Browsing Artikel in Fachzeitschriften by Author "Leendertz, Fabian H."
Now showing items 1-20 of 44
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2017-09-29ZeitschriftenartikelA Cross-Sectional Serosurvey of Anti-Orthopoxvirus Antibodies in Central and Western Africa Leendertz, Siv Aina J.; Stern, Daniel; Theophil, Dennis; Anoh, Etile; Mossoun, Arsène; Schubert, Grit; Wiersma, Lidewij; Akoua-Koffi, Chantal; Couacy-Hymann, Emmanuel; Muyembe-Tamfum, Jean-Jacques; Karhemere, Stomy; Pauly, Maude; Schrick, Livia; Leendertz, Fabian H.; Nitsche, AndreasSince the eradication of smallpox and the subsequent discontinuation of the worldwide smallpox vaccination program, other Orthopoxviruses beside Variola virus have been increasingly representing a risk to human health. To ...
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2017-09-18ZeitschriftenartikelA novel Coltivirus-related virus isolated from free-tailed bats from Côte d’Ivoire is able to infect human cells in vitro Weiss, Sabrina; Dabrowski, Piotr Wojtek; Kurth, Andreas; Leendertz, Siv Aina J.; Leendertz, Fabian H.Background: Zoonotic transmission events play a major role in the emergence of novel diseases. While such events are virtually impossible to predict, wildlife screening for potential emerging pathogens can be a first ...
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2019-03-19ZeitschriftenartikelA Novel Orthohepadnavirus Identified in a Dead Maxwell’s Duiker (Philantomba maxwellii) in Taï National Park, Côte d’Ivoire Gogarten, Jan F.; Ulrich, Markus; Bhuva, Nishit; Garcia, Joel; Jain, Komal; Lee, Bohyun; Löhrich, Therese; Oleynik, Alexandra; Couacy-Hymann, Emmanuel; Fuh Neba, Terence; Mishra, Nischay; Briese, Thomas; Calvignac-Spencer, Sébastien; Lipkin, W. Ian; Leendertz, Fabian H.New technologies enable viral discovery in a diversity of hosts, providing insights into viral evolution. We used one such approach, the virome capture sequencing for vertebrate viruses (VirCapSeq-VERT) platform, on 21 ...
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2015-05-20ZeitschriftenartikelAdenovirus in Rural Côte D`Ivoire: High Diversity and Cross-Species Detection Pauly, Maude; Akoua-Koffi, Chantal; Buchwald, Nanina; Schubert, Grit; Weiss, Sabrina; Couacy-Hymann, Emmanuel; Anoh, Augustin Etile; Mossoun, Arsène; Calvignac-Spencer, Sébastien; Leendertz, Siv Aina; Leendertz, Fabian H.; Ehlers, BernhardThe Taï region in Western Côte d`Ivoire is characterized by extensive overlap of human and animal habitats. This could influence patterns of adenovirus transmission between humans and domestic animals. Fecal samples from ...
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2017-03-28ZeitschriftenartikelAncient Recombination Events between Human Herpes Simplex Viruses Burrel, Sonia; Boutolleau, David; Ryu, Diane; Agut, Henri; Merkel, Kevin; Leendertz, Fabian H.; Calvignac-Spencer, SébastienHerpes simplex viruses 1 and 2 (HSV-1 and HSV-2) are seen as close relatives but also unambiguously considered as evolutionary independent units. Here, we sequenced the genomes of 18 HSV-2 isolates characterized by divergent ...
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2016-11-30ZeitschriftenartikelAssessing the feasibility of fly based surveillance of wildlife infectious diseases Hoffmann, Constanze; Stockhausen, Melanie; Merkel, Kevin; Calvignac-Spencer, Sébastien; Leendertz, Fabian H.Monitoring wildlife infectious agents requires acquiring samples suitable for analyses, which is often logistically demanding. A possible alternative to invasive or non-invasive sampling of wild-living vertebrates is the ...
