of Listeria monocytogenes Upon ingestion of contaminated food, Listeria monocytogenes can cause serious infections in humans that are normally treated with β-lactam antibiotics. These target Listeria's five high molecular weight penicillin-binding ...
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2014-10-11ZeitschriftenartikelFeasibility and acceptance of cervicovaginal self-sampling within the German National Cohort (Pretest 2) Hintergrund und Ziele: In der Nationalen Kohorte (NAKO) werden 100.000 erwachsene Frauen in Deutschland umfassend befragt und untersucht werden. Während Frauengesundheit im Basisinterview thematisiert wird, ist der ...