2008-11-07Zeitschriftenartikel
Influenza A Virus Inhibits Type I IFN Signaling via NF-κB-Dependent Induction of SOCS-3 Expression
Pauli, Eva-K.; Schmolke, Mirko; Wolff, Thorsten; Viemann, Dorothee; Roth, Johannes; Bode, Johannes G.; Ludwig, Stephan
The type I interferon (IFN) system is a first line of defense against viral infections. Viruses have developed various mechanisms to counteract this response. So far, the interferon antagonistic activity of influenza A ...