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2016-09-08ZeitschriftenartikelBacillus cereus Biovar Anthracis Causing Anthrax in Sub-Saharan Africa—Chromosomal Monophyly and Broad Geographic Distribution Antonation, Kym S.; Grützmacher, Kim; Dupke, Susann; Mabon, Philip; Zimmermann, Fee; Lankester, Felix; Peller, Tianna; Feistner, Anna; Todd, Angelique; Herbinger, Ilka; Nys, Hélène de; Muyembe-Tamfun, Jean-Jacques; Karhemere, Stomy; Wittig, Roman M.; Couacy-Hymann, Emmanuel; Grunow, Roland; Calvignac-Spencer, Sébastien; Corbett, Cindi R.; Klee, Silke; Leendertz, Fabian H.Through full genome analyses of four atypical Bacillus cereus isolates, designated B. cereus biovar anthracis, we describe a distinct clade within the B. cereus group that presents with anthrax-like disease, carrying ...
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2021-02-17ZeitschriftenartikelChallenges in interpreting SARS-CoV-2 serological results in African countries Ndaye, Antoine Nkuba; Hoxha, Ana; Madinga, Joule; Marien, Joachim; Peeters, Martine; Leendertz, Fabian H.; Mundeke, Steve Ahuka; Arien, Kevin K.; Tanfumu, Jean-Jaques Muyembe; Kingebeni, Placide Mbala; Vanlerberghe, VeerleA diagnosis of COVID-19 is based on a positive PCR test for SARS-CoV-2. Over the past year, PCR testing capacity has varied globally due to the availability of tests, and testing strategies have targeted mainly symptomatic ...
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2018-02-09ZeitschriftenartikelClinically Relevant ESBL-Producing K. pneumoniae ST307 and E. coli ST38 in an Urban West African Rat Population Schaufler, Katharina; Nowak, Kathrin; Düx, Ariane; Semmler, Torsten; Villa, Laura; Kourouma, Laye; Bangoura, Karim; Wieler, Lothar H.; Leendertz, Fabian H.; Guenther, SebastianHigh-risk ESBL-producing Enterobacteriaceae (ESBL-E) have been described in wild birds and rodents worldwide. Rats are of special interest not only due to their indicator role for environmental pollution with multi-resistant ...
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2019-08-01ZeitschriftenartikelCytomegalovirus distribution and evolution in hominines Murthy, Sripriya; O’Brien, Kathryn; Agbor, Anthony; Angedakin, Samuel; Arandjelovic, Mimi; Ayuk Ayimisin, Emmanuel; Bailey, Emma; Bergl, Richard A.; Brazzola, Gregory; Dieguez, Paula; Eno-Nku, Manasseh; Eshuis, Henk; Fruth, Barbara; Gillespie, Thomas R.; Ginath, Yisa; Maryke, Gray; Herbinger, Ilka; Jones, Sorrel; Kehoe, Laura; Kühl, Hjalmar; Kujirakwinja, Deo; Lee, Kevin; Madinda, Nadège F.; Mitamba, Guillain; Muhindo, Emmanuel; Nishuli, Radar; Ormsby, Lucy J.; Petrzelkova, Klara J.; Plumptre, Andrew J.; Robbins, Martha M.; Sommer, Volker; Ter Heegde, Martijn; Todd, Angelique; Tokunda, Raymond; Wessling, Erin; Jarvis, Michael V.; Leendertz, Fabian H.; Ehlers, Bernhard; Calvignac-Spencer, SébastienHerpesviruses are thought to have evolved in very close association with their hosts. This is notably the case for cytomegaloviruses (CMVs; genus Cytomegalovirus) infecting primates, which exhibit a strong signal of ...
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2017-12-29ZeitschriftenartikelCytomegaloviruses in a Community of Wild Nonhuman Primates in Taï National Park, Côte D’Ivoire Anoh, Augustin Etile; Murthy, Sripriya; Akoua-Koffi, Chantal; Couacy-Hymann, Emmanuel; Leendertz, Fabian H.; Calvignac-Spencer, Sébastien; Ehlers, BernhardCytomegaloviruses (CMVs) are known to infect many mammals, including a number of nonhuman primates (NHPs). However, most data available arose from studies led on captive individuals and little is known about CMV diversity ...
