Artikel in Fachzeitschriften: Recent submissions
Now showing items 1-20 of 6067
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2019-03-07ZeitschriftenartikelHEVnet: a One Health, collaborative, interdisciplinary network and sequence data repository for enhanced network and sequence data repository for enhanced hepatitis E virus molecular typing, characterisation and epidemiological investigations Hepatitis E virus (HEV) is a common cause of acute hepatitis worldwide. In Europe, HEV is a zoonosis transmitted via contaminated pork meat or other pork food products. Genotype 3 is the most prevalent HEV type in the ...
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2019-10-30ZeitschriftenartikelHuman activities link fruit bat presence to Ebola virus disease outbreaks 1. A significant link between forest loss and fragmentation and outbreaks of Ebola virus disease (EVD) in humans has been documented. Deforestation may alter the natural circulation of viruses and change the composition, ...
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2019-11-14ZeitschriftenartikelDecreasing and stabilising trends of antimicrobial consumption and resistance in Eschirichia coli and Klebsiella pneumniae in segmented regression analysis, European Union/European Economic Area, 2001 to 2018 Investments to reduce the spread of antimicrobial resistance (AMR) in the European Union have been made, including efforts to strengthen prudent antimicrobial use. Using segmented regression, we report decreasing and ...
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2019-03-18ZeitschriftenartikelAssessment of the use and need for an integrated molecular surveillance of tuberculosis: an online survey in Germany Background The implementation of an integrated molecular surveillance (IMS) of tuberculosis (TB) is of high priority for TB control. IMS is defined as the systematic inclusion of molecular typing results in the national ...
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2019-12-06ZeitschriftenartikelAssessment of a data quality guideline by representatives of German epidemiologic cohort studies High data quality is a precondition for valid scientific conclusions. Indicators should therefore routinely be used to evaluate data quality within the life cycle of health studies. In this project, 15 representatives of ...
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2019-11-13ZeitschriftenartikelIdentification of cross-reactive antibodies for the detection of lymphocytes, myeloid cells an haematopoietic precursors in the naked mole rat The naked mole rat (Heterocephalus glaber, NMR) is a rodent with exceptional longevity, low rates of age-related diseases and spontaneous carcinogenesis. The NMR represents an attractive animal model in longevity and cancer ...
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2019-12-18ZeitschriftenartikelA Bayesian Monte Carlo approach for predicting the spread of infectious diseases In this paper, a simple yet interpretable, probabilistic model is proposed for the prediction of reported case counts of infectious diseases. A spatio-temporal kernel is derived from training data to capture the typical ...
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2026-08-27ZeitschriftenartikelPrEP in Deutschland – Befragung der Deutschen Arbeitsgemeinschaft ambulant tätiger Ärztinnen und Ärzte für Infektionskrankheiten und HIV-Medizin (dagnä e. V.) in HIV-Schwerpunkteinrichtungen Eine Infektion mit dem humanen Immundefizienzvirus (HIV) kann durch eine Präexpositionsprophylaxe (PrEP) verhindert werden. Die retrospektive Befragung von 29 HIV-Schwerpunktzentren des dagnä-Netzwerks in zehn Bundesländern ...
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2019ZeitschriftenartikelThe Diagnosis and Treatment of Tuberculosis Background: Around 10 million people worldwide contract tuberculosis every year. According to the World Health Organization (WHO), approximately one-quarter of the world’s population is latently infected with Mycobacterium ...
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2019-01-02ZeitschriftenartikelAre European HIV cohort data within EoroCoord representative of the diagnosed HIV population? Objective: HIV cohorts are an important source of clinical data for informing public health policies and programmes. However, the generalizability of cohort findings to the wider population of people diagnosed with HIV ...
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2019-06-20ZeitschriftenartikelSystems-level Analysis Reveals Multiple Modulators of Epithelial-mesenchymal Transition and Identifies DNAJB4 and CD81 as Novel Metastatis Inducers in Breast Cancer Epithelial-mesenchymal transition (EMT) is driven by complex signaling events that induce dramatic biochemical and morphological changes whereby epithelial cells are converted into cancer cells. However, the underlying ...
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2019-04-30ZeitschriftenartikelExtended-Spectrum Beta-Lactamase (ESBL)-Producing Escherichia coli Isolated from Flies in the Urban Center of Berlin, Germany Background: The monitoring of antimicrobial resistance (AMR) in microorganisms that circulate in the environment is an important topic of scientific research and contributes to the development of action plans to combat the ...
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2019-12-30ZeitschriftenartikelRORγt+ Treg to Th17 ratios correlate with susceptibility to Giardia infection Infections with Giardia are among the most common causes of food and water-borne diarrheal disease worldwide. Here, we investigated Th17, Treg and IgA responses, and alterations in gut microbiota in two mouse lines with ...
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2018-04-11ZeitschriftenartikelOver-The-Counter (OTC) Drug Consumption among Adults Living in Germany: Results from the German Health Interview and Examination Survey for Adults 2008-2011 (DEGS1) In order to assess the effects of prescription-only (Rx) to over-the-counter (OTC) drug switches and related policies, it is imperative to distinguish self-medication from OTC drug use. The objective of this study was to ...
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2018-10-30ZeitschriftenartikelMetabolic interactions between Toxoplasma gondii an its host Toxoplasma gondii is an obligate intracellular parasite belonging to the phylum Apicomplexa that infects all warm-blooded animals, including humans. T. gondii can replicate in every nucleated host cell by orchestrating ...
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2018-11-01ZeitschriftenartikelUpsurge in echovirus 30 detections in five EU/EEA countries, April to September, 2018 An upsurge in Echovirus 30 (E30) infections, associated with meningitis/meningoencephalitis, has been observed in Denmark, Germany, the Netherlands, Norway and Sweden in the period April to September 2018, compared with ...
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2018-02ZeitschriftenartikelPrevalence and Clinical Correlates of Chronic Hepatitis E Infection in German Renal Transplant RecipientsWith Elevated Liver Enzymes Background Elevated liver enzymes are frequently observed in renal transplant recipients and warrant further exploration. In immunosuppressed patients, hepatitis E virus (HEV) infection may cause chronic hepatitis, ...
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2018-12ZeitschriftenartikelSurvey of Ebola Viruses in Frugivorous and Insectivorous Bats in Guinea, Cameroon, and the Democratic Rpublic of the Congo, 2015-2017 To clarify the role of bats in the ecology of Ebola viruses, we assessed the prevalence of Ebola virus antibodies in a large-scale sample of bats collected during 2015–2017 from countries in Africa that have had previous ...
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2018-05ZeitschriftenartikelDimerization of the cellular prion protein inhibits propagation of scrapie prions A central step in the pathogenesis of prion diseases is the conformational transition of the cellular prion protein (PrPC) into the scrapie isoform, denoted PrPSc. Studies in transgenic mice have indicated that this ...
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2018-08-01ZeitschriftenartikelCorrigendum: SeroBA: rapid high-throughput serotyping of Streptococcus pneumoniae from whole genome sequence data Streptococcus pneumoniae is responsible for 240 000–460 000 deaths in children under 5 years of age each year. Accurate identification of pneumococcal serotypes is important for tracking the distribution and evolution of ...