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2019-12-03ZeitschriftenartikelDifferences in MHC-B diversity and KIR epitopes in two populations of wild chimpanzees Maibach, Vincent; Langergraber, Kevin; Leendertz, Fabian H.; Wittig, Roman M.; Vigilant, LindaThe major histocompatibility complex (MHC) class I genes play a critical role within the immune system, both by the presentation of antigens from intracellular pathogens to immunocompetent cells and by the interaction with ...
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2021-03-15ZeitschriftenartikelDiscovery of Novel Herpes Simplexviruses in Wild Gorillas, Bonobos, and Chimpanzees Supports Zoonotic Origin of HSV-2 Wertheim, Joel O.; Hostager, Reilly; Ryu, Diane; Merkel, Kevin; Angedakin, Samuel; Arandjelovic, Mimi; Ayimisin, Emmanuel Ayuk; Babweteera, Fred; Bessone, Mattia; Brun-Jeffrey, Kathryn J.; Dieguez, Paula; Eckardt, Winnie; Fruth, Barbara; Herbinger, Ilka; Jones, Sorrel; Kuehl, Hjalmar; Langergraber, Kevin E.; Lee, Kevin; Madinda, Nadege F.; Metzger, Sonja; Ormsby, Lucy Jayne; Robbins, Martha M.; Sommer, Volker; Stoinski, Tara; Wessling, Erin G.; Wittig, Roman M.; Yuh, Yisa Ginath; Leendertz, Fabian H.; Calvignac-Spencer, SébastienViruses closely related to human pathogens can reveal the origins of human infectious diseases. Human herpes simplexvirus type 1 (HSV-1) and type 2 (HSV-2) are hypothesized to have arisen via host-virus codivergence and ...
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2019-05-16ZeitschriftenartikelElevated neopterin levels in wild, healthy chimpanzees indicate constant investment in unspecific immune system Behringer, Verena; Stevens, Jeroen M. G.; Wittig, Roman M.; Crockford, Catherine; Zuberbühler, Klaus; Leendertz, Fabian H.; Deschner, TobiasBackground Ecological immunology proposes that the optimal immune defence, and the costs coming with it, vary across environments. In environments with higher pathogen load, the immune system should experience greater ...
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2021-10-01ZeitschriftenartikelEmergence and spread of SARS-CoV-2 lineage B.1.620 with variant of concern-like mutations and deletions Dudas, Gytis; Hong, Samuel L.; Potter, Barney I.; Calvignac-Spencer, Sébastien; Niatou-Singa, Frédéric S.; Tombolomako, Thais B.; Fuh-Neba, Terence; Vickos, Ulrich; Ulrich, Markus; Leendertz, Fabian H.; Khan, Kamran; Huber, Carmen; Watts, Alexander; Olendraitė, Ingrida; Snijder, Joost; Wijnant, Kim N.; Bonvin, Alexandre M.J.J.; Martres, Pascale; Behillil, Sylvie; Ayouba, Ahidjo; Foudi-Maïdadi, Martin; Meta-Djomsi, Dowbiss; Gowde, Celestin; Butel, Christelle; Šimaitis, Aistis; Gabrielaitė, Miglė; Katėnaitė, Monika; Norvilas, Rimvydas; Raugaitė, Ligita; Koyaweda, Giscard Wilfried; Kandou, Jephté Kaleb; Jonikas, Rimvydas; Nasvytienė, Inga; Žemeckienė, Živilė; Gečys, Dovydas; Tamušauskaitė, Kamilė; Norkienė, Milda; Vasiliūnaitė, Emilija; Žiogienė, Danguolė; Timinskas, Albertas; Šukys, Marius; Šarauskas, Mantas; Alzbutas, Gediminas; Amuri Aziza, Adrienne; Lusamaki, Eddy Kinganda; Makangara Cigolo, Jean-Claude; Muyembe Mawete, Francisca; Lofiko, Emmanuel Lokilo; Mbala-Kingebeni, Placide; Muyembe-Tamfum, Jean-Jacques; Belizaire, Marie Roseline Darnycka; Essomba, René Ghislain; Okomo Assoumou, Marie Claire; Mboringong, Akenji Blaise; Dieng, Alle Baba; Jouzapaitė, Dovilė; Hosch, Salome; Obama, Justino; Ondo'o Ayekaba, Mitoha; Naumovas, Daniel; Pautienius, Arnoldas; Rafaï, Clotaire Donatien; Vitkauskienė, Astra; Ugenskienė, Rasa; Gedvilaitė, Alma; Čereškevičius, Darius; Lesauskaitė, Vaiva; Žemaitis, Lukas; Griškevičius, Laimonas; Baele, GuyDistinct SARS-CoV-2 lineages, discovered through various genomic surveillance initiatives, have emerged during the pandemic following unprecedented reductions in worldwide human mobility. We here describe a SARS-CoV-2 ...
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2022-01-25ZeitschriftenartikelEvidence against Zika virus infection of pets and peri-domestic animals in Latin America and Africa Oliveira-Filho, Edmilson F. de; Carneiro, Ianei O.; Fischer, Carlo; Kühne, Arne; Postigo-Hidalgo, Ignacio; Ribas, Jorge R. L.; Schumann, Peggy; Nowak, Kathrin; Gogarten, Jan F.; Lamballerie, Xavier de; Dantas-Torres, Filipe; Netto, Eduardo Martins; Franke, Carlos Roberto; Couacy-Hymann, Emmanuel; Leendertz, Fabian H.; Drexler, Jan FelixDecades after its discovery in East Africa, Zika virus (ZIKV) emerged in Brazil in 2013 and infected millions of people during intense urban transmission. Whether vertebrates other than humans are involved in ZIKV transmission ...
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2017-11-06ZeitschriftenartikelEvidence for Human Streptococcus pneumoniae in wild and captive chimpanzees: A potential threat to wild populations Köndgen, Sophie; Calvignac-Spencer, Sebastien; Grützmacher, Kim; Keil, Verena; Mätz-Rensing, Kerstin; Nowak, Kathrin; Metzger, Sonja; Kiyang, John; Lübke-Becker, Antina; Deschner, Tobias; Wittig, Roman M.; Lankester, Felix; Leendertz, Fabian H.Habituation of wild great apes for tourism and research has had a significant positive effect on the conservation of these species. However, risks associated with such activities have been identified, specifically the ...
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2019-10-29ZeitschriftenartikelFly-derived DNA and camera traps are complementary tools for assessing mammalian biodiversity Gogarten, Jan F.; Hoffmann, Constanze; Arandjelovic, Mimi; Sachse, Andreas; Merkel, Kevin; Dieguez, Paula; Agbor, Anthony; Angedakin, Samuel; Brazzola, Gregory; Jones, Sorrel; Langergraber, Kevin E.; Lee, Kevin; Marrocoli, Sergio; Murai, Mizuki; Sommer, Volker; Kühl, Hjalmar; Leendertz, Fabian H.; Calvignac-Spencer, SèbastienBackground Metabarcoding of vertebrate DNA found in invertebrates (iDNA) represents a potentially powerful tool for monitoring biodiversity. Preliminary evidence suggests fly iDNA biodiversity assessments compare favorably ...
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2015-10-05ZeitschriftenartikelGenetic identification of cytomegaloviruses in a rural population of Côte d’Ivoire Anoh, Augustin Etile; Akoua-Koffi, Chantal; Couacy-Hymann, Emmanuel; Pauly, Maude; Schubert, Grit; Mossoun, Arsène; Weiss, Sabrina; Leendertz, Siv Aina J.; Jarvis, Michael A.; Leendertz, Fabian H.; Ehlers, BernhardBackground: Cytomegaloviruses (CMVs) are herpesviruses that infect many mammalian species, including humans. Infection generally passes undetected, but the virus can cause serious disease in individuals with impaired ...
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2015-09-03ZeitschriftenartikelGenome Sequence of a Central Chimpanzee-Associated Polyomavirus Related to BK and JC Polyomaviruses, Pan troglodytes troglodytes Polyomavirus 1 Madinda, Nadège F.; Robbins, Martha M.; Boesch, Christophe; Leendertz, Fabian H.; Ehlers, Bernhard; Calvignac-Spencer, SébastienWe amplified and sequenced the genome of a polyomavirus infecting a central chimpanzee (Pan troglodytes troglodytes). This virus, which is closely related to BK and JC polyomaviruses, may help shed a new light on these ...